Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic

[Mayne]

Yea so considering how many people have reported no appetite control with retatrutide while cutting weight drastically by what mechanism would that happen? Personally only now joining the hype train ironically thanks to Chase Irons particularly interested by the gut health, blood sugar changes etc. but recomposition is welcome, people experienced with the 3 what would you say the main benefit is to retatrutide?

 

[DugPrime]

Yea so considering how many people have reported no appetite control with retatrutide while cutting weight drastically by what mechanism would that happen? Personally only now joining the hype train ironically thanks to Chase Irons particularly interested by the gut health, blood sugar changes etc. but recomposition is welcome, people experienced with the 3 what would you say the main benefit is to retatrutide?

It was making me hypoglycemic and lethargic, and overall, I didn’t find it helpful for cutting since it didn’t help with appetite. Now on tirz, my morning blood glucose is at 60-70. I feel much better mentally because my cut feels more like a bulk (forcing myself to eat), but I’m still as lethargic as I was on reta.

 

[Juggy3838]

It was making me hypoglycemic and lethargic, and overall, I didn’t find it helpful for cutting since it didn’t help with appetite. Now on tirz, my morning blood glucose is at 60-70. I feel much better mentally because my cut feels more like a bulk (forcing myself to eat), but I’m still as lethargic as I was on reta.

Retatrutide definitely makes you feel hypo. I’m only on 3.25mg and it makes me feel bad.

Felt the best on tirz. I wanted to try reta for liver health as I am a recovered alcoholic and wanted to cut down hard and use the glucagon agonism to rid any fatty liver left over.

Tirz doesn’t do much for hunger until you get up to 5+mg (for me). Also the anti-inflammatory effects of tirz are better. I lost a bit of lean tissue with reta. (Dieting on true HRT)

If I were a generally healthy bodybuilder….id do this…..

Start with Dash of semaglutide for the hunger blunting…even .25mg might be enough, paired with 2.5mg Tirz for the GIP agonism which helps nausea, and somehow enhances the anti inflammatory effects. Some might need .5mg/5mg…but I went that high and 2400 calories was requiring whey and rice Chex shakes

And this will be more cost effective than straight tirz

 

[Ghoul]

Retatrutide definitely makes you feel hypo. I’m only on 3.25mg and it makes me feel bad.

Felt the best on tirz. I wanted to try reta for liver health as I am a recovered alcoholic and wanted to cut down hard and use the glucagon agonism to rid any fatty liver left over.

Tirz doesn’t do much for hunger until you get up to 5+mg (for me). Also the anti-inflammatory effects of tirz are better. I lost a bit of lean tissue with reta. (Dieting on true HRT)

If I were a generally healthy bodybuilder….id do this…..

Start with Dash of semaglutide for the hunger blunting…even .25mg might be enough, paired with 2.5mg Tirz for the GIP agonism which helps nausea, and somehow enhances the anti inflammatory effects. Some might need .5mg/5mg…but I went that high and 2400 calories was requiring whey and rice Chex shakes

And this will be more cost effective than straight tirz

Do you use multiple syringes for this mix?

 

[DugPrime]

Retatrutide definitely makes you feel hypo. I’m only on 3.25mg and it makes me feel bad.

Felt the best on tirz. I wanted to try reta for liver health as I am a recovered alcoholic and wanted to cut down hard and use the glucagon agonism to rid any fatty liver left over.

Tirz doesn’t do much for hunger until you get up to 5+mg (for me). Also the anti-inflammatory effects of tirz are better. I lost a bit of lean tissue with reta. (Dieting on true HRT)

If I were a generally healthy bodybuilder….id do this…..

Start with Dash of semaglutide for the hunger blunting…even .25mg might be enough, paired with 2.5mg Tirz for the GIP agonism which helps nausea, and somehow enhances the anti inflammatory effects. Some might need .5mg/5mg…but I went that high and 2400 calories was requiring whey and rice Chex shakes

And this will be more cost effective than straight tirz

It will be more cost effective than straight tirzepatide, but I am wondering if instead of stacking two GLP-1 together, it wouldn't even be more effective to stack one of them with cagrilintide.

 

[Letits now]

Retatrutide definitely makes you feel hypo. I’m only on 3.25mg and it makes me feel bad.

Felt the best on tirz. I wanted to try reta for liver health as I am a recovered alcoholic and wanted to cut down hard and use the glucagon agonism to rid any fatty liver left over.

Tirz doesn’t do much for hunger until you get up to 5+mg (for me). Also the anti-inflammatory effects of tirz are better. I lost a bit of lean tissue with reta. (Dieting on true HRT)

If I were a generally healthy bodybuilder….id do this…..

Start with Dash of semaglutide for the hunger blunting…even .25mg might be enough, paired with 2.5mg Tirz for the GIP agonism which helps nausea, and somehow enhances the anti inflammatory effects. Some might need .5mg/5mg…but I went that high and 2400 calories was requiring whey and rice Chex shakes

And this will be more cost effective than straight tirz

The anti-inflammatory effects are huge. The gut inflammation always comes back when tirz isn’t in my system.

