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I'm not going to open America, but it's no secret that pharma or AAS is one of the most effective means for gaining absolutely all conditions in sports. If you need mass, you're welcome. You need strength - even more so. There's no need to be sly, women today are using steroids left and right. Whether it's good or bad is up to each individual. Today we have a given.

The worst thing is that most people don't even know what will happen after using them.
However, many do not know even half of the side effects and most importantly how to deal with them. Now I will not talk about the side effects, we can devote a separate material to this. However, it is worth remembering that if somewhere there is a huge +, then somewhere it can get similar -. For in nature everything tends to balance.


If we are talking about the benefits of pharma, they can boost many aspects in the body that will give cool bonuses. These factors lead muscle tissue to an increase in hypertrophy, why, accordingly, many and chase (i.e., its increase). The most interesting thing is that in the past the priority was the strength and used danyye types of substances to increase it. Today the priority for many is appearance. So we will see a clash of the two camps in this area. The word anabolic comes from the Greek word for increase. But there is a full abbreviation androgenic anabolic. Androgen in turn means how - to make a man. This immediately brings to mind: but if a girl takes such drugs, what does she become
?)))



Unfortunately, most people today use such drugs for the purpose of attracting attention. The motivation to compete with the opposite sex is for many a fundamental factor. But this type of drugs was originally created for a different purpose.



Initially, I wanted to compile a chronology of how pharmacology was introduced into sports. But I encountered different sources and different opinions when writing it. Therefore, when reading this material, I try to proceed from a personal and subjective opinion. Here we go...



The history of steroids goes back so far and deep that many people simply cannot believe it. This can be seen about the research of any herbs and recipes of Granny Agafia in the past. The modern history of anabolic steroids is quite accurately indicated by the time the use of these substances began, which is the beginning of the 20th century.



There is information that pharmacology began to be used after the 50s of the 20th century. But I will talk about this a little further. However, in my personal opinion, certain substances affecting the increase of certain conditions affecting skills began to be used at the first Olympic Games. There is information that the first Olympic athletes, those whom we have the right to call the fathers of sport, consumed animal testicles before competitions; sometimes even for a long period of time, as part of their preparation for important competitions. There was hardly any awareness at the time: What? Where? Why? However, it's hard not to wonder who came up with these manipulations? Who in the rim of the topic, recall the stories about Uzbek ecdysterone and its comparison to a couple of wheels of methane. Or the emergence of D-aspartic acid on the sports nutrition market and the post-it analysis at the start. We can make a conclusion: for the sake of superiority over competitors, many people are willing to go to great lengths and even too great lengths.

Every mincemeat aficionado, seller of these substances and performing athletes can say thank you to Arnold Adolph Berthold. It was he who became one of the fathers of modern endocrinology. He was a native of Germany. He began to conduct the first and very serious experiments in the field of sex hormones. From about 1846 to 1849, he began to remove the testicles from young roosters (we are talking about animals, not mens physis). Thereby preventing them from developing as full-fledged males. This led him to a profound understanding of testicular function. I think at that point he realized-all the power is in the balls, but which are between the legs. Maybe that's why most athletes have a symbolic meal of eggs for tomorrow.) And that's what makes a man a man, not dangling them between his legs for beauty. The German was so keen on experiments that he even started transplanting testicles into the abdominal cavity. However, other conclusions were drawn there. Of course someone might say: But he did not shed any light on steroids, what does that have to do with it? However, these were the first steps toward exploring this topic.


Chemist Beginning. 1931. Guess where? Of course in Germany))) I'm honestly shocked at what they have in their heads and what they are capable of in a perverse way. The German chemist Adolf Boutenandt started a new movement. By this time, the importance as well as the significance of sex hormones was known. But it was Butenandt who became the father of steroids. He chemically filtered over 10,000 liters of urine (different sources give different numbers). This was a groundbreaking achievement, and also the beginning of a major breakthrough. And also thanks to it, we can see such competitions as Mr. Olympia. Through this filtration, he isolated a substance like Androstenone. The scientific community was not long in waiting, and already in a few years, someone's muscle structure was able to feel the full effect of these drugs.

After another German chemist, Leopold Ruzicka, developed a way to synthesize hormones. This process made it possible to start using it in humans. At this point, chemists were unstoppable, like a bikinist not to use oxandrolone. And in 1935, Ruzicka and Butenandt created the first batch of true synthetic testosterone. There's no doubt about it, this was the moment when the era of anabolic-androgenic substances was ushered in. The discovery was so cool and amazing that both scientists were awarded the Nobel Prize in Chemistry in 1939.

