For whatever reason @readalot has become obsessed with this pet topic of heavy metal contamination of gear.
Thanks for sharing the reddit find. Regarding your comment above (2nd time this week you've tagged/replied to me regarding heavy metals), my answer is the same as last time. Metals just one of the many tests performed to USP standards for Pharmaceutical AAS QC.
Good comments by Jano (thanks for sharing them):
I'd worry much more about stuff such as impurities from degradation (mostly cause PIP), impurities from chinese giving up on recrystallization a little bit too soon, mixed up compounds, residual solvents etc..
I had not read those comments, but the gist sounds familiar:
thinksteroids.com
In particular, maybe you'll enjoy this given your very high IQ:
I‘m here for intelligent debate and await your rebuttal.
Thanks. I too am here for intelligent debate. I find nothing problematic with the analysis you did. It is one example scenario. You'd like a rebuttal but never did clarify where the red herring was. Ok.
Here's a more complete sensitivity analysis including
(1) various solvents that could be present from either synthesis or purification (as a ChE you'll appreciate an UGL may not be using the most innocuous solvent choice)
(2) PDE for the respective solvents
(3) residual solvent content of 1, 2, and 3%
(4) weekly...
IMO, the analysis provided indicates making sure ugl manufacturers aren't cutting corners on residual solvents leftover from chemical synthesis and/or purification is a worthwhile endeavor.
Or maybe this one:
There are probably groups doing this, hence Jano said he had done test for heavy metals and found no indications of contamination.
At some point there was what appears to be a not insignificant amount done. Of course the batch is only as good as the current test. Leaching, corrosion, corners being cut are what need to be guarded against.
However, just like how testing became famous, individuals or group testing were being conducted privately and anonymously at first. It just became more common as an added marketing strategy for vendors as well as a minimum requirement for...
That obsession with heavy metals is really strong with me; gosh, you've got me dead to rights.
So revisiting your comment (which doesn't sound all that sincere; i see your pattern):
For whatever reason @readalot has become obsessed with this pet topic of heavy metal contamination of gear.
I am hopeful you will abandon perpetuating the silliness. How did you miss all this given your
prodigious research skills?
I’ll admit red herring was just a word a threw out there. I’m not doubting that in certain UGL products and in certain individuals there could be a problem. I appreciate the graphs you you made (very nicely done) and I concur that at VERY HIGH doses there could be an issue with certain solvents.
Thank you.
However upon further research it seems that methanol, ethanol，benzene, and pyridinein are the solvents ”usually” used for testC synthesis. Could you run graphs on those?
The solvents I selected above were supposed to be a sample of those used not just for test esters but...
You know it's funny, I was the one conversing with Jano about the possibility of robust residuals solvent testing, which doesnt appear to be widely available to UGL users today.
But tell me more how I am obsessed with heavy metals. Tag me again tomorrow?
Heavy metals?
Come to think of it, I haven't received another one of your entrapment schemes via PM lately. That's been nice. Instead of tagging me about heavy metals tomorrow, maybe whisper on another thread I am LE. That's always a nice touch.
Brandolini's Law sure is a bi*ch.
