MESO-Rx Exclusive The Most Effective Growth Hormone Protocol for Fat Loss

[ChestRockwell]

How administration and doses would change during bulking? Me and my wife are just starting offseason.bulk and wanted to optimize use of hgh.

Could we just use it for lypolitic effect to avoid/reduce an increase of bf during bulking following the guideline above?

No, because if you've read this article you realize how potentially important abstaining from eating (fasting) is to the maximal lipolytic potential of GH. This is not conducive to an effective lean mass gaining phase!

If you can exercise just a bit more patience, @Millard Baker is currently performing final passes on part two and we'll hopefully have it posted very shortly!

 

[Sampei]

Well if you time.it right you can fast during the night and you can wake up at like 00 am inject and go back to sleep

That could work i guess.
I'll wait for part two

No, because if you've read this article you realize how potentially important abstaining from eating (fasting) is to the maximal lipolytic potential of GH. This is not conducive to an effective lean mass gaining phase!

If you can exercise just a bit more patience, @Millard Baker is currently performing final passes on part two and we'll hopefully have it posted very shortly!

 

[Deleted member 59947]

@kevinhy Yessir, you are spot on. The maximal rate of lipolysis is stimulated closer to 1IU, however I use 2IUs in my recommendation simply for convenience factor.

My assumption would be that it provides a bit of room for error and most folks would rather ensure maximal rate is achieved, even if slightly more GH is used than technically required. Furthermore, even 1IU of GH can cause lipolytic rates to exceed baseline for 4-8 hours and so most folks will really only have two realistic times during the day when fasting for this long is feasible.

Long story short, you are absolutely correct, but there is a method behind my recommendation madness...

Don’t we produce around 1.25iu a day naturally?
Why the need for that 1-2iu dose then if we are going to shut ourself down for 24h? All what’s going to be in our blood is 1-2iu, without out natural 1.25iu.

 

[DragoT]

Don’t we produce around 1.25iu a day naturally?

Yes, if the subject is healthy 25 years old, with healthy living style, going to bed at 10pm, avoiding carbs after 8pm, have 8-9 hours sleep... I can go on. And then... we age.

Look the average male population age 45+ - what do you see? Beer belly, man boobs, the whole nine yards. Why? Besides the typical American diet , GH production is nowhere near 1.25IU, declining testosterone production and explosion of aromatase receptors in the fatty tissue.

I maintain that there is no "magic" formula to calculate the "optimal" protocol. Instead, via blood testing, one should find the dose that produce sustained IGF-1 levels above the statistical median for the appropriate age group.

Seeking abnormally high IGF-1 levels for alleged muscle growth is whole other subject.

 

[ulfbehrt]

I'm mid 40's and my sweet spot is 5iu's of a good generic before bed. I've always done Mon-Fri with weekends off 5/2 method and it's worked like a charm in terms of fat loss and muscle tone.

 

[ChestRockwell]

Don’t we produce around 1.25iu a day naturally?
Why the need for that 1-2iu dose then if we are going to shut ourself down for 24h? All what’s going to be in our blood is 1-2iu, without out natural 1.25iu.

Great question, and I can see why this would be confusing at first glance.

It is true that males during puberty can produce upwards of 1-1.5IUs/day, we also must remember that levels of GH secretion decline by as much as 10-15% each decade after the age of 20.

In addition, comparing endogenous secretory pharmacokinetics to those with rHGH are an apple vs. orange scenario. Why rHGH is advantageous to lipolysis is due to its ability to maintain elevated levels of serum GH for many hours at a time. The entire time serum GH is elevated, FFA mobilization rates are increased, providing an environment ideal for fat loss.

 

[ChestRockwell]

I maintain that there is no "magic" formula to calculate the "optimal" protocol.

Except there is for lipolysis, and it is illustrated in the article

 

[Mr.Perfect]

I'm mid 40's and my sweet spot is 5iu's of a good generic before bed. I've always done Mon-Fri with weekends off 5/2 method and it's worked like a charm in terms of fat loss and muscle tone.

I'd like to know what generic gh in Canada you think is good?

 

[DragoT]

Why rHGH is advantageous to lipolysis is due to its ability to maintain elevated levels of serum GH for many hours at a time. The entire time serum GH is elevated, FFA mobilization rates are increased, providing an environment ideal for fat loss.

Amen, can't be explained better.

Still (I am stubborn elderly, you know) - my comment was more or less for us, generic users. I'd take your excellent article is sole based on studies done with Pharma grade rHGH where quality, purity and potency is (expected to be) the same at any given moment.

I typically order 4 months of supply at once. Last year I had a batch that produced 15.1 ng/mL Serum GH after 3 hours 10IU administration. I had to go with 4IU daily to maintain IGF-1 at ~250 ng/mL.

The next batch produced Serum of 23.6, IGF-1 went to 320 at 4IU, and so, I reduced to 3IU/daily.

Of course, it all depends of the personal goals, but yes, you are absolutely correct that Pharma grade 1.5-2.0IU would:

1. Suppress own production (in sustained way)
2. Elevate IGF-1 in sustained way where IGF-1 would be in the 2/3 high end of the reference range).

As I said, I all make sense now.

 

[ulfbehrt]

I'd like to know what generic gh in Canada you think is good?

I always use to order from Homer and it was always good.