However, there is some information on the net. In the late 30s, an analogue of testosterone propionate was already introduced to man. In the 40s, this type of steroid was used in the Soviet Union. And there is information, in the 40's, the Olympic team of the Soviet Union was practically invincible. True, this lasted until the advent of "Daddy's Bread." John Ziegler, a doctor on the U.S. Olympic team created methane. Ciba Pharmaceuticals was the first pharmaceutical company to officially market this steroid. However, the Food and Drug Administration did not approve the product/Food and Drug Administration. Ciba did not stop and began to improve and synthesize new steroids.


However, the creator of steroids could also be a Russian. Igor Vladimirovich Torgov. He was born in Kazan in 1912. In 1937 he graduated from the Chemical Engineering Institute. After that he gets to the academy for the study of acetylene. However, there is a big, BUT. Acetylene is a compound of polycyclic ketones. And these substances are relatives of steroids. In the late 50's he is hired as head of the chemistry laboratory at the academy institute Shemyakin M.M. It was then that he could win the race to synthesize steroids. That's when the Torgov reaction, the complete synthesis of "diketone VI", was created. Afterwards, some Germans took this reaction as the basis and by modifying it, began to produce different kinds of steroid substances. For those in the tank, here is an example: 19-norsteroids have anabolic and gestagenic activity, and 19-nortestosterone and its esters are used in medicine as active anabolics. They increase protein synthesis in the body, but unlike androgens, they do not affect women as much.


I tried to surf various information on the creation of AAS and found the approximate truth. Medical use began as early as the 19th century. In the early 1930's Adolf Büttenandt was able to isolate 15 mg of the substance in the form of androstenone. Most interestingly, he got the whole thing from 10,000 liters of urine, in zeros I think I'm not mistaken. However, before him, in 1846, a certain Berthold, was interested in the workings of the glands that secrete sex hormones. He removed the testicles of roosters (I am not referring now to people of unusual appearance and behavior, but to menstruating mens-physicians). After that, the birds lost certain traits that made them males, and most importantly, their sexual function. But the dates after 1930 became primary for the creation of steroids.


The history of steroids in bodybuilding
Periodically on various bodybuilding forums on the Internet someone makes completely unfounded claims about steroid use, when it started and who used them in the "old days". When I see ignorance masquerading as fact, I almost always feel compelled to join the discussion and refute some of the frequently made outrageous claims. I am going to summarize what is known about the history of anabolic steroid use in sports so that I can direct people to this article instead of repeating it over and over again.

All reliable sources - publications by Terry Todd, John Fair, Randy Roach, Bill Starr, etc., as well as interviews and letters from John Ziegler, John Grimmack, Bill March, etc. - indicate that experiments with testosterone for sports purposes began in the U.S. sometime in late 1954 or 1955. These "trials," however, were short-lived, as the results were disappointing, and the use of testosterone was considered ineffective and carried the risk of harmful side effects. A statistical analysis of Olympic-style weightlifting performances published in the International Journal of Sports History showed that Soviet athletes probably first used testosterone sometime between 1952 and 1956.

Dr. John Ziegler, physician for the U.S. Olympic weightlifting team (i.e., the York team), described in an interview information about Soviet use of testosterone injections at the 1954 World Weightlifting Championships in Vienna, Austria, in October of that year. Some time after returning home, Ziegler convinced York's affiliated lifters John Grimek, Jim Park, and Yaz Cusahara to become test subjects and receive testosterone injections (by then it was known that oral testosterone was clinically ineffective). According to Grimek, the results were disappointing. In a private letter at the time, Grimek said he saw nothing in the way of success and stopping the injections because he felt he was actually regressing. Jim Pak received only one injection, which he claimed did nothing for him physically, but excited him greatly. It is unclear what happened to Cusahara, but, in any case, he was not positive enough to warrant continued use, and further experiments were discontinued. In light of the terrible side effects Ziegler heard about and saw the suffering of Soviet users, as well as the lack of meaningful results in his own test subjects, the York (USA) weightlifting team made no further attempts to experiment with testosterone during the 1950s. .

Ziegler's involvement with steroids wasn't the end of it, however. Ziegler began working with CIBA Pharmaceuticals in 1955 to develop a testosterone derivative that would have the anabolic properties of testosterone without unwanted side effects. Preliminary results began to come in by 1956, and in 1958 Dianabol was released to the U.S. market as a prescription drug for use in exhaustion. However, CIBA's competitor, Searle, beat them to the market and in 1956 introduced Nilevar, the first synthetic anabolic/androgenic steroid (used to treat polio), to the prescription drug market.

In late 1959 (some claim as early as 1958, some even as late as 1960) Ziegler decided to try out the new Dianabol on some York athletes who were not winning medals, and enlisted Grimek to convince several athletes to start using it under his (Ziegler's) ) Oversight. Lower-level or non-competitive athletes were chosen for initial testing so as not to jeopardize the possibility of medal contenders in the upcoming 1960 Olympics (at the time, Dianabol was a relatively untested drug, and York's chief Bob Hoffman reportedly had a fear of trying it on his top lifters). Bill March, Tony Garcy, John Grimek, Ziegler himself, and later Lou Rieke were the first guinea pigs, and this time



the results were much more promising.

