SymBiotics (U.S. domestic)

Same here man, I really only have time right before bed to do it during the week. A lot of times I'll crash and forget. Fuck by then I cant think about anything other then my head hitting the pillow.

I know how it feels man, haha. I would pin before bed, but I've discovered if I pin Tren before bed it completely fucks my sleep up. Therefore, I just try and pin everything in the morning no matter what I'm running at the time.
 
@SymBiotics Although this has been covered sporadically across different sources/forums I was mainly interested in your opinion and knowledge/expertise on the matter.
Oral suspensions I have heard mainly from sources are much easier to dose in accuracy in comparison to tabs/caps.
Three questions:
-Do orals really hold well or have some risk for the compounds to fall out of the suspension itself?

-Does temperature affect its bioavailability if outside the temperature range of holding?

-Although it is always recommended that you shake it vigorously before oral administration,
Is there a chance of the desired dose to not contain the correct amount of mgs within the dose itself due to not shaking it to a specific level? Sometimes settling could risk this?
 
@SymBiotics Although this has been covered sporadically across different sources/forums I was mainly interested in your opinion and knowledge/expertise on the matter.
Oral suspensions I have heard mainly from sources are much easier to dose in accuracy in comparison to tabs/caps.
Three questions:
-Do orals really hold well or have some risk for the compounds to fall out of the suspension itself?

-Does temperature affect its bioavailability if outside the temperature range of holding?

-Although it is always recommended that you shake it vigorously before oral administration,
Is there a chance of the desired dose to not contain the correct amount of mgs within the dose itself due to not shaking it to a specific level? Sometimes settling could risk this?

The reasons I prefer suspension or solution over capsules are multiple:
  • Homogenization is much more readily achieved.
  • Alterations in homogeneity are often visible with liquids; in contrast to active ingredients and capsule fillers which are often the same color
  • Incremental dosing with accuracy is possible with liquid medications
  • Medications are more rapidly and readily absorbed in liquid form
  • The little bottles and syringe adapters are neat and unique to my products in the underground :D
Like most liquids, the suspension vehicle's viscosity will be altered by temperature. The vehicle is formulated to suspend particles at room temperature. I feel certain that some of the suspension property would change with decreased viscosity that commonly is associated with heating liquids.
Within reason, this suspension vehicle will return to its normal state after reaching room temperature following a period of higher temperature.
Now, this does not apply to excessive temperatures, such as boiling or near boiling. I'm sure that would alter the vehicle permanently; so I definitely would not recommend that. I can't fathom a reason for such an action either.
One person asked me about the stability of his suspension that was in the mailbox for a few hours during the day. I believe it will return to its original state upon reaching room temperature following a period of mild temperature increase like that. It would be safe to use.

Bioavailability is not affected by the suspension vehicle. For bioavailability of a medication to be altered, processes which change the absorption or chemical properties of the medication must be applied; or the route of administration must be changed.
These suspensions are identical to the vehicle that pediatric acetaminophen, and many other drugs are compounded in.
If you have young children, chances are you probably have filled a prescription for them that was in liquid form. Many medications are not commercially offered in suspension; so they are created by a compounding pharmacist. The compounding pharmacist will take the medication, often in tablet form; and pulverize it in a mortar and pestle. Then the powdered tablets are homogenized into suspension with the very same vehicle that I am using for my products. In fact, I pick it up from a place that does exactly that.

Yes, you have to shake them. There is nothing available that will defy the law of gravity. If left alone long enough, any medication will settle out of suspension. Even Children's Tylenol must be shaken prior to dosing. The R&D behind the suspension vehicles used today in compounding pharmacy has proven that shaking the container, after a period of being motionless, will redistribute the medication to nearly the same degree of homogeneity as when it was first compounded.

I hope that answers your questions.
 
