Avanafil Janoshik lab test
Avanafil is used to treat male
sexual function problems (impotence or erectile dysfunction-ED) like
Tadalafil and
Sildenafil.
In combination with sexual stimulation, avanafil works by increasing blood flow to the penis to help a man get and keep an erection.
It's famous and know in the name of
Spedra
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DOSAGE:
100mg 30 min before sex
Avanafil compared to Sildenafil?
Avanafil is a much faster treatment than Viagra — it can take as little as 20 minutes to take effect. It is normally recommended that you take one Avanafil around 30 minutes before sex (and for some men, it can work as quickly as 15 minutes after consumption, particularly if you take it on an empty stomach).
Viagra, on the other hand, needs to be taken one hour before sex as it will not work before then.
The only exception to this is if you take Avanafil on a full stomach after a large meal — in which case it can take as long as 90 minutes to work.
Does Avanafil last longer than Viagra?
In this case, it’s a draw between the two medicines. Both of these ED treatments last a similar amount of time — approximately 4-5 hours.
It’s worth noting that this doesn’t mean that you will maintain an erection for this amount of time, but that your ability to achieve and maintain an erection will increase during this time.
Janoshik lab test:
Code:
https://janoshik.com/tests/29315-Avanafil_XZJEHIMDMBU8
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Impurities?
Janoshik comment:
"we did some extra work out of scientific interest and identified the major impurity too ( see comment ) - manufacture leftover. Feel free to share my email and the image attached"
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Identification, synthesis and characterization of avanafil process impurities and determination by UPLC
Code:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8985152/
Imp-A is named (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid, which is the intermediate 6 (M6) in the synthetic route of avanafil