Because this was never really a chem intended for humans in any country likely to conduct studies.
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Anabolic Steroids
Dnp...another log thread
- Thread starter Flabbybutt
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Because this was never really a chem intended for humans in any country likely to conduct studies.
Flabbybutt
New Member
At least i had a breakthrough today. That Ec stack is the motherfucking shit!
mindgame1516
Member
im still wondering if the dnp is even real take 1000mg if you dont die then its fake
MrRippedZilla
Member
Carbs don't augment the fat loss effect of dnp, only the heat sides.
It has a lot do with the fact that AMPK activation via DNP can increase insulin sensitivity and insulin sensitivity + carbs = enhanced thermic effect = enhanced heat
I suspect the rate of substrate utilization also plays a role.
Carbs are tend to be digested quicker than protein/fats and, once they're turned into glucose, AMPK forces it to be available for cellular respiration and it gets oxidized. Carbs usually provide the most substrate in the least amount of time so....faster you provide energy substrate = faster you'll produce heat.
Anecdotally, you'll also hear reports of people not feeling the heat when consuming fructose based carbs and I suspect that has a lot do with the fact that's it not as accessible a substrate due to fructose's propensity to reglycogenate in the liver instead of being made available for storage within the muscle cells like starchy carbs.
Except it was a legally available, over the counter drug intended for fat loss in the 30s and does actually have a good amount of data on it
Flabbybutt
New Member
Thanks for checking in. I think that the most compelling information on carbs helping with Dnp weight loss is the calorie deficit that occurs once the carbs are obliterated by the heat reaction. Its convenient, i guess, for those who absolutely need carbs and can balance the carb/calorie intake to arrive at a deficit. Quite clever, if indeed the carbs are being burned off.
Except it was a legally available, over the counter drug intended for fat loss in the 30s and does actually have a good amount of data on it
Fair enough....
Many things were available in the 30's and before that really were crazy dangerous and not well suited for human treatment (back when they thought that having x-ray machines everywhere was totes awesome!). Also drug studies from that era had a rather gigantic number of issues with methodology which is why they are generally not regarded as great reference material without more modern studies as follow ups.
Other beloved relics that were great medicinal breakthroughs:
Chemical castration (fixed teh gayz)
Lobotomies (fixed teh everthingz)
Just saying. Prior legality is not a solid indicator of safety nor plentiful testing by reliable standards.
MrRippedZilla
Member
We clearly have different thought processes at work
I don't completely dismiss data due to assumed methodologically flaws stemming from the decade it arose from. I read the evidence and take into account any flaws when deciphering the strength of the results shown - dismissing it outright without any evidence to the contrary is a foolish approach to adopt.
I also wasn't placing any reliance on legal status as an indicator of safety. I was simply correcting your originally flawed assumption that DNP was never intended for use in humans. Nothing more, nothing less.
The FDA disagreed nearly the day it was established.... in the 1930's in point of fact. The also read the evidence (even by the dubious drug safety standards of the day, which was the reason the FDA was established) and ruled it "not fit for human consumption" in 1938.
Ergo, it was not intended for human consumption other than by snake oil salesman who would have also cheerfully intended tapeworms, cocaine, and carrying small chunks of plutonium around with you as "intended for human use".
Regul Toxicol Pharmacol. 2007 Jul;48(2):115-7. Epub 2007 Mar 31.
Dinitrophenol and obesity: an early twentieth-century regulatory dilemma.
Colman E1.
The only studies post 1938 have been animal studies because you know.... medical ethics are a thing... in most countries.
RodgerThat
New Member
Originally intended for humans yes.... But soon after development it was banned, possibly in record time. The only human use for DNP sanctioned by any government beyond I think 1940 was for the Russian army as a means to stay warm during long stints in extreme cold. With that said I have 20x250mg caps of DNP in my winter medical kit. I will never use DNP again short of that reason though because good DNP makes you boil.
OP please do not up the dose again until you've been on for weeks 4 days wasn't enough time to get use to it in your system and more isn't better, it's wreckless going on that train of thought
Flabbybutt
New Member
Oh, don't worry, I'll never take more than 500mg a day. 1000mg accumulation is enough. I don't want to creep towards those lethal doses.
MrRippedZilla
Member
Yea...again, I couldn't give 2 shits about the FDA's opinion on what is safe for me and what is not. The risk/reward ratio is, and always will be, a subjective matter.
I'm amused by the fact that you accuse everyone in the 30s of being a snake oil salesman and then decide to provide a paper written by an author who falsified statistics not in the 30s but in 2007
In that very paper Colman claims over 2,500 cases of cataracts and then references a paper by Horner. The Horner paper says NOTHING about "2,500 cases", it was a bullshit estimation by Colman with the calculations never explained.
Of course had Colman bothered to read Horner's 1941 paper he would know that the estimated number of reported cataract cases was 164/hundreds of thousands with an incidence rate of 1% or less. Maybe he did read it and couldn't be bothered to reference it because, you know, it doesn't fit in with the tone of the paper in general
I've used DNP many times over the past few years and have researched it pretty extensively - just in case that wasn't obvious already.
DonQKong
New Member
Have you ever tested its limits and died though lol
Help I used DNP and now I diedz!
I like how some peeps come out and share insights, like you, it's awesome how much there is left to learn about DNP. Well done
DQ
Lol, not if you're on DNP.
25 grams of carbs isn't going to do shit other than make you sweat on DNP, which is why you should take it to make sure it isn't fake crap.
Flabbybutt
New Member
Day 5: Another 250 mg down the hatch. Last night I slept well, but didn't sweat. My wife woke up hot and asked me why I was under the comforter. Still waiting for the heat and sweating to start. No weight loss to report this morning though. Although, on my first post, I reported being down two belt notches. But actually that second notch was tight. But yesterday, that second notch was loose, and I'm approaching the third notch. I guess there is no proof that this is due to Dnp, but still.
DonQKong
New Member
You won't lose much weight the first days as your body is drawing water to dilute the poison. You'll notice your skin gets more jiggly. You'll get that back 3-4 days after you stop doing it and your body suddenly drops the water weight. That's where stories like 'I woke up with a new six pack this morning, totally ripped abs' comes from.
But man, no sides, you must be made of cryptonite dude lol
But man, no sides, you must be made of cryptonite dude lol
Flabbybutt
New Member
Ya, must of been that clen. It desensitized me some how. Yesterday, I was at 750mg accumulation, and today, after my second dose, I'll be at 916mg accumulation. Surely, I'll feel it today. Either way, I'll keep truckn'
Flabbybutt
New Member
I opened up a cap. 
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That certainly looks like it to me. Careful, it stains like a motherfucker.
The FDA also banned ephedrine and claims marijuana has no medical benefits whatsoever even though the US Federal government owns a patent on marijuana treating hupercholesteremia.....
Flabbybutt
New Member
I just ate a whole grain roti naan, and 1/4 garlic Naan. Let's see if I feel heat
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