Insulin Does Not Increase Muscle Protein Synthesis Rate

[Dr JIM]

Insulin is well known to reduce protein breakdown and can lead to a higher overall net protein balance - helping to increase muscle growth.

The point of the review article Dr S posted is that there is NO evidence Insulin itself exerts an anabolic benefit on SKM.

Because if that's the case it's one heck of a leap to assume it's use in a cycle improves, enhances, induces or accelerates muscle hypertrophy.

Thus while it's obvious insulin does exert a certain degree of anti-catabolic activity does NOT mean "it's inclusion in a cycle" affords the user ANY benefit. Why is that? Bc the amount of insulin needed to restrict catabolism is already produced endogenously and no net gain is achieved thru supplementation. Why is that? Bc supplementation reduces endogenous insulin production in a proportional manner!

That's one huge difference bt insulin and TT and GH both being relatively specific, compared to insulin, for their SKM anabolic properties. That's bc the endogenous production of both of these drugs is relatively small and exceeding ones baseline production is relatively easy and with limited adverse effects, the same most certainly can NOT be said for insulin.

So how much insulin should be used to improve anabolism thru "a reduction of catabolism" obviously that would depend upon one's diet and basal metabolic demands but somewhere around 30 to 50 units daily!

How many BB are using those doses, close to NONE. Just as important what type of insulin affords the greatest benefit, Humalin R, Humalin NPH, Lente or Ultra Lente?

How much and how long would someone have to use insulin before "insulin resistance" occurred and does the development of HR predispose the user to DM?

For these reasons and many others I don't believe there is ANY reason one can justify the use of insulin as an adjunctive anabolic agent. The risks FAR outweigh any potential benefit and apparently the WADA concurs, whom have never even considered insulin (above a certain level) a potential PED.

 

[alphastrength50]

I find it fucking HILARIOUS how the only one I know for sure is a MD Doctor and the OP is not arguing back amd forth with you "Doctors" just saying nevertheless this is quite the entertainment and I find it extremely hard to believe that you Medical Doctors have this mucj free time to converse on thos forum. Just sayin

 

[Dr JIM]

I find it fucking HILARIOUS how the only one I know for sure is a MD Doctor and the OP is not arguing back amd forth with you "Doctors" just saying nevertheless this is quite the entertainment and I find it extremely hard to believe that you Medical Doctors have this mucj free time to converse on thos forum. Just sayin

Since I have an office, hospital practice, frequent a analytical lab at least twice weekly and post on Meso to ensure boredom does not vanquish my interest in life, perhaps you would benefit most from a seminar on improving and/or diversifying those time managements skills of yours fella, less monotony plague your zest for living.

In other words I do what I do because I enjoy it, and because I enjoy it I make time to do it. Sound familiar? Ever heard someone say they "don't have the time to work out", yep I do that also!

Just saying

 

[CensoredBoardsSuck]

Hell, Obama plays 3 rounds of golf a day and he still has time to be the POTUS.

 

[zoot494]

Since I have an office, hospital practice, frequent a analytical lab at least twice weekly and post on Meso to ensure boredom does not vanquish my interest in life, perhaps you would benefit most from a seminar on improving and/or diversifying those time managements skills of yours fella, less monotony plague your zest for living.

In other words I do what I do because I enjoy it, and because I enjoy it I make time to do it. Sound familiar? Ever heard someone say they "don't have the time to work out", yep I do that also!

Just saying

hahaha this is pretty much perfect. Time management is all it takes. Just because he's a doctor and I'm a med school student that doesn't mean we sit behind a desk/are doing clinicals 24/7. Medicine is my passion and applying it is my job (and applying it on myself is my hobby ) but that doesn't mean it consumes every waking moment of my life. Plus, it's not like it takes hours to even find this information. When you deal with this stuff on a daily basis you know where to look.

I think it's also interesting though as to how there are many different beliefs throughout the field. Same science. Same studies. Different conclusions. Fun stuff.

