MK-677

MK677 has been an excellent addition to my off season PEDs. It causes me serious water retention, especially ankle swelling but the pumps, fullness and strength increase is impressive.

It definitely is not a good prep choice (for me) as it does not assist in the fat loss department like exogenous GH does and when combined with carbs above 250g daily it causes me mid section bloating also. Basically it turns me into a water buffalo.

My bro science speculation is that it causes a focused water retention reaction in the intestinal region. I don't know if that is related to it being used orally or that it's contributed to the GH/IGF elevation it creates. Either way, when I stop it's use the swelling goes away and my waist is right back to the normal size.

I just had bloods drawn while using 3ius of GH pre-wo with insulin and 50 mgs of MK677 ED. I'm curious to see the IGF numbers because the physical responses I've been seeing/feeling are pretty strong. I've previously seen a jump of 70 in IGF when added on top of exogenous GH.

I've been experimenting with MK677 because I like the idea if using less GH but having the elevated IGF numbers in the off season for adding size. MK677 has fit into that slot nicely. Plus, it's cheaper in total cost to combine GH and MK677 than running a higher dose of GH.

I already know what this particular GH does for me at 3 ius number wise from my last draw so any increase I see in IGF will be all MK677. Naturally, I'll post up my blood work for everyone once I get it back.
 
MK677 has been an excellent addition to my off season PEDs. It causes me serious water retention, especially ankle swelling but the pumps, fullness and strength increase is impressive.

It definitely is not a good prep choice (for me) as it does not assist in the fat loss department like exogenous GH does and when combined with carbs above 250g daily it causes me mid section bloating also. Basically it turns me into a water buffalo.

My bro science speculation is that it causes a focused water retention reaction in the intestinal region. I don't know if that is related to it being used orally or that it's contributed to the GH/IGF elevation it creates. Either way, when I stop it's use the swelling goes away and my waist is right back to the normal size.

I just had bloods drawn while using 3ius of GH pre-wo with insulin and 50 mgs of MK677 ED. I'm curious to see the IGF numbers because the physical responses I've been seeing/feeling are pretty strong. I've previously seen a jump of 70 in IGF when added on top of exogenous GH.

I've been experimenting with MK677 because I like the idea if using less GH but having the elevated IGF numbers in the off season for adding size. MK677 has fit into that slot nicely. Plus, it's cheaper in total cost to combine GH and MK677 than running a higher dose of GH.

I already know what this particular GH does for me at 3 ius number wise from my last draw so any increase I see in IGF will be all MK677. Naturally, I'll post up my blood work for everyone once I get it back.


Do you get the weakness in legs?

Ive stop/started mk-677 various times over the years and everytime i restart for about the first 2 weeks i get very weak in the legs, or at least a feeling of such, but once i get them warmed up i can lift usual numbers.
 
Do you get the weakness in legs?

Ive stop/started mk-677 various times over the years and everytime i restart for about the first 2 weeks i get very weak in the legs, or at least a feeling of such, but once i get them warmed up i can lift usual numbers.
Weakness in my legs? Nope. I've never heard of that. If anything I get stronger by the week.
 
Do you get the weakness in legs?

Ive stop/started mk-677 various times over the years and everytime i restart for about the first 2 weeks i get very weak in the legs, or at least a feeling of such, but once i get them warmed up i can lift usual numbers.

Are you meaning lethargy? Im into week 2 of mk and my legs feel like im walking around in cement shoes! But strength, fullness and pump has come on.

Was going to wait till fall to start up mk, but thought I'd add it in to my bpc157 and tb500 rehab efforts. All my research has been coming up that all three compounds should work synergistically.

Ive never done gh before, so the idea of my own body ramping up production sits a little better with me.
 
I'll post my actual lab work tomorrow.

My last IGF test was done in March and with 3uis GH ED fasted in the morning I had a 286 (up from my natural 171). I posted that test in the Alibaba Gh thread.

I took a 6 week break from GH in May thru late June and started back with the same batch at 3ius pre-wo with insulin July 1st combined with 50 mg of MK677 (25mg a.m. and 25mg p.m.). Had bloods pulled 7/11 and my IGF was at 433.

So in a nut shell 3uis of generic GH plus 50 mgs of MK677 got me to 433 when the same GH at the same dose only got me to 286 a few months ago.

Currently running 750mg Test C and 400mg of Mast. During the previous bloods I was 1000mg sust, 600 Mast and 400 Tren A but I was in prep then also.

I've adjusted down to 25mgs of MK at night before bed due to the water retention issues at 50 mgs but the GH dose is the same. I'll be adding in a few things soon and pushing for more size since I'm now entering my true bulk season.

I'll pull bloods again in a few weeks to see where I am since dropping down to 25mgs from 50. Naturally, I'll post the results when I get them.
 
I'll post my actual lab work tomorrow.

