Right. Which is why nighttime injection makes most sense. Besides, who the hell wants to be half asleep all day.. or... napping mid day?
And we're already taking AAS. Why confuse the body further?
MESO-Rx
Anabolic Steroids
A GH and fat loss protocol (rhGH lipolysis) that is science-based
- Thread starter Type-IIx
- Start date
And we're already taking AAS. Why confuse the body further?
scientifik
Member
Yes, I got same letargy that I had when using. Superdrol which I will never touch again for his high side effects
Type-IIx
Well-known Member
Yes, nighttime administration is the sort of default case. If not using specifically for lipolysis or anabolism (those are distinct use cases), people should just go with nighttime/pre-bed.
I don't have any lethargy at the moment, that was my experience on past usage of HGH.
I'm using a different brand at the moment and I haven't experienced any lethargy but I do pin before bed so hard to say ahahah.
In your opinion how much someone lose using HGH before bed compared to the protocol you explained in this thread?
Same, but as stated above I only pin before bed so I don't know if It could work during the day.
I have been always worried of eating the hours after my HGH pin, because I thought it would increase my insulin resistance and hinder the HGH effect, add this to being a zombie during the day if pinning in the morning and that's why I always pin before bed
Are you saying that pre-bed administration will not achieve any lipolysis or anabolism?
Type-IIx
Well-known Member
It certainly will, it's just a middle-of-the-road sort of effect, not taking advantage of using FFAs as energy substrate/fuel to perform work and not maximizing muscle anabolism.
Type-IIx
Well-known Member
Well, I wouldn't even view it as a loss per se. It's just that you rely on GH's direct lipolytic effects, of which there are several mechanisms, rather than exploiting the availability of circulating fatty acids to fuel efforts/prevent reesterification.
GuerillaPete
Well-known Member
Yeah but don't the body repair,grow when we sleep?
Understood, so would I administer my GH dose 2 hours before lifting then? I usually have a meal right before I lift, do you see any issues with this?
Type-IIx
Well-known Member
No issues, if you need to be fed before training for performance go ahead with this. The concerns with respect to feeding after a bolus relate to blood glucose elevations and really more to secretagogues (where efficacy can be reduced).
Klimmzugernie
Well-known Member
It raises the conversion from t4 to t3.
T3 will be elevated by HGH.
The increased need of t4 is the reason that HGH reduce t4 levels.
It can make sense to supplement t4 while on HGH due to obvious reasons.
This has to be controlled by bloods after some weeks.
If HGH consumption is moderate the thyroid is maybe able to cover the increased demand. Depending on the individual
So it causes the thyroid to become overactive? Would supplementing t4 prevent this?
HB_22
Well-known Member
Go and do blood work before you supplement T4. I am taking 3* 2IU per day and my T3, T4 and TSH is perfectly fine.
Klimmzugernie
Well-known Member
Underfunction because of the higher t3 metabolism and insufficient t4 levels and therefore higher TSH.
But as @HB_22 sad it depends from a lot of factors and you have to take bloods. Maybe you have to do nothing
Type-IIx
Well-known Member
People seem to always be looking for excuses to add drugs. GH increases peripheral/extrathyroidal T4 to T3 conversion. There'll be a slight (still within healthy range) decrease in T4 (with concomitant increase in free T3). This is fine and good. If T4 does fall out of range, it's because you were previously undiagnosed hypothyroid. RhGH does not cause but may reveal preexisting central hypothyroidism.
Thanks, I was diagnosed with Graves’ disease when I was a teen, but in my most recent bloodwork done last month all my thyroid markers were in range.
Yeah my most recent bloodwork shows app
My thyroid markers are normal, so I think I’ll just stay the course. Started with 4iu/day, so I’m gonna stay at this for awhile and see how it goes.
Type-IIx
Well-known Member
The GH-IGF-I axis plays a role in the pathogenesis of gynecomastia & estrogens are synergistic (by increasing breast cell expression of IGF-I receptor). IGF-I is directly stimulatory of gynecomastia, while GH receptors have been identified in human breast cell lines, and GH may stimulate growth directly through these, or through lactogenic receptors, as well.
So a SERM/AI may help if estrogens are involved in its pathogenesis for you but this may not hold true universally, as GH & IGF-I (the former probably & the latter definitely) are directly stimulatory as well.
Similar threads
