2,4-DiNitroPhenol [DNP]

Heretic

New Member
Credit to the gods that wrote this... :)

HOW TO NOT FUCK UP DNP:

Since some guys have been playing around and disrespecting DNP and then griping to the forums about the painful results, we need to make this VERY specific and VERY correct so that people won't keep jumping for DNP out of curiosity, or without the willpower they need to operate this respondibly. So here are my experienced guidelines to using it the RIGHT way.

FIRST GUIDLINE: Dosing. Use ONLY 200mg a day for the first four days. I don't care that you don't "feel" anything yet and you wanna bump it up. DNP accumulates in the body, and not "feeling" something means NOTHING. It's there, and it's working (the effect on metabolism begins within two hours of the first dose!). Four days will let you test your tolerance: do you have an allergy? Does it give you a rash? etc.
Only after those four days do you bump it up, by 200mg a day. The average dose is 400-600/day, and more than that gets a little severe. A full gram is the highest dose I've heard anyone use. I've used that much, and it's hell. I like to stay around 600 a day, which is HOT but safe and effective. Take caps even hours apart through the day, ending about 4-5 PM.

SECOND GUIDLINE...How to eat on DNP. This is purely personal experience, because some guys like to carb-deplete *before* using DNP (then eat carbs as usual while on), and other guys like a low-carb approach throughout. Both are fine. Using DNP is the only time that fructose is a desireable cutting carb, because it keeps the liver replentished. That reduces lethargy and spares muscle.
Be aware that eating high-carb foods WILL increase the heat sensation within an hour, and last about 2 hours. That means don't eat carbs before bed unless you want those night sweats to be even WORSE.
Personally, I ate whatever the hell I wanted! IHOP, chinese, fajitas...Yes, I burned hot, but I still lost 1.5 pounds every 2 days. Keep protein HIGH for muscles' sake, and try it yourself.

Foods I suggest including:
Blueberry yogurt. Blueberries are excellent antioxidants, and yogurt cultures help with digestive function, gas, and stool consistency (disgustingly soft stools are common during DNP).
Oregano-based foods. Oregano is perhaps one of the most potent antioxidants around,a nd one spoonful counts as a vegetable serving. See this article
Pineapple - I've found that pineapple helps alleviate those "DNP Blues". The fructose helps, and pineapple enzymes aid in protein digestion.
V8 - one 12-ounce can supplies six servings of veggies, concentrated as an excellent source of antioxidants, lycopene, and recovery of electrolytes.
Oatmeal - high-fiber foods are necessary. You'll find out why around, oh, day 5 or so. Trust me.


THIRD GUIDELINE...Supplements and DNP. I suggest:
ECA - DNP is not a stimulant. To keep energy high and aid in fat loss, use an ECA. Some advisors suggest that regular ephedrine is preferable to norephedrine because of the more direct "hit" of energy.
Prohormones - perfectly fine on DNP. I used 1-AD just to help keep strength and muscle up, and it worked fine. No problems here. You won't GROW muscle on DNP, but it'll help with strength and protection.
Obvious stuff - multivitamin, ZMA, etc.
Biotest PowerDrive - No, I'm not pimping Biotest. But PowerDrive is an excellent pre-workout mixture that actually works. Plus it's low-carb (only 15 calories total), so it won't cause carb-heat in the middle of your workout.

Antioxidants - I'm giving my own personal list, and why I use them:
Alpha Lipoic Acid - aids in fat management and blood sugar, and an excellent antioxidant.
Grape seed extract
Syntrax Radox
Green Tea
Inositol - mood enhancement, antioxidant, and muscle support. 1 gram/3x day
Ellagic acid - protects cell DNA/RNA from damage by free radicals, and may even atack cancerous cells. 400mg/twice a day
Fruit antioxidants - beyond-a-century's powder of high-potency natural fruit anti's. 1 gram, 2-3x day.
Trimethylglyceine - antioxidant, helps move fat and blood lipids into the liver and out of the body. 500mg, 2x day.
Vitamins E and C

Supplements NOT to use:
Any medications that suppress energy. No allergy meds, antidepressants, muscle relaxers, or beta blockers. DNP will have you low as it is; don't worsen your body's energy by taking something that suppresses you further.