My last IGF test was done in March and with 3uis GH ED fasted in the morning I had a 286 (up from my natural 171). I posted that test in the Alibaba Gh thread.

I took a 6 week break from GH in May thru late June and started back with the same batch at 3ius pre-wo with insulin July 1st combined with 50 mg of MK677 (25mg a.m. and 25mg p.m.). Had bloods pulled 7/11 and my IGF was at 433.

So in a nut shell 3uis of generic GH plus 50 mgs of MK677 got me to 433 when the same GH at the same dose only got me to 286 a few months ago.

Currently running 750mg Test C and 400mg of Mast. During the previous bloods I was 1000mg sust, 600 Mast and 400 Tren A but I was in prep then also.

I've adjusted down to 25mgs of MK at night before bed due to the water retention issues at 50 mgs but the GH dose is the same. I'll be adding in a few things soon and pushing for more size since I'm now entering my true bulk season.

I'll pull bloods again in a few weeks to see where I am since dropping down to 25mgs from 50. Naturally, I'll post the results when I get them.
Damn brother those are some bad ass results ! Thanks for testing !

I wanna give mk677 a run so i can cut back my gh some , but water retention is my biggest concern . Its already bad enough at 6-7iu :oops: ... does the water retention ease up some once your body acclimates to the mk677 similar to gh , or does it stay pretty consistent until you discontinue use? This definitely is peaking my interest in the compound ..
 
Damn brother those are some bad ass results ! Thanks for testing !

I wanna give mk677 a run so i can cut back my gh some , but water retention is my biggest concern . Its already bad enough at 6-7iu :oops: ... does the water retention ease up some once your body acclimates to the mk677 similar to gh , or does it stay pretty consistent until you discontinue use? This definitely is peaking my interest in the compound ..

For me it stayed the whole time I used it, and dissipated within a week of coming off. Worth noting I was trying to put on weight at the time.

Some people say the water weight dials back after a few weeks, so guess it can be different person to person. There are a lot of variables of course.
 
For me it stayed the whole time I used it, and dissipated within a week of coming off. Worth noting I was trying to put on weight at the time.

Some people say the water weight dials back after a few weeks, so guess it can be different person to person. There are a lot of variables of course.
Yeah im sure it depends on your diet alot . Thats what worries me is gh in general turns me into a water buffalo . I can run anything gear wise no real bloat or blood pressure issues , but the second i start pushing the gh up I bloat up and have to fight my bp back down into range .
 
My experience with Mk-677:
I've never used gh so I have no way to compare it, however, what I can say is this: Mk-677 combined with aas (I've tried it with both test/deca and test/tren) is the greatest bulking compound i've ever experienced. Massive water gains within the first week, (10lbs+) and then the scale slowly creeps up with actual tissue gains. Massive strength gains. I basically go up 100+ pounds on deadlift within 10 days of starting. I do actually believe mk-677 could be utilized in a cutting phase, definitely in a recomp, as I do lose bodyfat, it's just not immediately noticeable due to water retention. This is assuming of course that the appetite increase does not effect you as much as some others. Coming off of mk, I was the most shredded I have ever been. I was on a blast of 600 test e + 350 tren ace, gained a solid 5lbs after water retention subsided with veins bulging out of my abs and back. Just my $.02
 
Damn brother those are some bad ass results ! Thanks for testing !

I wanna give mk677 a run so i can cut back my gh some , but water retention is my biggest concern . Its already bad enough at 6-7iu :oops: ... does the water retention ease up some once your body acclimates to the mk677 similar to gh , or does it stay pretty consistent until you discontinue use? This definitely is peaking my interest in the compound ..

For me the water retention is always there somewhat when MK is used (mostly ankle swelling) but it’s most certainly made worse by increasing the dose.

At 25mg ed it’s not too bad but at 50mg ed spilt dose I’m easily 5-8# heavier with water eating the exact same food. Granted the fullness is unbelievable but you feel like a balloon animal.

My abdomen swells also. All water, but I don’t care for the Dad look or how it makes me feel. The llower back pumps at 50mgs are almost impossible to train with. But strength is increased quite a bit.

Most of us use GH when cutting so with a prep diet the water issues are almost non-existent. I don’t even get swollen ankle when I’m running GH on prep. MK is a different animal. O
 
Damn brother those are some bad ass results ! Thanks for testing !

I wanna give mk677 a run so i can cut back my gh some , but water retention is my biggest concern . Its already bad enough at 6-7iu :oops: ... does the water retention ease up some once your body acclimates to the mk677 similar to gh , or does it stay pretty consistent until you discontinue use? This definitely is peaking my interest in the compound ..
Ever try taking a diuretic? Something that decreases mineral retention might help.
 
Ever try taking a diuretic? Something that decreases mineral retention might help.
Yeah ill take ditide once in a while , but i also take telmisartan so I try to only use diuretics sparingly because they can have adverse effects taken together. Maybe ill pick up a natural diuretic like dandelion root or something and give that a try. It really only happens when i push gh up to 6+iu , but thats why ive always been a little sketched to try mk because its pretty synonymous with bad retention.
 