 

[ChestRockwell]

Still (I am stubborn elderly, you know) - my comment was more or less for us, generic users. I'd take your excellent article is sole based on studies done with Pharma grade rHGH where quality, purity and potency is (expected to be) the same at any given moment.

Ah, gotcha. You are absolutely correct that my articles are working off the assumption one is using FDA grade rHGH. I do not recommend the use of off-label brands, in fact I touch on this subject in more depth in part two.

 

[Wunderpus]

Amen, can't be explained better.

Still (I am stubborn elderly, you know) - my comment was more or less for us, generic users. I'd take your excellent article is sole based on studies done with Pharma grade rHGH where quality, purity and potency is (expected to be) the same at any given moment.

I typically order 4 months of supply at once. Last year I had a batch that produced 15.1 ng/mL Serum GH after 3 hours 10IU administration. I had to go with 4IU daily to maintain IGF-1 at ~250 ng/mL.

The next batch produced Serum of 23.6, IGF-1 went to 320 at 4IU, and so, I reduced to 3IU/daily.

Of course, it all depends of the personal goals, but yes, you are absolutely correct that Pharma grade 1.5-2.0IU would:

1. Suppress own production (in sustained way)
2. Elevate IGF-1 in sustained way where IGF-1 would be in the 2/3 high end of the reference range).

As I said, I all make sense now.

Have you checked your blood glucose levels with IGF-1 at that level? I just started taking berberine, and I already feel much better and my pumps are INSANE in the gym. Seems like a LOT of type 2 diabetics are trending towards berberine usage over metformin. Just a thought, as it's almost always an issue with high GH usage.

 

[Roco Bama]

Have you checked your blood glucose levels with IGF-1 at that level? I just started taking berberine, and I already feel much better and my pumps are INSANE in the gym. Seems like a LOT of type 2 diabetics are trending towards berberine usage over metformin. Just a thought, as it's almost always an issue with high GH usage.

Have you tested your BG after administering HGH ? My BG tend to be 109-111 3-4 hours after meal and 15iu in one shot.

 

[Roco Bama]

When is the HGH protocol for muscular growth coming up Chestrockwell

 

[Wunderpus]

Have you tested your BG after administering HGH ? My BG tend to be 109-111 3-4 hours after meal and 15iu in one shot.

I haven't, but I am ordering a meter.... I want to start testing it ASAP

 

[ChestRockwell]

When is the HGH protocol for muscular growth coming up Chestrockwell

It has already been submitted to @Millard Baker and he's going through it now. It will be worth the wait though, I'm actually quite proud of this one!

 

[DragoT]

My BG was 101 mg/dL (65-99) three hours after 10IU (blood drawn after 10h fasting). But then again, I do not exceed 2-3IU/day and avoid fast acting carbs as plague. Last Coca Cola I've had (Hecho en Mexico, with real sugar) was somewhere around May 2016.

 

[Mr.Perfect]

I always use to order from Homer and it was always good.

Homer & TP are about the only good generic hgh you'll find in Canada, but guys have to import these in or pay an arm and a leg to domestic suppliers that take the risk importing greys and blacks. I hear good things about Jeotrop but would like to see hplc done on it from Jano.I know for a facvt neaouvotrope is fake and so is triton. Norvotrop and Primatropin is junk as well. You'll find the guys that say it is are reps or schills for the big 2 competitors newport & bodytech (both labs are nothing special imo). That's why this board is so great, no deletion of posts, and no rules saying you can't post results from HGH tests.

 

[Deleted member 59947]

Amen, can't be explained better.

Still (I am stubborn elderly, you know) - my comment was more or less for us, generic users. I'd take your excellent article is sole based on studies done with Pharma grade rHGH where quality, purity and potency is (expected to be) the same at any given moment.

I typically order 4 months of supply at once. Last year I had a batch that produced 15.1 ng/mL Serum GH after 3 hours 10IU administration. I had to go with 4IU daily to maintain IGF-1 at ~250 ng/mL.

The next batch produced Serum of 23.6, IGF-1 went to 320 at 4IU, and so, I reduced to 3IU/daily.

Of course, it all depends of the personal goals, but yes, you are absolutely correct that Pharma grade 1.5-2.0IU would:

1. Suppress own production (in sustained way)
2. Elevate IGF-1 in sustained way where IGF-1 would be in the 2/3 high end of the reference range).

As I said, I all make sense now.

The fact that you tested once at 15 and another time at 23 is more likely due to your own body HGH processing fluctuations than the quality fluctuations of the batches.

You can’t expect your body to process exogenous substances at the same speed or with the same efficacy when all other parameters aren’t stricly equal

 

[DragoT]

@Goingstronger I don't dispute your argument. However, when I test a batch (via serum), I also test IGF-1. The main difference is - serum shows the effect of 10IU (new batch) sub-q 3 hours after pin, whereas IGF-1 is to evaluate the result of 4 months continuous use of X IU's (previous batch).

I follow very strict pre-blood protocol (10 hours fasting, blood drawn 8:05 am - first customer when lab open) to avoid external factors. Even the same day of the week (in conjunction with my Test C shot) i.e. trying to approach the whole thing "scientifically"

It all comes down to personal goals. I said many times - my goal is to stay in upper 95% of the reference range of my age group.

On another note, here is my HT progress at 3.5 month mark.