DRUGS - Sheesh, you'd think I wouldn't have to mention this, but two idiots in particular (right here on this forum) recently affirmed that some people still just don't get it. NO alcohol (not even "moderate"), NO ecstasy, NO GHB, etc. If you don't have the willpower to forego these habits, DNP is not for you.

Syntrax Swole - a personal discovery. I tried Swole while on DNP...once. Two hours of hell, feeling inside-out.

FOURTH GUIDELINE...working out on DNP. Keep lifting short, 30-40 minutes. DNP works very well, causing your body to use 150% or more the calories per action you'd normally use. That means DON'T try to repeat your usual workouts. Drop to moderate weights, 8-12 reps, not to failure, and with plenty of walking rest between sets. You are NOT going to grow muscle on DNP, so don't use your usual heavy routine. Since DNP can cause light-headedness and heat dizzyness, you have my permission to skip squats in favor of leg presses this time.

Cardio is a controversial one. My advice - do NOT do cardio on high doses of DNP (600mg or more). It's dangerous and counterproductive. Below that amount, some cardio is fine, but keep it to 20 minutes and not at full-gallop. Remember, DNP will drain water from your quickly, causing you to leech out minerals, vitamins, and salts. Don't overdo it.

During exercise, consume at least 1 liter of water per 30 minutes of work, whether you're thirsty or not. DNP is evil in the way it blunts thirst, while at the same time doing the cruel trick of bloating your body with water WHILE dehydrating you from water in your organs. MAKE yourself drink. Always folllow DNP exercise with antioxidants, carbs, and this is a good time to use your multivitamin.

Don't feel embarrassed about poor workouts. Just this morjning I did a workout with a whopping nine sets (wimp!) before calling it quits. Listen to your body, and let it tell you when enough's enough; don't guage workouts by what you *usually* can do otherwise.

Here's my research. This is AMAZING! Not only has not a single test found it to be carcinogenic, but test after tyest after test find that DNP actually ATTACKS cancer cells, and helps anti-cancer medications work better, and helps anti-leukemia medications work without destroying cell DNA, and suppresses tumor growth by 20-50%. The summaries are all right here, friends. Karma me up!

DNP is Ames negative, and does not promote tumors. See for yourself at http://toxnet.nlm.nih.gov/

http://www.epa.gov/ttn/atw/hlthef/dinitrop.html (2,4-Dinitrophenol | Technology Transfer Network Air Toxics Web site | US EPA) reports on health risks. While there have not been human studies, animal studies found no cancers caused by DNP administration. It is considered a toxin because it causes nausea, sweating, and weight loss.

Cyberiron.com reports on halth risks from external exposue. In other words, don?t get it in your eyes, or on your skin if you?re allergic. Pretty elementary stuff.

http://www.ebec2000.com/abstracts/056.htm This animal study documents a 64% increase in metabolism. "These findings confirm that DNP effectively increases metabolic rate..." Duh.

Biosource A PDF file about an antidote to DNP.

http://www.boehringer-ingelheim.es/...glesa/cap13.htm finds that DNP did not activate liver enzymes (MAT) associated with liver damage

"Comparative study of toxicity of 4-nitrophenol and 2,4-dinitrophenol in newborn and young rats." Koizumi M, Yamamoto Y, Ito Y, Takano M, Enami T, Kamata E, Hasegawa R. Division of Risk Assessment, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan. This study found that DNP can induce death in overdosed amounts, but that up to that point no toxicity was evident, nor were there any abnormalities in physical development.

"Phenol toxicity and conjugation in human colonic epithelial cells." Pedersen G, Brynskov J, Saermark T. Dept of Medical Gastroenterology, Herlev University Hospital, Copenhagen, Denmark.. This study found that DNP has a toxic effect on cells of the colon, with "toxic" defined in two ways: first, it interfered with metabolism (this we know?it?s the intended effect of DNP users!) and second, it interfered with bowel inflammation (not a health risk. This is caused by osmotic effect, with the worst results being softened stools and gas).

"Mechanisms of bacterial resistance to macrolide antibiotics." Nakajima Y. Division of Microbiology, Hokkaido College of Pharmacy, 7-1 Katsuraoka-cho, Otaru, Hokkaido 047-0264, Japan. This study found that antibiotic-resistant bacteria could be thwarted with DNP. "the extent of the accumulated drug in a resistant cell increases as much as that in a susceptible cell in the presence of an uncoupling agent such as?2,4-dinitrophenol (DNP)."

