I am not sure they actually had proven that LH is maintained via short acting NATESTO.. rather was hypothesized and LH was halved via natesto... 23 people or less and its very possible u get all the downsides of gel... dont think they even compared gel LH FSH of gel vs natesto.... also need to consider timing as folks who use gel in morning likely preserve similarly to (although ive never dug up any data, and natesto sample size are small for that purpose) that is to say, dont trust natesto, they are a SKETCHY company, folks complain of crystallized product and somehow only some folks are able to return it as skeleton crew who ALL work from home and they contract out the actual manufacturing and appear not care too much about the QC as prob keeps liability to a min to them... infact has been recalled due to improper TOTAL levels in the jar, never mind random dosing with large crystals.. 3 doses of natesto has half life of 10min to 90min each dose, so at least ~hr of high T up to 5 or even 9+ hrs, and gel I think is 10-12 hrs or so? SOO much variability that I think SOME people it may help preserve a little better but depends how fast it lasts in your metabolism and if 1.5-2 hrs with lower T is enough for body to kick in LH? and enough LH produced in the small time to keep testicle going??? I dont know, but id just be wary of natesto if your goal is preservation.... some guys makes them feel great, appreciate that its less anabolic less affect on hemocrit compared to injections at least...
Def would love to see unbiased testing about LH hormone with short acting TNE.... im sure more will come after natesto looses patent and folks can get generic in 4-5 years.
Acerus literally has 1 guy working from home for usa and canada that when called is very clear is home based and forgets to plug in microphone etc even when asked repeatedly to do so lol than says oops and same issue the next time when trying to get none crystallized product.... they are highly sketch and appear IMO here just to make a quick buck(based on there biz model of PO Box no real office etc) and know they cant get taken off the market if guys loose sperm count or LH...
makes sense forsure but I would imagine that front loading vs 3Xday dosing would allow best LH preservation.. its also possible If absorb TOO fast ur levels skyrocket and while I am not sure mechanism one can imagine surprises LH even when TT drops to baseline... esp as we know it takes more than a few hrs of lh to produce sperm/natural production.
for me testicle pain from mostly 1X a day of natesto with odd time taking half dose for second one a day... still im sure better than injections esp 2xweek injections for preservation, but as always, skeptical... ESP as majority of the product comes crystallized so obv get major doses when take a 6mm long crystal...