@SymBiotics, so after the initial 6 testosterone tests, you will not offer any future credit for test bloodwork? Not trying to criticize you but many other sources do offer something. It encourages people gets bloodwork and ensures you're still putting out a good product.
How to answer this?????
I don't know just yet.
Here are my thoughts:
I spent thousands of dollars to have the raw materials tested by the analytical service that seemed to be the most popular at the time; and they tested well.
Finished products have been sent in for testing; and they tested well. The testers were compensated at a rate greater than their cost for products, shipping, and testing.
I am offering compensation for serum analysis; which is highly variable among different genetics.
There comes a point at which one would lose interest in financing repetitious testing on the same substance.
Take my testosterone enanthate 300mg/ml for example:
The raw material tested very pure. The finished product tested at accurate dosage. I will be compensating for the first serum value posted for that compound. There is such a thing as testing something into monotony.
So, if it starts good, is good in the middle, and ends good; where is the benefit to anyone to keep testing the exact same thing? There should be quite some time before my testosterones are replaced by a new batch; but I will definitely consider repeat serum analysis compensation when that time comes.

Regarding what "ensures you're still putting out a good product":
I am the singular force that can affect the quality of my product. 100 people can test what I make; and it is still up to me to do it right.
 
I hope everyone has a great weekend. I plan to be unreachable tomorrow afternoon while watching a football game; but I will return here later at night.
Goodnight to you all.
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The reasons I prefer suspension or solution over capsules are multiple:
  • Homogenization is much more readily achieved.
  • Alterations in homogeneity are often visible with liquids; in contrast to active ingredients and capsule fillers which are often the same color
  • Incremental dosing with accuracy is possible with liquid medications
  • Medications are more rapidly and readily absorbed in liquid form
  • The little bottles and syringe adapters are neat and unique to my products in the underground :D
Like most liquids, the suspension vehicle's viscosity will be altered by temperature. The vehicle is formulated to suspend particles at room temperature. I feel certain that some of the suspension property would change with decreased viscosity that commonly is associated with heating liquids.
Within reason, this suspension vehicle will return to its normal state after reaching room temperature following a period of higher temperature.
Now, this does not apply to excessive temperatures, such as boiling or near boiling. I'm sure that would alter the vehicle permanently; so I definitely would not recommend that. I can't fathom a reason for such an action either.
One person asked me about the stability of his suspension that was in the mailbox for a few hours during the day. I believe it will return to its original state upon reaching room temperature following a period of mild temperature increase like that. It would be safe to use.

Bioavailability is not affected by the suspension vehicle. For bioavailability of a medication to be altered, processes which change the absorption or chemical properties of the medication must be applied; or the route of administration must be changed.
These suspensions are identical to the vehicle that pediatric acetaminophen, and many other drugs are compounded in.
If you have young children, chances are you probably have filled a prescription for them that was in liquid form. Many medications are not commercially offered in suspension; so they are created by a compounding pharmacist. The compounding pharmacist will take the medication, often in tablet form; and pulverize it in a mortar and pestle. Then the powdered tablets are homogenized into suspension with the very same vehicle that I am using for my products. In fact, I pick it up from a place that does exactly that.

Yes, you have to shake them. There is nothing available that will defy the law of gravity. If left alone long enough, any medication will settle out of suspension. Even Children's Tylenol must be shaken prior to dosing. The R&D behind the suspension vehicles used today in compounding pharmacy has proven that shaking the container, after a period of being motionless, will redistribute the medication to nearly the same degree of homogeneity as when it was first compounded.

I hope that answers your questions.

Geez dad, I just asked for help with my algebra
 
How to answer this?????
I don't know just yet.
Here are my thoughts:
I spent thousands of dollars to have the raw materials tested by the analytical service that seemed to be the most popular at the time; and they tested well.
Finished products have been sent in for testing; and they tested well. The testers were compensated at a rate greater than their cost for products, shipping, and testing.
I am offering compensation for serum analysis; which is highly variable among different genetics.
There comes a point at which one would lose interest in financing repetitious testing on the same substance.
Take my testosterone enanthate 300mg/ml for example:
The raw material tested very pure. The finished product tested at accurate dosage. I will be compensating for the first serum value posted for that compound. There is such a thing as testing something into monotony.
So, if it starts good, is good in the middle, and ends good; where is the benefit to anyone to keep testing the exact same thing? There should be quite some time before my testosterones are replaced by a new batch; but I will definitely consider repeat serum analysis compensation when that time comes.