"Absence of Crabtree effect in human melanoma cells adapted to growth at low pH: reversal by respiratory inhibitors." Burd R, Wachsberger PR, Biaglow JE, Wahl ML, Lee I, Leeper DB. Departments of Radiation Oncology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA. Check this out?DNP actually helps make melanoma tumors easier to attack by increasing ratio of oxygen consumption to lactic acid production, while glycolysis remains the same. "Therefore, tumor acute acidification and oxygenation can be achieved by exposure?"


"New insights in the cellular processing of platinum antitumor compounds, using fluorophore-labeled platinum complexes and digital fluorescence microscopy."
Molenaar C, Teuben JM, Heetebrij RJ, Tanke HJ, Reedijk J. Department of Molecular Cell Biology, Leiden University Medical Centre, The Netherlands. DNP is used as a control in tests of antitumor cells because it does NOT bind to cell DNA, nor promote tumors, yet its staining abilities enable tracking of the uptake of antitumor drugs.

Specific inhibition of breast cancer cells by antisense poly-DNP-oligoribonucleotides and targeted apoptosis." Ru K, Taub ML, Wang JH. Department of Biochemistry, State University of New York, Buffalo 14260-3000, USA Are you ready for this? DNP actually INHIBITS (!!!) breast cancers! Yes, not only does it NOT promote cancers, it?s being recognized as a cancer-fighter/blocker. "Two membrane-permeable and RNase-resistant antisense poly-2'-O-(2,4-dinitrophenyl)-oligoribonucleotides (poly-DNP-RNAs) have been synthesized as inhibitors of human breast cancer?fluorescence assay indicates that the targeted antisense inhibition by poly-DNP-RNAs leads to apoptosis of SK-Br-3 cells but does not affect nontumorigenic MCF-10A cells. The control poly-DNP-RNAs with random or sense nucleotide sequence are completely inactive." Plain English? DNP can be synthesized as an anti-cancer compound, because tests show that it blocks mutagens but does NOT affect non-mutagenic (healthy) cells, and has no RNA effects on them.

"Heat shock protein induction by certain chemical stressors is correlated with their cytotoxicity, lipophilicity and protein-denaturing capacity." Neuhaus-Steinmetz U, Rensing L. Institute of Cell Biology, Biochemistry and Biotechnology, NW II University of Bremen, Germany. The thermic effect of DNP induces protein synthesis (heat shock protein, or HSP, synthesis). In fact, it?s quite GOOD at it: "ASA, DNP and CCCP induced HSP at lower concentrations than substances with a similar lipophilicity?"

"Comparative effects of the metabolic inhibitors 2,4-dinitrophenol and iodoacetate on mouse neuroblastoma cells in vitro." Andres MI, Repetto G, Sanz P, Repetto M.
National Institute of Toxicology, Seville, Spain. In this study, DNP?s observed effect was an increase in metabolism (duh!), while the other toxins compared to it had harmful in vitro effects but no increase in metabolism.

"Inhibition of uncoupled respiration in tumor cells. A possible role of mitochondrial Ca2+ efflux." Gabai VL.Medical Radiology Research Center, Russian Academy of Medical Sciences, Obninsk. DNP not only does not cause tumors, but it inhibited their respiration by 20-25% compared to controls.

"Amsacrine-induced lesions in DNA and their modulation by novobiocin and 2,4-dinitrophenol." Shibuya ML, Buddenbaum WE, Don AL, Utsumi H, Suciu D, Kosaka T, Elkind MM. Department of Radiology and Radiation Biology, Colorado State University, Fort Collins 80523. In this study, researchers found that DNP abrogates?or disrupts?cytotoxicity in hamsters (using cancerous cells). They expected to find that DNP would interfere with anticancer treatments, but instead found that DNP increased their effects. They state, though, that they cannot claim a proven effect of DNP on anticancer treatments yet, although they do agree that treatment with DNP actually enhanced the effects of the DNA regenerative therapy of anticancer chemotherapy.

"Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note." Kaufmann SH. Oncology Center, Johns Hopkins Hospital, Baltimore, Maryland 21205. The authors warn that certain anti-leukemia drugs resulted in "extensive DNA degradation." BUT (good ol? DNP to the rescue!), "Preincubation with dinitrophenol abolished the effect?"