After that, the use of Dianabol quickly spread to the entire York weightlifting team. Now promising York lifters and strength and health magazine writers such as Bill Starr and Tommy Suggs began to unlock the secret to the bodybuilding community, and by the early to mid-1960s almost all competitive high-level bodybuilders were taking steroids a few weeks before competition. This pre-competitive cycling scheme developed by bodybuilders was based on the practice of weightlifters to increase their steroid use in the weeks before weight lifting competitions - the logic was that just as bodybuilders wanted to be at their best (strongest) strength on competition day, bodybuilders wanted to peak on competition day. Steroid use didn't last long in the off-season either,

The man who would later become the first Mr. Olympia, Larry Scott, gained 8 pounds of muscle in the two months between the 1960 Mr. Los Angeles (in which he placed third) and the 1960 Mr. California (which he won). (beating the two men who had stood above him in Mr. Los Angeles two months earlier). A year earlier he had won the Mr. Idaho, weighing only 152 pounds. Larry believes that Reo Blair and his protein powder contributed to his sudden improvement. However, given Larry's dramatic gains from that point on and reports that Blair had possessed Nilevar several years earlier before he even moved to California, it is likely that this time in 1960 Larry first used steroids (which he admits to. but, to my knowledge, did not provide a date).

However, the early 1960s did not mark the true origin of regular steroid use by bodybuilders. In an early edition of his book, Getting Stronger, Bill Pearl recounted meeting Arthur Jones (founder of the Nautilus line of training equipment and father of the "HIT" training style) in 1958 and learning Nilevar from him. After a little additional research, Pearl began a twelve-week course of steroids and gained 25 pounds. Around the same time, Irwin Johnson (aka Reo H. Blair - the "father" of the first protein powders) is said to have had Nilevar Sirl in his possession, although it is not suggested that he was widely distributing it to bodybuilders. at the time.

So, what can we learn from all this? First of all, no bodybuilder or lifter used synthetic steroids before 1956-they didn't exist. Most likely by 1958, only the highest level bodybuilders from the West Coast knew about them. From there, it seems that knowledge of Nilevar and Dianabol for building muscle mass and strength was kept secret until the early 1960s. Eventually
, Hoffman didn't want outside athletes to know his athletes' secrets, and he used their sudden gains with Dianabol to promote his line of supplements and isometric training courses and racks. Bill Starr wrote that until he became a national caliber athlete at York in the early 1960s, he had never heard of steroids. Reg Park (Mr. Universe 1951, 1958, 1965) said he first heard about them in connection with rumors of East German and Soviet athletes during the 1960 Olympics, although he later heard of "steroids" being used by British prisoners of war from Singapore during World War II when they were treated back. health in Australian hospitals. Chet Yorton (Mr. America, 1966, Mr. Universe, 1966, 1975) said that he first heard about steroids (Nilevar) in 1964 and decided not to risk using them - Yorton became one of the most active fighters for the sport. steroid use and founder of the first drug-tested natural bodybuilding federation. Between 1960 and 1964, the condition of national and world-class bodybuilders seems to have improved considerably. used on British prisoners of war from Singapore during World War II, when their



treated in Australian hospitals. Chet Yorton (Mr. America, 1966, Mr. Universe, 1966, 1975) said that he first heard about steroids (Nilevar) in 1964 and decided not to risk using them - Yorton became one of the most active fighters for the sport. steroid use and founder of the first drug-tested natural bodybuilding federation. Between 1960 and 1964, the condition of national and world-class bodybuilders seems to have improved considerably. used on British prisoners of war from Singapore during World War II, when they were treated in Australian hospitals. Chet Yorton (Mr. America, 1966, Mr. Universe, 1966, 1975) said that he first heard about steroids (Nilevar) in 1964 and decided not to risk using them - Yorton became one of the most active fighters for the sport. steroid use and founder of the first drug-tested natural bodybuilding federation. Between 1960 and 1964, the condition of national and world-class bodybuilders seems to have improved considerably. and decided not to risk using them - Yorton became one of the most active fighters for steroid use and founder of the first drug-tested bodybuilding federation. Between 1960 and 1964, the condition of national and world-class bodybuilders seems to have improved considerably. and decided not to risk using them - Yorton became one of the most active fighters for steroid use in the sport and the founder of the first drug-tested natural bodybuilding federation. Between 1960 and 1964, the condition of national and world-class bodybuilders seems to have improved dramatically.

