Those suggestions make sense generally, but do you have any clinical experience or data to show that doing those things while taking supranormal doses of gear will lower CRP?
Is CRP a direct indication of some specific bodily pathology?
MESO-Rx
Anabolic Steroids
Uncle Chad’s Test 300 cycle
- Thread starter Uncle Chad
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Is CRP a direct indication of some specific bodily pathology?
Uncle Chad
New Member
ESR and CRP are the two values used to detect inflammation in the body. There are other inflammation markers that can be measured, but CRP is good for predicting cardiovascular risk and showing non-specific inflammation.
I cannot cite articles here, but a quick google search, ie "effect of sleep on CRP research" should point you in the right direction. There are not enough studies done on AAS users but the general consensus is that those things I mentioned decrease inflammation.
I'd suggest you follow a few pages on Instagram that like to cite research targeted towards bodybuilders: J3University, menno.henselmans and biolayne.
But I'll be totally honest with you: if you cycle without a coach, it's gonna be a rough road and you will make mistakes no matter how much you educate yourself. I value my coach for his personal experience with over 100 clients, not for his "book" knowledge.
Reducing inflammation as much as possible is always a good thing, but my point is that one should probably put more stock into markers directly indicative of clinical pathology. I imagine a big portion of people on high doses will have high ESR/CRP no matter what other measures they take. High doses increase inflammation and are in effect bad for ones health, but one has to decide if they’re willing to accept that risk and if they’re willing to abstain from blasting later on while they recover.
All in all, I think there are better markers of clinical issues than esr/crp if one doesn’t have any other chronic health issues before starting gear. The best marker of lipid buildup is ApoB rather than the standard American lipid panel.
Uncle Chad
New Member
i just read up on why ApoB is used, that’s a really good point you’re bringing.
do you know of any other inflammation markers that bodybuilders would benefit from using?
my coach recently told be that GGT is a more specific marker for liver injury, rather than AST and ALT.
I’ve known ggt to be better associated with gallbladder pathology.
Transaminases for liver. Alt>AST in fatty liver. AST>ALt in alcoholic liver disease. Platelets can be reviewed as an acute phase reactant. Ammonia with chronic disease.
D
Deleted member 59947
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Hi Chad,
Careful with the multivitamin as it countains B6 in the form of pyridoxine and not P5P, which could cause nerve damage if used long term
Uncle Chad
New Member
Columbia was really good, so much cheap food and fun tours. I did end up front loading my dosages for the week and felt absolutely fine. Me and my friend put in 3 workouts while being there and tried eating with high amounts of protein. (majority of their food is very fatty so you gotta ask for double chicken all the time)
Uncle Chad
New Member
oh yes sir, i don’t want that peripheral neuropathy coming for me.Hi Chad,
Careful with the multivitamin as it countains B6 in the form of pyridoxine and not P5P, which could cause nerve damage if used long term
Uncle Chad
New Member
One year progress since i hopped on gear and started working with my coach. 2 cycles done so far. +35 lbs of lean mass.
Lately i’ve been eating ~3400 calories a day and we’re going to do an aggressive cut with 1500 calories for 4-5 weeks.
Also switching to 150 mg Test only this period of 4-5 weeks. (hopefully i don’t lose too much lean mass since my nitrogen balance will take about 1 month to fall back into the natty range)
Lately i’ve been eating ~3400 calories a day and we’re going to do an aggressive cut with 1500 calories for 4-5 weeks.
Also switching to 150 mg Test only this period of 4-5 weeks. (hopefully i don’t lose too much lean mass since my nitrogen balance will take about 1 month to fall back into the natty range)
This is what progress thread are all about!
On the first page you mentioned you were concerned about your hair. I see you’ve run primo since. How’s the hair line holding up?
lukiss96
Well-known Member
Good progress, so first cycle was 300mg Test only and what was the second one?
Lmao we hopped on around the same time and your progress is low key having me regret that I came off for 3 months after my first cycle. When the next cycle started, just like the first one, took 5-7 additional weeks to really be “on”. Probably closer to 7 because I (somewhat stupidly) did 200 test 100 primo first 4 weeks to assess e2, primo tolerability, sides, etc and then went up to 250 test, then 300 test 150 primo 4 weeks after that. Was very wary of estrogen being too low or too high but in hindsight should’ve gone to 300/150 sooner. When I was in the 200/250 range with the 100 primo, I ate whatever I wanted like crazy and didn’t gain any body fat, but muscle gain was super slow. Gains truly picked up when I went to 300 test. Overall on this blast with primo I made more lean gains than my first test 350 cycle when my e2 was near 100 and I started tapering down 14 weeks in lol.
All that said, bloods normalized pretty well by me coming off (and now they’re worse so I’ll cruise soon). I’d check yours now that you’re likely nearing the end of your second blast?
All that said, bloods normalized pretty well by me coming off (and now they’re worse so I’ll cruise soon). I’d check yours now that you’re likely nearing the end of your second blast?
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