HGH and Heart Rate During Cardio

Nine of the patients in placebo arm were in treatment with ACE inhibitors, whereas seven of them where on B-blockers; in the GH group instead, eight patient were on ACE inhibitors and nine on  B-blocker treatment. All patients completed the 3-month course of treatment; those in the GH group did not report side effects. There was no change in body weight, body composition, or hemoglobin concentration after GH or placebo. The serum IGF-I level significantly increased (near doubled) in all patients treated withGHand remained stable in the placebo group. The clinical status improved after GH, as indicated by the significantly decreased NYHA functional class, whereas it remained stable in the placebo group. GH did not affect the resting heart rate; the mean arterial pressure was significantly lower due to a reduction in both systolic and diastolic arterial pressure. There was no change in heart rate or in arterial blood pressure after placebo.

More people in the GH group were on beta blockers. This may have offset the GH difference compared to placebo. The sample sizes are too small to request a subgroup analysis but maybe a small effect.
 

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