"[Dependence of the nature of the action of metabolic inhibitors on ribosomal RNA synthesis in Ehrlich ascites carcinoma cells on cell integrity]" [Article in Russian] Akhlynina TV, Buzhurina IM, Panov MA, Rozovskaia IA, Chernaia NG. DNP actually inhibits the synthesis of RNA in carcinoma cells. In other words, it helps cancerous cells commit suicide by neutering themselves. "Ribosomal RNA (rRNA) synthesis in the intact Ehrlich ascite carcinoma cells is selectively inhibited by papaverin (ED50 = 0.01 mM), 2,4-dinitrophenol (DPN; ED50 = 5 microM), and actinomycin D (ED50 = 0.1 microgram/ml)."

"Autocatabolism of surface macromolecules shed by human melanoma cells." Bystryn JC, Perlstein J. Cancer Res 1982 Jun;42(6):2232-7. This study finds that DNP helps melanoma cells die (autocatabolize) while other cells are unaffected.

http://www.geocities.com/byggdegstor/dnpforside - tons of research, including medical studies. Excerpts:

DNP does not cause liver damage: "Their analyses demonstrate, beyond a doubt, that the liver does not suffer any damage in the course of dinitro treatment." (Biological Study of Dinitro Drugs in Humans By Dr. Jacques Bell. Bell, Jacques. 1939. Etude biologique des produits dinitres chez l'homme. Medecine. 19:749-54. Translation ? 1996 Robert Ames)

Also: "Experimental studies on animals do not show toxic effects of dinitrophenol on the kidney. Anatomical-pathological examinations of animals, even those which died from a massive dose of dinitrophenol, do not reveal any important anatomical changes, except a small degree of cytolysis. Clinical documents are not abundant, but, on the whole, do not seem to demonstrate that dinitrophenol is toxic for the kidneys."

"Dinitrophenol has almost no action on the blood cholesterol. (Grant and Schube)."

"it doesn't seem that dinitrophenol at usual clinical doses is likely to harm the kidneys."

"Dinitrophenol is remarkable for its absence of effect on the cardio-vascular system...dinitrophenol is absolutely devoid of toxicity for the heart."

"Dinitrophenol does not attack cell tissue albumin and does not determine the fat loss to the expense of the muscles, contrary to thyroxine."

"dinitrophenol offers this precious advantage that the cessation of its use at the slightest appearance of signs indicating an imminence of intoxication results immediately in the arrest of those symptoms." (Professor Pouchet)."


Interestingly, one medical theory on a health ADVANTAGE of DNP is that the slight increase in thermogenic temperature simulates the fever a body induces during a viral attack. The body increases itsheat to protect organs but kill viruses, and some theorize that DNP can do the same thing, thus killing viruses in the body. In this mechanism, DNP may have an immune-enhancing effect.
 
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Anyone experience side effects at different times? Usually I feel fatigue and increased appetite long before I feel the heat. First 3 days of a cycle I'm on 200 mg, then 300 mg a day for the rest of the cycle. By the second day, I usually feel lethargic and unreasonably hungry (ADD meds notwithstanding), but I don't usually get night sweats until my first night on 300 mg. Is that normal, or is it all in my head? Maybe I just expect DNP to make me hungry and tired, so it does?

It's kind of getting in the way of things. I end up wasting my precious DNP because I overeat throughout the cycle and lose no weight. It's cool though, in a way. I could be the first person ever to not lose weight on a DNP/amphetamines combo.

The few times I have made it through a 2-week cycle without fucking up my diet, I lost 6 pounds in those 2 weeks. That was on 1100-1200 cals a day. I don't remember the side effects showing up so early.

Get some 21 mg transdermal nicotine patches,great 24-7 anorectic and it's non-stimulatory.

Oh yeah,and send me some of your ADD meds........half joking/half serious lol.
 
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Anyone experience side effects at different times? Usually I feel fatigue and increased appetite long before I feel the heat. First 3 days of a cycle I'm on 200 mg, then 300 mg a day for the rest of the cycle. By the second day, I usually feel lethargic and unreasonably hungry (ADD meds notwithstanding), but I don't usually get night sweats until my first night on 300 mg. Is that normal, or is it all in my head? Maybe I just expect DNP to make me hungry and tired, so it does?