 

[MrRippedZilla]

I find it fucking HILARIOUS how the only one I know for sure is a MD Doctor and the OP is not arguing back amd forth with you "Doctors" just saying nevertheless this is quite the entertainment and I find it extremely hard to believe that you Medical Doctors have this mucj free time to converse on thos forum. Just sayin

And exactly where did I claim to be a medical doctor?? LOL I suppose I should take this as a compliment

Me & Dr Jim were not having an argument - it was an intelligent debate that was clearly way over your head. I have a lot of respect for him and certainly appreciate the time he took to justify his opinion.

It amuses me that debating the potential applicability of a review/study seems so hilarious & farfetched to you.
You realise that this happens all the time among intelligent human beings right?

 

[alphastrength50]

Dr. Jim if in all reality can I shadow you? Im a med student and am looking forwardto appreciate the diversity of Medicine

 

[zoot494]

Alpha, how does a med school student like you not have the ability to use punctuation or grammar? Seriously, I'm curious.

And at RippedZilla he was referring to Dr Jim saying Jim wasn't a real doctor and the OP is a real doctor.

 

[Dr JIM]

Dr. Jim if in all reality can I shadow you? Im a med student and am looking forwardto appreciate the diversity of Medicine

Sure, but you will never even see my shadow if you don't first improve your time management skills and learn how to write a full and complete sentence which others can follow and understand

 

[alphastrength50]

lol u silly guys im on taptalk and my ohones sucks

 

[alphastrength50]

Alpha, how does a med school student like you not have the ability to use punctuation or grammar? Seriously, I'm curious.

And at RippedZilla he was referring to Dr Jim saying Jim wasn't a real doctor and the OP is a real doctor.

easy Zoot.never clearly said he wasnt just said its hardto believe lol what year are u? im on the Cardiology path at an allopathic school. its always great to see other physicians/future physicians on here

 

[MrRippedZilla]

And at RippedZilla he was referring to Dr Jim saying Jim wasn't a real doctor and the OP is a real doctor.

He said "doctors" - plural.

Of course this could be yet another example of his poor grasp of the English language but I like to look at the glass half full and assume he thought we were also doctors

 

[alphastrength50]

He said "doctors" - plural.

Of course this could be yet another example of his poor grasp of the English language but I like to look at the glass half full and assume he thought we were also doctors

i can clear upyour confusion here. i was not implying you so relax lol and if ur not a doc even more reason to laugh it offrelax man

 

[Dr JIM]

easy Zoot.never clearly said he wasnt just said its hardto believe lol what year are u? im on the Cardiology path at an allopathic school. its always great to see other physicians/future physicians on here

The "cardiology path", come again?

 

[zoot494]

Ahh, I'm not really a big fan of homeopathic medicine. I'm not going to get into a war (which will happen if I express my views on that) on this forum so I'll just leave my statement at that.

I'm only a year in, but planning on becoming a neurosurgeon with a specialty in spinal reconstruction.

p.s. I think you pissed off Jim lol

 

[alphastrength50]

oh ive pissed off Jim several times. Yes our school has. a Cardio accelerated path where we shadow and follow Cardiologist whether intervention or not its interesting and there r more assignments

 

[alphastrength50]

Ahh, I'm not really a big fan of homeopathic medicine. I'm not going to get into a war (which will happen if I express my views on that) on this forum so I'll just leave my statement at that.

I'm only a year in, but planning on becoming a neurosurgeon with a specialty in spinal reconstruction.

p.s. I think you pissed off Jim lol

Im assuming your doing a DO? i have a family friend finishing neurosurgery residency . he/she had the highest Board score in history at our school.

 

[Dr JIM]

oh ive pissed off Jim several times. Yes our school has. a Cardio accelerated path where we shadow and follow Cardiologist whether intervention or not its interesting and there r more assignments

So and what year are you in medical school such that a MS has already decided what their speciality will be? And what does doing a DO mean? No and on second thought, you shall not shadow me, stick with cardiology

 

[alphastrength50]

So and what year are you in medical school such that a MS has already decided what their speciality will be?

havent decided specialty yet Jim man. there r primary care tracks friends are doing just out of sheer interest amd curiousity dont worry about my year lets just say ill have to make a new accountfor my new name sometime soon with two letters that u haveurself

 

[Dr JIM]

Worry are you joking I just inquired about your MS year, I didn't know that was the equivalent of protected information or what gives?

Also based on your script it seems your either an FMG or a attending a nonUS based MS. I'm guessing India right?