Timing is important depending on your dose and goals. If you are taking 2iu for anti aging timing prob doesn’t matter, if you are taking a higher dose it’s preferred in the morning because at night your pituitary gland is naturally producing HGH during sleep so people “say” it’s slightly more beneficial first thing when you wake up.
Also should be 1-2 hours away from food.
Then you can be at a higher dose of let’s say 8iu which at that point it’s best to split am/pm 4iu which then doesn’t matter the timing persay