It's kind of getting in the way of things. I end up wasting my precious DNP because I overeat throughout the cycle and lose no weight. It's cool though, in a way. I could be the first person ever to not lose weight on a DNP/amphetamines combo.

The few times I have made it through a 2-week cycle without fucking up my diet, I lost 6 pounds in those 2 weeks. That was on 1100-1200 cals a day. I don't remember the side effects showing up so early.

Holy crap, girl. . .how much do you weigh now? 100? 110? :confused: (Sorry if you said it way back in another post. . .) I mean, I know the DNP can make you hungry, but the fact that you're only consuming 100 cals is NOTHING. I lose eating 1600 - 2000 and I started at 140 (I'm 130 now). I wonder if you upped your cals (cleanly, of course) and ate on schedule, if you'd be less hungry and thus, lose better/not waste the DNP. (Sorry if I sound condescending. I don't mean to. I just saw 1100 cals and though "HOLY SHIT!")
 
LOL, don't worry, it's not condescending. I weigh 115-118, but I'm only 5'1" so I have the metabolism of a post-menopausal sloth. These days I only have time for the gym on weekends, since I commute from Baltimore to DC for work, which takes up 3 hours of each weekday. To maintain my weight, I guess I'd need about 1500 cals a day. Yeah, being the size of an 11-year-old blows, but that's life. I assume most people still eat below maintenance level on DNP, yes?

ADD meds don't live up to the hype, in terms of suppressed appetite. Especially now that crappy generics have taken over the market.

Get some 21 mg transdermal nicotine patches

That was sarcasm, right? I've heard nicotine is, like, bad for you. I'd probably get addicted to the patches. Is nicotine really an appetite suppressant? I thought that was a myth.
 
That was sarcasm, right? I've heard nicotine is, like, bad for you. I'd probably get addicted to the patches. Is nicotine really an appetite suppressant? I thought that was a myth.

No, they are right. The patches and even the gum not only supresses the appetite, but even speeds the metabolism to a small degree, but you can do that by eating on a schedule like stated above
 
. I assume most people still eat below maintenance level on DNP, yes?

ADD meds don't live up to the hype, in terms of suppressed appetite. Especially now that crappy generics have taken over the market.

That was sarcasm, right? I've heard nicotine is, like, bad for you. I'd probably get addicted to the patches. Is nicotine really an appetite suppressant? I thought that was a myth.


Add meds work very well as anorectics (generics included,as long as you're not getting them from shady overseas sites),intil the stimulation wears off.

That is where nicotine comes in.And yes,you definitely should use a deficit with DNP,500kcals will suffice.Don;t expect to eat maintainence kcals and lose an appreciable amount of weight just because you have DNP in you,diet is still key.

Great article on nicotine,for our purposes,only problem is that is slightly increases insulin sensitivity,which can be negated with supplements like Sesathin and fish oil.

http://www.mindandmuscle.net/articles/andrew_novick/nicotine (Chemically Correct: Nicotine | Mind and Muscle)
 
you definitely should use a deficit with DNP, 500kcals will suffice.

Well, maintenance for me is 1500 cals, so a 500-cal deficit would bring me down to 1,000 calories a day. Usually I can swing that, but on DNP, I can't restrict to that level.

Everyone responds to stimulants differently. I take dextroamphetamine, and it does suppress my appetite to a degree. But DNP seems to override that. Nothing can stand up to DNP, it seems.
 
Not sure if I should start another thread or not but was wondering if anyone else running dnp has lost their sense of taste?

I've just finished my 3rd course - done 2 weeks on quite high doesage - the last week was quite hellish I have to say, no sleep, no energy, bad throat all the stuff you would expect but after a week I started to notice I was loosing my sense of taste, well I can say for sure its defo not right - everything tastes bland, chocolate, salty food, cerials they all taste the same.

Now I guess it will come back & as I'm only 3 days out I aint worried but just wondered if anyone else had experienced this??

Mucho thanks :)
 
You're not the first person I've seen with that issue. I didn't experience it myself but other people have reported that it usually comes back within a month or so.
 
Thanks for the reply - I didn't get it the first couple of times either but then they were lower doseages so maybe thats why.

