iris
Well-known Member
Wouldn't that be part of a routine hormone panel, though?
MESO-Rx
Anabolic Steroids
MESO-Rx Sponsor Opti USA DOMESTIC - HGH, INJECTABLES, TABLETS, PEPTIDES, & MISC
- Thread starter Opti
- Start date
readalot
Member
You'd need to understand how your SHBG has changed over time. All else being equal (which it ain't), SHBG will set your Total T for a given weekly dose. Hence if your "multiplier" has changed over time, that's one place to look.
A simple experiment to demonstrate is run constant dose of Test and do a stint of oxandrolone or stanozolol. SHBG will drop and so will Total T while free T stays about the same.
SHBG will also drop over time for those using exogenous androgens consistently.
Make sure you are using LCMS assay for Total T. No interference with other androgens.
My doctor ordered metabolic panel, cbc, total test, e2, tsh, GGT, CRP. A1c, lipids. Its not an endocrinologist so they don’t typically go in depth on sex hormone testing.
Ghoul
Well-known Member
Testosterone metabolism can vary greatly from one individual to another. One factor, for instance, are certain genetic mutations.
There's a genetic test that can identify these factors. It's $1500+ last I checked.
Here's one of the rare looks into this condition:
Genetic Polymorphisms Related to Testosterone Metabolism in Intellectually Gifted Boys - PMC
Prepubertal testosterone levels are lower in intellectually gifted boys. The aim of this pilot study was to analyze potential genetic factors related to testosterone metabolism in control and gifted boys. Intellectually gifted (IQ>130; n = 95) and ...
pmc.ncbi.nlm.nih.gov
That’s something I’ve been curious about the lcms. Would other androgens make the total lower?
readalot
Member
If you wanted to get to bottom of this just pull TT by LCMS and SHBG. You could order FT using ED+LCMS but shortcut using Vermeulen calculated FT about as good.
Of course you'd have to know where your SHBG used to sit back when "multiplier" was higher.
There are quite a few factors that are known and probably even more unknown things that affect one’s testosterone levels score. Timing, diet deficit, saturated cells, carrier oil, other aas in combination, etc
Hell, when I pick up my prescription testosterone from the pharmacy if they hand me the brand West Ward I absolutely refuse to take it and will hand it right back to them. Unsure why but it gives me pip and my T score is at a 4-6x multiplier when I take it. Other than that I’ve seen my score significantly lower when in a deficit.
If you have access to a pharmaceutical testosterone maybe try that to compare and see if it makes a difference. Most pharma testosterone is in cottonseed oil and hell maybe that will change your score. Most say gso and cso are nearly identical. I truly believe that’s bullshit. It’s why I actually am using Opti’s test cyp for my trt currently. His gso is smooth where every brand I’ve used with cso leaves a small lump and the oil needs warmed to even pin it.
readalot
Member
Direct interference with IA assay would inflate TT while other androgens like 17-aa would acutely decrease SHBG (via liver) and hence lower TT. In short it's complicated depending on the other androgen. That's why it pays to cover all the moving parts and of course very few really care to do it. Best wishes and great questions.
Thank you I’ll order these from Marek. My reason for posting is not to imply the source isn’t reputable. The easiest scenario for me would be the gear is underdosed I switch and move on but my guts been telling me it’s deeper than that so I appreciate the input.
readalot
Member
And other great points by B Ware. The nitty gritty details on what determines your free T vs dose comes down to (1) clearance and (2) volume of distribution. Together they set your apparent elimination rate constant. If you search on here @Elvis755 there's a bunch of posts gathering dust (or see Excelmale where there's a lot of detail posted).
thinksteroids.com
Search results for query: Clearance
thinksteroids.com
AlexDavis43
Member
Before we go down the rabbit hole, if you have any untapped vials see if Opti will reimburse you to send one for testing.
Sagnastymuscle
Member
most recent order. Came pretty fast less then 7 days got one of the pharma kits of Hcg , I will be coming down to trt for my gland removal I will be logging that when it gets scheduled and I’ll try to get pics of the surgery and size of the glands
Pulpfiction
Member
How are you liking his blue tops? I just started his blue tops a month ago
Sagnastymuscle
Member
I love the way I look and feel on them very hungry CTS is mild and sleep in amazing
Ateam2023
Well-known Member
i wish hgh made me hungry ,
Pulpfiction
Member
That’s awesome, I’m super hungry also I don’t have CTS though I’m only running 3.5 iu. Sleep is a little throwed off so I started pinning in the am instead of pm. Switched to OPTI a month ago and seems to be best decision I’ve made in a while
I don’t get better sleep, cts or hunger from hgh. The only major side I ever had was from tp blacktops and I held a ton of water. That was it.
AlexDavis43
Member
Thought you were a former fatty currently maintaining an impressively low BF. Sure you want to put that at risk? Or just stay ripped for a while
AlexDavis43
Member
No effects on sleep or hunger from hGH. Got some CTS early on when I ramped up too fast and/or didn't know my lifestyle triggers for side effects from hGH (high salt & carb meals, inadequate hydration & cardio, etc).
AlexDavis43
Member
I thought holding water was a contributing factor for CTS. Perhaps it's more complicated.
Similar threads