 

[Grey Spartan]

Man am I going to have fun when my Oct 20 oils promo lands. I have Mast E 200, Primo 200 and Test C coming this week. But Test C went out of stock after I ordered but they took so long to ship it came back in stock and made it into the order. Hopefully it’s either properly marked or cap colors are similar to yours.

TAKE A VIDEO OF THE UNBOXING. If you are shorted they will not reimburse you with out it, if at all.

 

[Sampei]

The anti-inflammatory effects are huge. The gut inflammation always comes back when tirz isn’t in my system.

Reta should have the same effect

 

[BP_6]

The anti-inflammatory effects are huge. The gut inflammation always comes back when tirz isn’t in my system.

When you say gut inflammation, what issues exactly are you referring to?

 

[5thGen]

Tomorrow they will.

It’s Tuesday. By You now.. let’s the promo of all oil promos

 

[Letits now]

Reta should have the same

I have been avoiding Reta because of the potential impact but I have it so might as well pin it now.

 

[dontletheoldmanin]

I have been avoiding Reta because of the potential impact but I have it so might as well pin it now.

What impact are you referring too?

 

[Letits now]

When you say gut inflammation, what issues exactly are you referring to?

I have always carried the extra in the gut. Started tirz and got the result I wanted. Titrated down and kept the eating clean. It still came back. Started pinning again and it went away. Then started reading about anti-inflammatory benefits.
So the affect may be anecdotal but I assumed it is related to the tirz.
And it’s not just fat. It’s almost like there’s some swelling.

 

[dontletheoldmanin]

I have always carried the extra in the gut. Started tirz and got the result I wanted. Titrated down and kept the eating clean. It still came back. Started pinning again and it went away. Then started reading about anti-inflammatory benefits.
So the affect may be anecdotal but I assumed it is related to the tirz.
And it’s not just fat. It’s almost like there’s some swelling.

Liver?

 

[Letits now]

What impact are you referring too?

Heart rate increase

 

[DeeX]

Retatrutide definitely makes you feel hypo. I’m only on 3.25mg and it makes me feel bad.

Felt the best on tirz. I wanted to try reta for liver health as I am a recovered alcoholic and wanted to cut down hard and use the glucagon agonism to rid any fatty liver left over.

Tirz doesn’t do much for hunger until you get up to 5+mg (for me). Also the anti-inflammatory effects of tirz are better. I lost a bit of lean tissue with reta. (Dieting on true HRT)

If I were a generally healthy bodybuilder….id do this…..

Start with Dash of semaglutide for the hunger blunting…even .25mg might be enough, paired with 2.5mg Tirz for the GIP agonism which helps nausea, and somehow enhances the anti inflammatory effects. Some might need .5mg/5mg…but I went that high and 2400 calories was requiring whey and rice Chex shakes

And this will be more cost effective than straight tirz

Phase 3 trial dosage is 2,4,6,9,12.

 

[Letits now]

Liver?

I did have some fatty liver issues but I had attributed that to the phenibut I was taking for a while. Plus I was 50 pounds heavier.

 

[BamaCrazy]

Heart rate increase

My resting HR went from 57 to 64 on Reta. Even higher would be a safe number.

 

[BP_6]

I have always carried the extra in the gut. Started tirz and got the result I wanted. Titrated down and kept the eating clean. It still came back. Started pinning again and it went away. Then started reading about anti-inflammatory benefits.
So the affect may be anecdotal but I assumed it is related to the tirz.
And it’s not just fat. It’s almost like there’s some swelling.

Thanks for the explanation. I asked because I on occasion have the same issue and it was even verified with a CAT scan as minor non specific inflammation. Which is funny because you read gut swelling can be a side effect of tirz so who knows. I might give it a try just to see.

 

[DeeX]

Yea so considering how many people have reported no appetite control with retatrutide while cutting weight drastically by what mechanism would that happen? Personally only now joining the hype train ironically thanks to Chase Irons particularly interested by the gut health, blood sugar changes etc. but recomposition is welcome, people experienced with the 3 what would you say the main benefit is to retatrutide?

I've been on 12 for a couple months now.

Took about 6 weeks to kick in...and when it does, it kicks in hard. I haven't been hungry on Reta since second week of 4 mg.

I wear a CGM now bc I went hypoglycemic when on Ozempic originally earlier this year (<30 glucose).

Context for rest of post: 1200 calories per day max, high protein low carb diet, supplementing with multivitamins, blood tests every few weeks to confirm everything is going perfectly.

Semaglutide experience: okay, hunger would come back end of every week, insane constipation + burping + acid reflux. HRV absolutely tanked, but stayed on it until hitting 1.7. Lost ~1/ lbs per week. Fatigued like crazy.

Tirzepatide: great, burping continued, but other side effects were mildly existent...laxatives + electrolytes made everything better. Titrated up to 10 mg, was losing 1.5 lbs/week.

Retatrutide: excellent, all side effects have gone away aside from burping. I do wake up middle of the night needing to chug water and am needing to drink electrolytes multiple times per day. On 12 mg dose, losing ~3.5 lbs/week. I am 20 lbs from my goal weight right now and normal weight range, losing weight hasn't slowed though.

Fatigued lasted a couple weeks on Reta, until I started to eat way more protein.