As for testosterone itself, Paul de Cruyff's 1945 book, The Male Hormone, is often called "proof" that bodybuilders knew and used testosterone in the 1940s. But even though testosterone was identified by researchers and isolated in the laboratory as early as the 1930s, it did not receive FDA approval as a prescription drug until 1950, and consequently injectable testosterone was only produced sporadically and in small batches for research purposes. , prior to that time. De Cruyff himself made no clear connection between the use of testosterone and its possible applications in sports, although he briefly raised the question of whether it could trump the effects of large doses of vitamins in baseball players--beyond that single suggestion,

It has been said that John Grimek, reading such publications as de Kruif, was interested in testosterone in the 1940s. But he had nothing but a possible hunch that it could be used for athletic purposes, and there would be no source or opportunity to experiment with it. In fact, in the late 1940s there were two companies in California advertising "real testosterone" pills through the mail, but in early to mid-1951 they were ordered to cease doing so when regulations to control the distribution of controlled substances were tightened. . However, it was well known to researchers at the time that the liver effectively eliminated almost all the testosterone taken orally in seconds, even at very high doses (clearance rate of 24.5 mg/min/kg). so these pills would have had no effect even if they had actually contained crystal testosterone. The low bioavailability of oral testosterone is why injectables were used in early studies and why synthetic steroids were eventually developed.

It wasn't until 1954/1955 with Ziegler that Grimek wrote about his first testosterone injections. It goes without saying that even if Grimek didn't have access to bioavailable testosterone until 1954-55, he didn't know about it. And didn't know of any other top-level bodybuilders or lifters using it before that time-and as Strength and Health editor and deputy commander at York he certainly was in a position to know-then it is very unlikely that anyone in the West was effectively using testosterone for athletic purposes before late 1954/1955.



Given that these early experiments were unsuccessful and short-lived (probably because they knew little about dosing to increase strength and muscle mass), it is most likely that the first Western bodybuilders started using steroids not with testosterone, but with Nilevar, sometime after 1956 1958. From there

For a Western bodybuilder or lifter to start using testosterone before late 1954/1955, he had to know more about the biochemistry of testosterone and its potential athletic effects than any Western sports doctor, and have access to what was then a relatively rarely used. prescription drug. He also had to know more about how to dose it effectively than John Ziegler, who went on to co-develop Dianabol just a few years later. No one in the West can say exactly when the Soviets began using testosterone, but a likely date is sometime before October 1954 and possibly as early as 1952.

As mentioned, injectable testosterone was first approved for prescription as a treatment for cancer, debility, and burns in the United States in 1950. Prior to that, it was only available for research purposes, with stricter FDA regulations in the early 1950s. Two California companies advertised "real testosterone pills" in national newspapers from 1946 to 1951, but the actual ingredients of these pills were not controlled, could not be tested, and because of the elimination rate, oral testosterone would have no value anyway. For a bodybuilder to use testosterone effectively before 1950, he not only had to know more about its biochemistry, dosage, and possible athletic uses than anyone else in the world (including research scientists working with it), but also had access to what was then an experimental drug, isolated in limited quantities for controlled research purposes and not produced in large quantities for public consumption or the prescription market. Advertisements for "snake oil" testosterone pills, even if they contained what was advertised (which in itself was vague), would not have had a significant effect on blood testosterone levels because of the high elimination rate of testosterone by the liver and cannot be considered a reliable source.

For these reasons, it is almost certain that Steve Reeves, Clancy Ross, John Grimmack, Jack Dellinger, Reg Park, John Farbotnik, George Eiferman, etc. D. - all of whom won major physique titles before the Soviets began using testosterone and before synthetic steroids. were introduced in 1956 - did not use bioavailable testosterone or synthetic steroids during their victories in Mr. America, Mr. USA and Mr. Universe. Moreover, it is unlikely that any of the major titleholders took steroids before 1957-58 (Pearl had won the Mr. USA and Mr. Universe titles in 1956 before he knew about Nilevar). The careers of some athletes of that era, such as Reg Park, are really tied to the introduction of steroids in bodybuilding. In Park's case, he weighed 226 pounds when he won the Mr. Britain title in 1949, 214 pounds when he won the Mr. Universe title in 1951, 215 pounds when he won a second time in 1958, and 216 pounds when he placed 3rd in 1971 (at age 43 -- he was back in 1973, placing 2nd). If Park really jumped on the steroid bandwagon when he learned about them in 1960, they grew him one pound of muscle in 11 years.
 
Why is this last batch of sustanon giving an ugly seed? I had 3 injections with lumps and pain after a few days. Injections of 1 ml intramuscularly
 
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¿Es normal que con oxandrolona 40mg al día me duelan las articulaciones?

Is it normal that with oxandrolone 40mg per day the joints hurt?
 
By now I have had between my hand several products from different vendors, both pharma and ugl. I would like to compliment you on the quality of your packaging, consistent quality, dosing and also the speed of your shipping.

From my side you are as close to pharma as an ugl can be.
 
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