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Giant Semaglutide Thread (and other GLP-1 / GIP agonists)
- Thread starter Doodle
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HB_22
Well-known Member
Cagrilintide seems a good addition to any glp-1.
Started tirz 6 days ago at 2mg. Made me slightly nauseous on night 0 and carried over a little into the next day. Appetite suppression is absolutely insane, and so is the fullness effect. First 2-3 days I could get full by just smelling food. Managed to hit all my macro targets somehow(food in a blender) so far. Appetite came back today somewhat on day 6 so I pinned another 2mg. Currently nauseous as I'm typing this.
Going to probably do every 7-8 days in the future so I can get a refeed day in once a week. This stuff fucks.
Going to probably do every 7-8 days in the future so I can get a refeed day in once a week. This stuff fucks.
Cool. I’ll try that. What dose are people starting on with tirz? Do I keep tirz at 15?
yeah it's really hard to eat on tirz. It's highly effective and makes cutting easier because food just loses all appeal beyond its functional value
I find I still get hungry but I just get full super quickly.
Also high fat foods just don’t sit well. If I eat chicken and green beans I can finish 200 g chicken breast and feel full with no nausea. Fullness lasts a long time. If I were to eat the equivalent in a fatty food, even like lean ground beef, I get insane nausea.
I wonder if long term tirz will train people to eat cleaner out of fear of nausea lmao.
WilliamH.Bonney
New Member
Hope,
I would suggest increasing your dose instead of stacking compounds. You obviously tolerate tirzepatide well, so, stick with it. Don't make things more complicated than they need to be.
I use 21mg per week dosed at 6mg every other day. If you tolerate the single bolus dose you can stick with that. It's easier and cheaper. I've been sticking needles in myself for 20 years so it's akin to brushing my teeth for me.
I'll probably move to 25mg per week sometime this coming winter. Then on to 30 plus, but I'm experimenting for many reasons. If you're just after weight loss you'll hit a dose you can maintain indefinitely and be satisfied.
If a higher dose works for you, it works for you. Just don't move up too fast and stay aware of how you feel. If you experience anything abnormal, meaning anything outside of the typically stated unwanted effects, just go back down a step. However, just like previous doses, your body will acclimated itself in time.
Also, don't listen to the people saying one should come off of the drug and let your "system reset". There's absolutely zero evidence showing that the drug stops working or that your receptors down regulate.
Starting a weight training program would be ideal, of course. Non of us are getting any younger and muscle is important for metabolic health and longevity. These drugs will give you the rewards that you EARN. Much like other performance enhancing drugs, at first they work FOR you, but in time you need to work WITH them to reap all of the benefits.
You look great by the way! Good luck!
MaxROM
New Member
Using 2mg/vial from UGL Driada Medical.Started with 0.25 first week then uped to 0.5,stayed there for 5-6weeks and went up to 0.7 over 2 more weeks.So that's around 8 weeks now and I lost about 12kg with a deficit of around 700-1000kcal.Side effect none except maybe a bit of fatigue and probably little headaches here and there.
Since I tolerate it pretty good I fell in love with it, no food cravings what so ever and need to eat like 2 hands full to feel full af.
Only "contra" I got is the tolerance build up but I guess that's just normal for the kind of med.
Since I tolerate it pretty good I fell in love with it, no food cravings what so ever and need to eat like 2 hands full to feel full af.
Only "contra" I got is the tolerance build up but I guess that's just normal for the kind of med.
MrRobotbeeboop
New Member
Week 2 of UGL Triz @ 2.5mg weekly, my appetite is noticeably lower, but it did come back in the last days of week between doses. To be honest even after 2 weeks to showing my relationship with food was/is not the best. A lot eating to eat and typically not great foods. So I am optimistic not only will I lose weight but re-frame my relationship with food.
ForYourEyesOnly
Member
Quick question but I’ve been on Tirz for 4 weeks now at 2.5mg. Still feeling the effects of appetite suppression at 2.5 although not like the first couple doses. Should I continue at 2.5 until its effects diminish or begin the 5mg dosing (week 5) for a “greater” effect? For reference, I am a female and 160lb. I am also on 10mg Test P weekly which made me extremely hungry before starting Tirz.
WilliamH.Bonney
New Member
If you are using this strictly for weight loss, I would work up to the highest tolerable dose as quickly as possible. There is no benefit to staying at a lower dose and there is no trophy given to the person who stays on the lowest dose. Don't push it just to push it, but it sounds like you're listening to your body and are probably ready to move up.
explodingHeart
Member
For users for GLP1s, has it changed your behavior outside eating in any way?
Example:
www.healthline.com
www.nature.com
Example:
Ozempic and Alcohol: Could GLP-1 Drugs Help You Overcome Addiction?
From ending the desire to stop drinking alcohol to quitting smoking, people are claiming that GLP-1 drugs like Ozempic and Wegovy are helping them overcome a range of addictive behaviors.
www.healthline.com
- In testimonials shared online, some users claim they no longer feel the same desire for habits like smoking, drinking alcohol, and gambling.
Associations of semaglutide with incidence and recurrence of alcohol use disorder in real-world population - Nature Communications
Anecdotal reports from patients prescribed semaglutide describe a reduced desire to drink. Here, the authors show that semaglutide is associated with a 50%-56% reduced risk for both the incidence and recurrence of alcohol use disorder in real-world populations.
www.nature.com
My mom and I have been on it for over a year. I’m at 15, but my mom was able to stay on 5 the whole time. So it’s much cheaper for her.
Why? Since it's not a fat burner. I'd argue that it is better to increase frequency before dosage.
HB_22
Well-known Member
I doubt that going up to 30mg tirz/week is cheaper than staying at 10 or 15mg and implement 1mg of reta, as reta is also boosting metabolism helping to lose way more weight in the long run than increasing tirz ever could.
roofer22
Well-known Member
Both my wife and I stayed at a low dose as long as it works both with great results. If something is working to your satisfaction why bump it up? I always believed in the lowest effective dose.
WilliamH.Bonney
New Member
It certainly seems to be. There are lots of fun things happening in fat with Tirzepatide.
WilliamH.Bonney
New Member
I didn't tell her to use 30mg. As far as the rest of your comment, opinions vary.
Liter O' Test
Member
Anyone able to give me a quick run-down on the differences between different GLP-1s?
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