At 25mg ed it’s not too bad but at 50mg ed spilt dose I’m easily 5-8# heavier with water eating the exact same food. Granted the fullness is unbelievable but you feel like a balloon animal
Im going on an actual cruise dose of T here in the next few weeks . I think I might throw it in then when my water retention isnt gonna be to bad from a high dose of T . Start at like 12.5 and taper up until I feel the bloat coming on , see if i cant find a sweet spot . Thanks for your insight bro , i cant wait to see the rest of your results !
 
Yeah ill take ditide once in a while , but i also take telmisartan so I try to only use diuretics sparingly because they can have adverse effects taken together. Maybe ill pick up a natural diuretic like dandelion root or something and give that a try. It really only happens when i push gh up to 6+iu , but thats why ive always been a little sketched to try mk because its pretty synonymous with bad retention.
I'd like to start taking telmisartan. Read here that there were some good things to achieve from taking it besides blood pressure.
I don't hold water easily and the only time I did I used a diuretic cause my E2 was high, I was on mk677 and a ton of GH. I heard natural stuff works decently. I used natural stuff for my blood pressure and that always helps noticeably.
 
I'd like to start taking telmisartan. Read here that there were some good things to achieve from taking it besides blood pressure.
I don't hold water easily and the only time I did I used a diuretic cause my E2 was high, I was on mk677 and a ton of GH. I heard natural stuff works decently. I used natural stuff for my blood pressure and that always helps noticeably.
The biggest thing ive noticed with telmisartan is that its had a really nice recomping effect on my physique. I dont know the exact mechanism of action for its fat burning effects , but it absolutely has that effect. Its something you notice over a few months though. It's not dramtic at first so dont expect it to be crazy , but youll slowly see a nice thinning out effect over time , atleast I have .

Plus as far as bp meds go its a pretty safe drug with very few interactions or side effects . The one down side is it takes about 3-4 weeks before you see your bp make any dramatic changes, but if your just a little out of range like I was its not a big deal.
 
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Im going on an actual cruise dose of T here in the next few weeks . I think I might throw it in then when my water retention isnt gonna be to bad from a high dose of T . Start at like 12.5 and taper up until I feel the bloat coming on , see if i cant find a sweet spot . Thanks for your insight bro , i cant wait to see the rest of your results !

Glad to pass it on brother. MK 677 is intriguing to me so I've continued to experiment with it. It's shown me several times a legit IGF increase even while on GH for extended periods of time which is pretty awesome since exogenous GH suppresses your natural levels.

It's definitely a cheaper alternative than just running more GH if the focus is to push up IGF levels. Unfortunately, I personally don't see the full range of benefits compared to just using higher doses of GH but then again my use has been restricted to off season cruising and full on bulking periods.
 
I'll post my actual lab work tomorrow.

My last IGF test was done in March and with 3uis GH ED fasted in the morning I had a 286 (up from my natural 171). I posted that test in the Alibaba Gh thread.

I took a 6 week break from GH in May thru late June and started back with the same batch at 3ius pre-wo with insulin July 1st combined with 50 mg of MK677 (25mg a.m. and 25mg p.m.). Had bloods pulled 7/11 and my IGF was at 433.

So in a nut shell 3uis of generic GH plus 50 mgs of MK677 got me to 433 when the same GH at the same dose only got me to 286 a few months ago.

Currently running 750mg Test C and 400mg of Mast. During the previous bloods I was 1000mg sust, 600 Mast and 400 Tren A but I was in prep then also.

I've adjusted down to 25mgs of MK at night before bed due to the water retention issues at 50 mgs but the GH dose is the same. I'll be adding in a few things soon and pushing for more size since I'm now entering my true bulk season.

I'll pull bloods again in a few weeks to see where I am since dropping down to 25mgs from 50. Naturally, I'll post the results when I get them.


Mighty interesting!

rHGH is believed to blunt natural pulses for at least 24h

That means MK677 could still force that pulse. Wow
 
Mighty interesting!

rHGH is believed to blunt natural pulses for at least 24h

That means MK677 could still force that pulse. Wow
That is the most interesting part for me and I've seen this happen each time I've used MK677 with GH. My first "experiment" was after being on GH for 5 months at 5uis ED and I still saw a jump of 70 in IGF.

MK677 seems to have the ability to promote a higher natural GH pulse even if your natural levels should theoretically be suppressed. It's some very interesting results.
 
That is the most interesting part for me and I've seen this happen each time I've used MK677 with GH. My first "experiment" was after being on GH for 5 months at 5uis ED and I still saw a jump of 70 in IGF.

MK677 seems to have the ability to promote a higher natural GH pulse even if your natural levels should theoretically be suppressed. It's some very interesting results.
May have missed it but are you taking your full daily dose before sleep, or another time?
 
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