Regarding what "ensures you're still putting out a good product":
I am the singular force that can affect the quality of my product. 100 people can test what I make; and it is still up to me to do it right.
So will you offer compensation for each new batch that gets tested by the public?
 
Low key I think SymBiotics agree’s with me that bloodwork is bullshit (I’m borderline joking), but there are just too many variables to consider. I looked through TGI’s bloods last night randomly. One guy had 1500ng on 500mgs, another had 3220 on 500mg.... Fuck bloodwork I think compensation should be given for ALL WM mass spec reports, and that should remain permanent. If you guys care about what’s in your vials then you will send them off for testing. Save the bloodwork for your own personal health/cycle records.
 
@SymBiotics Am I missing it or do the 10ml Vials not have batch numbers on them? I noted a number 1 over a letter “S” sticker under the vials themselves but was unsure if this is related to anything to do with the Batch#
Same thing for your oral suspensions, no batch # other than the number 1 over the S located on the back of the bottle.
Although your raws have been tested as well as members sending in completed compounds with all positive results. I would of assumed there would be some degree of record keeping with Batch#’s between the supplier and consumer to reference to, if the instance would ever to arrive with questioning of a specific compound.
Please advise
 
@SymBiotics Am I missing it or do the 10ml Vials not have batch numbers on them? I noted a number 1 over a letter “S” sticker under the vials themselves but was unsure if this is related to anything to do with the Batch#
Same thing for your oral suspensions, no batch # other than the number 1 over the S located on the back of the bottle.
Although your raws have been tested as well as members sending in completed compounds with all positive results. I would of assumed there would be some degree of record keeping with Batch#’s between the supplier and consumer to reference to, if the instance would ever to arrive with questioning of a specific compound.
Please advise

Never mind, I forgot how amazing the search function in Meso is to just find Information. On page 13 post#247 you said:
“Batch numbers are already on each product container. Currently everything is marked batch 1; and this will correspond to the first batch of each compound. I apologize for not including an image of them in the introduction.”

So I guess I answered my own question, but I’ll leave both my entries intact Incase anyone else was wondering.
Thanks @SymBiotics
 
Low key I think SymBiotics agree’s with me that bloodwork is bullshit (I’m borderline joking), but there are just too many variables to consider. I looked through TGI’s bloods last night randomly. One guy had 1500ng on 500mgs, another had 3220 on 500mg.... Fuck bloodwork I think compensation should be given for ALL WM mass spec reports, and that should remain permanent. If you guys care about what’s in your vials then you will send them off for testing. Save the bloodwork for your own personal health/cycle records.

Agreed. Blood tests were the “go to” when product testing wasn’t available. It’s the 2nd best option and probably only a little bit better than stupid RoidTest.

@SymBiotics can you consider offering your product testing credit to anyone that makes the effort to send product off to be tested? Or at least for the first to submit new batch of each product?

The more testing you have the better and honestly, members are lazy (myself included) so you’re not going to have a run on testing credit.
 
Agreed. Blood tests were the “go to” when product testing wasn’t available. It’s the 2nd best option and probably only a little bit better than stupid RoidTest.

@SymBiotics can you consider offering your product testing credit to anyone that makes the effort to send product off to be tested? Or at least for the first to submit new batch of each product?

The more testing you have the better and honestly, members are lazy (myself included) so you’re not going to have a run on testing credit.

I agree with you and @Masterofron
 
@SymBiotics I have to be honest I am a bit dissappointed with the current stance on blood work compensation. As @Tiredandhot said I feel that it encourages people to get more blood work, which in return shows people that the quailty behind your work still is top notch. However, compensation for testing the product could be a decent solution.
 
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I see both sides with blood work compensation. The fact is most of us will get blood work done anyways so on one hand that’s for me but also on the other hand I like being transparent and helping the community. I legit out of the dozen or so blood work I have done I have only taken credit once. I’ll be honest it was awesome because I do mid cycle blood work anyways and to get 150 in credit was a bonus.

To sum up my opinion... I have none
 
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