MESO-Rx
Anabolic Steroids
Giant Semaglutide Thread (and other GLP-1 / GIP agonists)
- Thread starter Doodle
- Start date
phenominal34
Member
What will you start back out with for dosage of Tirz if recently on the Sema ?
Rido
Subscriber
You should take a 3 month break.... You can't bounce between one GLP agonist to another. It's working off the same receptor. Its like a cross tolerance between Vicodin and oxycodone.(speaking from a medical perspective)
I was thinking about doing 5mg at first. I was at 7.5mg before my order got delayed.
That makes sense. I think I’ll try that. Thank you
I started on the sema again only because my tirze was having issues getting here. I was afraid to gain some weight back after reading things in the Facebook and Reddit groups.
I feel better now about taking a break.
Rido
Subscriber
If you want to. I would advise a short bulk. Use the hunger to your advantage
Tirzepatide is not just a glp1 agonist. It is also a GIP agonist.
Squaresky2
New Member
I agree with Cridi. Great advice on the bulk while you wait to change meds.
Background: have been on pharma Ozempic and mounjaro plus also both UGL versions. Even tried pharma Victoza
You need a 3 month break between switching medications. They do loose their effectiveness over time. By pharma design? So they can make the next biggest, better drug? Because our body adapts to the over stimulation of the GLP1 ? Who knows but a cycle off helps.
Background: have been on pharma Ozempic and mounjaro plus also both UGL versions. Even tried pharma Victoza
You need a 3 month break between switching medications. They do loose their effectiveness over time. By pharma design? So they can make the next biggest, better drug? Because our body adapts to the over stimulation of the GLP1 ? Who knows but a cycle off helps.
T&H
Well-known Member
I believe it's just the bodies ability to adapt to what seems like everything. Even DNP requires an increase about 3 weeks in due to adaptation, and a suggested break after a cycle.
Squaresky2
New Member
Agreed. Defense mechanism. You can only grow so much muscle. You can only loose so much weight. Etc etc
I have been taking L Carnitine with my semaglutide. I started taking 0.25 and then raised it but because of injectable L Carnitine, I still have some appetite suppression after missing my dose for 3 days. Originally I wanted to do this as a cut but I am still losing weight at a slower weight due to adding muscle.
So far, I have been taking semaglutide for a month while being on TRT and I have went from 340 to now 314. I got on TRT and originally recompositioned after health problems that I went through and now I hope to see what I look like at my weight where I was before as I definitely added a lot of muscle.
So far, I have been taking semaglutide for a month while being on TRT and I have went from 340 to now 314. I got on TRT and originally recompositioned after health problems that I went through and now I hope to see what I look like at my weight where I was before as I definitely added a lot of muscle.
Do either of these seem to limit strength/performance, other than the obvious drop from simply weighing less? Thinking of how Metformin reduces hypertrophy via mTor, etc. Mostly wondering if it would be useful for a power athlete to utilize when dropping weight classes.
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Iron_Yuppie
Well-known Member
That is a price so cheap as to raise obvious alarm bells. QSC, which as best I can tell is the cheapest place on the planet of Earth to buy this stuff, is ~3.3x more expensive than what you’re being offered. I would be highly skeptical of what you’d be getting for that price.
HB_22
Well-known Member
It's useless anyway. You need a very, very expensive machine to turn that raw powder into freeze dried powder and to mix it with manitol(?) or something. It's a waste.
Qingdao Sigma Chemicals
Subscriber
It's the market prices for raw. Not surprising. We get it cheaper than that.
Instead of going to 1.7 on dosage for Semaglutide, I think I'll continue pin .5 3xs week w my HCG and see if it overlaps well w minimal sides and max effects. I feel like the 1mg split 2xs weekly isnt as effective as where it started, could just be a rough couple of days though. I'm def still in deficit but choices popping up aren't as optimal that I usually never engage in.
Iron_Yuppie
Well-known Member
So you believe the price he was offered is fair for legitimate product? It seemed far too low to me which is why I am skeptical.
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