Arent we mistaken about DNP?

[Petarosus188]

Hey guys,
I was thinking for a while.... arent we confused about DNP. What I mean is dosage!
You can find out literature from the very beginning recommending very high doses....and thats combined with Dan Duchaine recommending going up to 1000mgs. All of these crazy doses are associated with extreme fat burning effects...combined with terrible potential side effects.

Now for a second imagine...if Duchaine would do something like that with Clen. He would introduce it to BBing industry, and would recommend starting at 160 - 200 mcgs!!! Yes we would see very aggressive fat burning and thermogenic effects...combined with terrible side effects!!

Why not just use 100mgs? Molecule still exerts its effects.....of course not so drastically fast....but with much less side effects. Why arent we just patient and use dose...that I read recently, with Vitamin C will probably not exert any cataractogenic effects? Just 100mgs of DNP; 25mgs of Ephedrine and later little T3 to combat suppresion caused by DNP...and use it longer.

What do you guys think?

Also one question: Did anybody here (male) actually developed cataracts?

 

[narta]

DNP is a niche tool, nothing more, nothing less. As with all pharmaceutical tools used in bbing it can be used in a sticky situation. It's not something one should rely on to diet, but if 4lbs of stubborn fat is the difference between 4th place and 1st, why not?

 

[BigTomJ]

Could you explain the bodybuilders not using DNP thing a little more? You guys cut to insane body fat percentages, I’ve heard many stories of bodybuilders fucking up their timing and being behind on a cut, few weeks out from their deadline and they know they gotta drop more than they normally could. Why wouldn’t DNP be deployed at this point? If it’s a show that’s really important to them, why not go for it?

Definitely not trying to argue against what you said, I’m obviously not in the space, just trying to understand the sport better and DNP’s effects on people that are this lean and muscular.

in the event that you are behind in a cut (doesnt usually happen with experienced coaching, messing up a peak has more to do with water retention than not coming in lean enough. not coming in lean enough is usually a first time or newer competitor thing) There are better tools for the job and it would simply be a matter of diving into an even deeper defict in most cases.

in more extreme cases the competitor would be better suited to extending their prep and aiming for a later show, rather than trying to brute force a pre planned show when they arent ready in time (this is the option i more typically see)

 

[ShredSeason]

in the event that you are behind in a cut (doesnt usually happen with experienced coaching, messing up a peak has more to do with water retention than not coming in lean enough. not coming in lean enough is usually a first time or newer competitor thing) There are better tools for the job and it would simply be a matter of diving into an even deeper defict in most cases.

in more extreme cases the competitor would be better suited to extending their prep and aiming for a later show, rather than trying to brute force a pre planned show when they arent ready in time (this is the option i more typically see)

Makes sense! I guess DNP would be the last thing you’d want to add if dropping water was the goal.

 

[Juicedhead]

I cant believe people still use DNP. Isnt that shit likestraight posion? Crazy. Theres many other way better options out there to burn fat. Just my opinion.

 

[Juggy3838]

I cant believe people still use DNP. Isnt that shit likestraight posion? Crazy. Theres many other way better options out there to burn fat. Just my opinion.

2,4-dinitrophenol (DNP) is a mitochondrial toxin. Meaning…. DNP acts in the mitochondrial membrane, uncoupling oxidative phosphorylation and making ATP energy production less efficient. part of the energy that is normally produced from cellular respiration is wasted as heat

 

[Petarosus188]

Makes sense! I guess DNP would be the last thing you’d want to add if dropping water was the goal.

As far as I know from other coaches- causes water retention...and lot of its kick disappears when very low bodyfat is already there. If they mess with it...its to speed up beginning of prep... and then use stims, while receptors are fresh.

 

[AlexDavis43]

I cant believe people still use DNP. Isnt that shit likestraight posion?

DNP is a horrible drug for gym-bro's trying to lose some belly fat in 2024. Like T3 (in this context).

 

[Juicedhead]

DNP is a horrible drug for gym-bro's trying to lose some belly fat in 2024. Like T3 (in this context).

Yeah I guess they had this massive break through in weight loss and fat burning. Its call hard diet and cardio. Apperently it works better than any fat loss agent curently out there.

 

[bilbobagginz101]

BigTomJ's anecdote checks out among the circles I know of, and also my own experience. Though I wouldn't say that DNP is superfluous. It's still a very useful tool - it's just that it's sub-optimal if not far from ideal for contest prep and vodybuilding contexts.

Conversely, where I'm from, I can validate that DNP isn't uncommon amongst models/physique models. Very different aim and end-product there compared to bodybuilding, but it's an asset to those who need to get from lean to shredded fast, where retaining mass, size, and appearing flat aren't nearly as much a priority like they would be on stage.

DNP + Water-fasting/keto + Dry Steroids (moreso for men) is a recipe for getting dicey fast. Also can't forget the amphetamines too for that appetite suppression

 

[Petarosus188]

BigTomJ's anecdote checks out among the circles I know of, and also my own experience. Though I wouldn't say that DNP is superfluous. It's still a very useful tool - it's just that it's sub-optimal if not far from ideal for contest prep and vodybuilding contexts.

