Do you plan to blast in old age (40+)?

[OldGHGuy]

I’m 60 and have been using aas for 42 years. Not continuously, but regularly. As I’ve gotten older I pay more attention to blood work (monthly) and take a few drugs to keep everything in or near range. I recently bought a large life insurance policy that required a lot of tests (blood, scans and a stress test). No issues.

My advice
Cardio 30 min every day
Watch bp closely (Telmisartin, nebivolol if over 125)
Use ezitamide, citrus bergamot and fish oil if any lipids are off
Monthly blood work.
Watch glucose carefully.
Get and stay lean (under 10% bf)
Eat a basic bb diet mostly, but enjoy life
Avoid tren and orals

Which drugs have you mainly used (obviously you like Primo) and what does your TRT/cruise and blast cycling look like - dosages, duration, etc.

Someone that has used AAS as long as you and is still in good health has my curiosity piqued. Well done!

 

[egruberman]

Low dose statin takes care of any cholesterol issues with little/no sides (for me at least)

In terms of cheap and easily available poly-pharmacy for lipid management, low-dose rosuvastatin, ezetimibe and bempedoic acid all have complementary effects and will give you LDL (and ApoB) values of a teenager when taken in concert.

I started on ezetimibe with an ApoB in the 120mg/dL range. That plus some dietary modifications and all the various supplements people recommend for such things got me to around 100mg/dL. I added 10mg rosuvastatin daily which got me in the 70s. Bempedoic acid dropped it by another 15% or so. I think it was 50mg/dL before I started a PCSK9i. LDL-C is commensurately low.

Bempedoic acid is hard to get covered in the US and it's ~$300ish per month on goodrx. However, you can order it from any of the Indian pharma places. For example pct.zone has "bempetol" for $.40ea or about $12/mo.

In the past year, the results of a couple of outcomes trials have been published showing substantial evidence not just of a lipid lowering effect, but an actual reduced risk of death.

https://www.nejm.org/doi/full/10.1056/NEJMoa2215024

Cholesterol Lowering via Bempedoic Acid, an ACL-Inhibiting Regimen - American College of Cardiology

Dharam J. Kumbhani, MD, SM, FACC

www.acc.org

The side effects look kinda scary, but the incidence is extraordinarily low.

Repatha is a different story entirely. If you're statin intolerant, get an Rx and apply for the copay card. Being a biologic, I doubt you'll be seeing that come out of India or China any time soon. Inclisiran is another PCSK9i hitting the market soon, but the only benefit to that are fewer injections for folks that don't like the idea of putting a needle in themselves, so, basically nobody here.