I did read in one of the many DNP guides 'all food apart from carbs taste bland' I guess I'll just have to wait & see what happens. Though I could probally live without taste I'll be so happy when I can sleep again & back to gym tommorow & 3kg's down yay :D
 
Not sure if I should start another thread or not but was wondering if anyone else running dnp has lost their sense of taste?
It's called dysgeusia. It's a very rare side effect of DNP, one that was mentioned in the original clinical research in the 1930's. Dysgeusia might be a special form of a rare side effect of DNP called neuritis (inflammation of the nerves) . The good news is that it's only temporary. Your sense of taste should come back after going off the DNP. In the meantime, I'd make the most of it. The last person I knew with this problem said that the loss of taste made it easy to keep his diet in check, since the foods he craved didn't taste much different than health foods, so he might as well eat healthy.

Good luck,
Conciliator
 
It's called dysgeusia. It's a very rare side effect of DNP, one that was mentioned in the original clinical research in the 1930's. Dysgeusia might be a special form of a rare side effect of DNP called neuritis (inflammation of the nerves) . The good news is that it's only temporary. Your sense of taste should come back after going off the DNP. In the meantime, I'd make the most of it. The last person I knew with this problem said that the loss of taste made it easy to keep his diet in check, since the foods he craved didn't taste much different than health foods, so he might as well eat healthy.

Good luck,
Conciliator

Hi Conciliator - thanks for that info I appreciate it - I'm now a week off of the dnp but still can't taste much - its very true that everything tastes quite bland & boring but I keep buying chocolate bar each day now just to see if I can taste it yet lol [:o)]
Thanks again for the advice :)
 
My night sweats have been getting crazy! Today is day 10 @ 200mg and I'm running out of pillows to flip to get to the cooler side. I didn't have the sweats this bad last time and I am running low carb. Weird and just a passing comment I needed to add for some reason.
 
Hey all, I have a question regarding the characteristic side-effects of DNP. I have read through many boards, and still feel that my question has never completely been addressed

Okay, so I am on day five of my first cycle at 200, 300, 400, 400, 400mg. I know the recommendations of 200mg for 4 days, etc, but I doubted the credibility of my source, and amped it up to the 400mg level by day 3. I do not plan on increasing it further, I am careful and mindful of the risks to say the least. But that is not my question. I have been getting fairly hot, feeling fairly tired, and very bloated. The heat has noticeably increased in the last day. But, drumroll,

I have not been sweating above normal levels! The heat is bearable, but noticeable, and along with the other sides and the tracking quality of the DNP caps, I know my stuff is the real deal, maybe under dosed, but definitely legit. I got it in 100mg caps, and not domestically. But why am I not SWEATING MY ASS OFF?

I know the sides are supposed to get worse and build up in your system. They have, a little, and I am still patiently waiting for them to do so even more. But does it make sense that I can be 98.8 after carbs today, 2 degrees higher than my usual temp, feel like I'm permanently embarrassed, and not shed an extra drop of sweat? Feedback would be greatly appreciated, not because I am a loose cannon and thinking of upping the dosage, but because i am new and genuinely curious about my body and how it might be handling this stuff differently than most.

Also, without the sweating, can the DNP still be working and burning fat? Is the sweating proof of the fat being burned, or just a symptom the internal process, one that might be negated if, say, I radiate heat differently, or if all the vitamins and antioxidants I'm taking have a countering effect? Oh, by the way, I sweat up a storm when I run, and when I hit the sauna on a normal day. Have not tried either on cycle (sauna would be suicide haha), but just saying, I am capable of sweating buckets. Please let me know if I am just being stupid (if thats the case, thats all I need to hear), or if there might be some rational explanation for my lack of this common side
 
Not everyone sweats the same amount and not everyone is really affected by the heat. Especially at this time of year. I ALWAYS try to do my DNP runs in the winter as I really dont feel anything but a little warmer than normal. Now, if it was the summer, that would be a different story as I would be sweating all the time. Also, when I bumped the dose over 400mgs I noticed a HUGE difference in the amount I was sweating. Its not needed to lose weight. Also, you sweat when you are properly hydrated. If you are bloating bad, then you are not hydrated enough. Get more water in throughout the day. It might HELP you to sweat (or at least shed some water) but dont look at it as the main factor to if its working. If your warm, then its working. Also, be ready for the next two days as you will get hotter than you are now
 
thanks bigbench!- its nice to be an absolute newbie on this forum and get thorough answers like that!