Conversely, where I'm from, I can validate that DNP isn't uncommon amongst models/physique models. Very different aim and end-product there compared to bodybuilding, but it's an asset to those who need to get from lean to shredded fast, where retaining mass, size, and appearing flat aren't nearly as much a priority like they would be on stage.

DNP + Water-fasting/keto + Dry Steroids (moreso for men) is a recipe for getting dicey fast. Also can't forget the amphetamines too for that appetite suppression

Oh god what a cocktail...

 

[AlexDavis43]

Also can't forget the amphetamines too for that appetite suppression

Appetite suppression is what 99% of people here need.

 

[bilbobagginz101]

Appetite suppression is what 99% of people here need.

I agree, but suicide cut can only go so fast, and the fat-loss there falls off a cliff as you go sub 10%. 10% to model-esque 6% is a mountain of work that requires a lot of strategies and tools. DNP lets you put that process on rocket-boosters if you do it right.

 

[nightwolf]

I come to you all today for your humble input on this thread:

https://thinksteroids.com/community...t-appropriate-to-post-here-i-think.134427245/

Not sure what "type" of DNP we got but hoping one of you guys would know.

 

[DECLAN]

I come to you all today for your humble input on this thread:

https://thinksteroids.com/community...t-appropriate-to-post-here-i-think.134427245/

Not sure what "type" of DNP we got but hoping one of you guys would know.

If you don’t trust your source and not willing to test it, chuck it and find another another vendor that has tests. That is the safest route you can go.

 

[userhuthuthut]

I’d rather inject heroin than ever consume DNP that’s how awful it is

 

[TA13579]

I understand the motivation to shed some fat and to do it quickly, but after a lot of research on this forum, I decided it wasn't worth the risks. There are several testimonials by forum members of severe side effects.

One in particular was a person that developed cataracts in both eyes and had to undergo surgery at a very young age to restore vision. Any kind of sides that can impact the eyes is a no-go for me. No fucking way will I end up blind. I quoted that person's story below:

I see that this is an old thread. But if anyone gets to this comment, ITS A HUGE RISK. I took a few rounds of DNP and lost a ton of weight before GLPs. I was doing 250mg for a while and then bumped it up to 500mg. It felt like I was at deaths door each time. But I was a dumb ass and kept at it. I couldn’t tolerate any temps higher than 50-60 degrees and was sweating at my job which was embarrassing. Then I noticed my feet burning. I had to hold ice to them. This was the first sign of peripheral neuropathy. My feet felt heavier and heavier and got super numb. And the last thing to happen was cataracts. I was on my first month of my last cycle and noticed my vision getting hazy and stopped DNP immediately. And within one more month I was completely blind. Im a surgery coordinator for an eye surgeon so I was able to have surgery myself on both eyes at the age of 30. I’m probably the 3rd youngest patient we had seen in years. Good side is now I have super vision and can see without glasses.

Taking GLPs alone is way better. It does its job. It helps with other medical issues. It makes me feel healthy and happy. I lost just as much weight. I’ve been off DNP for a few years now and my feet have healed maybe 80 percent. They are not heavy anymore. They are just numb in the toes instead of the whole foot.

If you’re going to try DNP, try GLPs FIRST.

There does seem to be some scientific research to support this story:

Cataracts Produced by Dinitrophenol

The first report of a cataract developing in man after the ingestion of dinitrophenol was in 1935.1 Six years later Horner2 collected from the literature 177 cases. The cataracts occurred approximately 15 months after the drug was received.3 Horner,4 in 1942, stated, "all attempts to produce...

jamanetwork.com

The first report of a cataract developing in man after the ingestion of dinitrophenol was in 1935.1 Six years later Horner2 collected from the literature 177 cases. The cataracts occurred approximately 15 months after the drug was received.3 Horner,4 in 1942, stated, "all attempts to produce experimental cataracts in laboratory animals by various and repeated doses of dinitrophenol have been unsuccessful." Bellows,5 in 1944, also commented on the fact that ordinary laboratory animals do not develop cataracts when dinitrophenol is given. Krause6 attributed this failure to a difference in the metabolism of the species.

https://www.surveyophthalmol.com/article/S0039-6257(14)00039-3/fulltext

An outbreak of cataracts in 1935 caused by dinitrophenol (DNP), the active ingredient of popular diet pills, highlighted the inability of the U.S. Food and Drug Administration (FDA) to prevent harmful drugs from entering the marketplace. Just two years earlier, the FDA used horrific images of ocular surface injury caused by cosmetics at the World's Fair in Chicago to garner public support for legislative reform. The FDA had to walk a fine line between a public awareness campaign and lobbying Congress while lawmakers debated the need for consumer protection. The cataract outbreak of 1935 was conspicuous in the medical literature during the height of New Deal legislation, but questions persist as to how much it affected passage of the proposed Food, Drug, and Cosmetic Act (of 1938). The legislation languished in committee for years. The cataract outbreak probably had little impact on the eventual outcome, but medical opinion concerning the safety of DNP may have contributed to the voluntary withdrawal of the diet drug from the market. We review the DNP cataract outbreak and examine it in context of the challenges facing regulatory reform at that time.