i have been keeping things pretty consistent over the last couple days, and have been feeling the heat a bit more consistently. the sweating is still barely above normal levels, but the fatigue, increased temperature, and everything else tell me that it is working its magic. i don't know where you are living, but I'm in Southern California, and it's not boiling or anything, but definitely not the typical 'winter' synonymous with a blissful DNP cycle. But, funnily enough, that is how it has been for me thus far:

I can deal with feeling almost bedridden 2 hours after I wake up, and deal with feeling feverish on occasion, and with the below par but adequate workout I had today. I remember Conciliator saying something in one of the forums about knowing people who run cycles on 800mg and barely sweat, because of an uncommon tolerance for the substance...I do not know if an increased tolerance is the case for me to some extent, but I am happy with how it's going down so far as long as it is burning fat, and I can't see how it couldn't be at this point... right now my only concern is it seems too good to be true, I did my homework but was fearing 2 weeks of hell, and right now it just feels like I have lied out in the sun a bit too long. i will up up the dosage a wee bit, and hope it kicks me on my ass a little bit! At the end of my cycle, I think I will have a clear picture of my personal dosage to progress to side effects ratio
 
Hi again people - its so good to read about other peoples experiences on dnp as I really think I must be one of the few people with an amazing tollerance to dnp - I mentioned quite a way back in this thread about my first experience with dnp was with Alins 200mg caps which I thought must have been underdosed. I ordered some pure DNP powder to cap myself but was sent 2 kinds - a pre mixed dnp/cornstarch powder which I worked my way up to 2 grams a day on this stuff, yeah I got hot and my lifting wasn't as good, cardio suffered but I was fine really & no one noticed anything out of the ordinary - The other powder is apparently 100% pure dnp - after starting at 200mg a day and feeling nothing after a few days I upped it to 400mg then 600 then I was taking 400mg every 12 hours for over a week - I got the sides then oh yes indeed, sweating, out of breath even, walking & talking at same time was crazy hard - sleeping was impossible,sore throaght, lifting weights was pretty much out of the question but I did 8 days like this and apart from I seem to have lost my sense of taste - within 2 days of finishing I could run, lift, sleep etc just like before. I must be one of the few people with a strong tollerance to dnp as I am a 69kg female! I'm not saying any of this to show off in any way as its not really a good thing that I have to take such larges doses to get any effects + its expensive but more to show that everyone is obviously very diferent so not to get too stressed if your not getting the same effects as everyone else & obviously stay safe & never take anything for granted. :)
 
Question to you guys that have used DNP more than once.

Some background first:
I started DNP at 100mg for the first 5 days to test my tolerance. Then I went to 200mg for 5 days. Then went to 300mg for 5 days. Then went back and forth between 300mg and 400mg for another 12 days. Went from 222 to 210 lbs. I was very pleased with the outcome.

Question:
If I were to use DNP again, would it be advisable to start at 300mg the first day based on my first cycle results and tolerance? Thanks.
 
Question to you guys that have used DNP more than once.

Some background first:
I started DNP at 100mg for the first 5 days to test my tolerance. Then I went to 200mg for 5 days. Then went to 300mg for 5 days. Then went back and forth between 300mg and 400mg for another 12 days. Went from 222 to 210 lbs. I was very pleased with the outcome.

Question:
If I were to use DNP again, would it be advisable to start at 300mg the first day based on my first cycle results and tolerance? Thanks.
My recommendation for where to start dosing is the following:

1) If you're using a different DNP product than you did on your last cycle, then treat it like it was your first cycle. This means starting at the lowest dose possible and slowly working up, just like you did with the cycle you described above. This is because you probably don't know how accurately dosed your new product is, and you want to slowly increase the dose in case it's overdosed compared to what you were taking before.

2) If you're using the same DNP product, then drop one to two doses below the highest dose you used during your last cycle. This is because as a DNP cycle goes on, you become more tolerant to it, so a dose that was fine at the end of a cycle is probably a little too high to start with.

liteweight , if you were alternating between 300 and 400mg at the end of your last cycle, and if you're using the same DNP product as before, you shoud be fine starting your cycle at 200mg/day. 300mg/day would probably be alright, but when in doubt, always err on the side of caution. I'd start at 200mg/day and work up from there.

Hope that helps,
Conciliator
 
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