Godtropin IGF Bloodwork

[mands]

Just kind of thinking out loud (not making any accusations/claims of inferior product)...could there be some correlation between the decreased bioavailability and the welts some people are experiencing? Maybe something to due with an improper/incomplete filtering process not removing all the bacteria used during manufacturing process? Could something like this cause the red welts or an immune response decreasing bioavailability where the body is actually attacking the exogenous Gh?
Again just looking for thoughts and opinions not making any claims in relation to product quality.

I thought the same thing. I believe the testing did not show any impurities. I could be wrong though. I was thinking along the lines of the welts and if this had any correlation with it behaving differently. I really can't say.

I do remember high amount of GLY being in those GT samples tested. I wouldn't think this would cause any issues like welts at all. Maybe some nausea or stomach pain if anything I'm guessing?

mands

 

[Doug_S]

I thought the same thing. I believe the testing did not show any impurities. I could be wrong though. I was thinking along the lines of the welts and if this had any correlation with it behaving differently. I really can't say.

I do remember high amount of GLY being in those GT samples tested. I wouldn't think this would cause any issues like welts at all. Maybe some nausea or stomach pain if anything I'm guessing?

mands

Analyzer testing showed dimer @ 15% did it not? Was that a different batch?

 

[Jeffg353]

I thought the same thing. I believe the testing did not show any impurities. I could be wrong though. I was thinking along the lines of the welts and if this had any correlation with it behaving differently. I really can't say.

I do remember high amount of GLY being in those GT samples tested. I wouldn't think this would cause any issues like welts at all. Maybe some nausea or stomach pain if anything I'm guessing?

mands

I didn't look at testing performed as I never planned on purchasing this product. However those results came out there's obviously something in it the body is not liking. If there was only a few people getting the welts I could see the allergy/reaction claim but when u have 50+ % of users experiencing it the only logical conclusion is something in the product. It becomes even more evident when these same people don't get the welts from a different brand.

 

[Dr JIM]

However, how a business man like Matt handles this is absolutely ridiculous. He turned tail and ran at the first sign of distress and that is NEVER someone I want to deal with.....

That's discouraging to say the least BUT let's face it some suppliers just can't handle "Meso's drama drama drama", lol!

I

 

[mands]

Analyzer testing showed dimer @ 15% did it not? Was that a different batch?

@Marcus was your product a different batch#?

mands

 

[Marcus]

@Marcus was your product a different batch#?

mands

Nope... same one. But the batch number was provided by GT. He sent a vial to each Analyzer and Jano and then said what batch it's from, so hard to say for certain

 

[ProfessorX]

I thought the same thing. I believe the testing did not show any impurities. I could be wrong though. I was thinking along the lines of the welts and if this had any correlation with it behaving differently. I really can't say.

I do remember high amount of GLY being in those GT samples tested. I wouldn't think this would cause any issues like welts at all. Maybe some nausea or stomach pain if anything I'm guessing?

mands

It's a different test Mands

ENDOTOXINS: (possible red welt reaction - immune response - could effect IGF1)

Bacteria pyrogen such as endotoxins, also called lipopolysaccharides (LPS), are major contaminants found in commercially available proteins or biologically active substances. This bacterial endotoxin is a potent stimulator of the mammalian immune system in vivo, and it may decrease tissue culture cell viability and inhibit transfection efficiency in vitro. This often complicates the study of the biological effects of the main ingredient. Even low levels of endotoxins can be toxic to cells or organisms and must be removed before biological samples can be introduced.

Link:

Endotoxin Testing Analysis and Removal - Bio-Synthesis, Inc.

Maybe @jano or @Analyzer could look into this testing method for the samples they have of this batch

The standard is:

Endotoxin levels to 0.5 EU/µg or less


Also.....IGF1 serums aren't always the best comparison to "quantify" what's in the GodTropin vial.

Maybe Marcus could lower the dose at 4Ius (one dose) and re-test.....just to see

 

[Marcus]

It's a different test Mands

ENDOTOXINS: (possible red welt reaction - immune response)

Bacteria pyrogen such as endotoxins, also called lipopolysaccharides (LPS), are major contaminants found in commercially available proteins or biologically active substances. This bacterial endotoxin is a potent stimulator of the mammalian immune system in vivo, and it may decrease tissue culture cell viability and inhibit transfection efficiency in vitro. This often complicates the study of the biological effects of the main ingredient. Even low levels of endotoxins can be toxic to cells or organisms and must be removed before biological samples can be introduced.

Link:

Endotoxin Testing Analysis and Removal - Bio-Synthesis, Inc.

Maybe @jano or @Analyzer could look into this testing method for the samples they have of this batch

The standard is:

Endotoxin levels to 0.5 EU/µg or less


Also.....IGF1 serums aren't always the best comparison to "quantify" what's in the GodTropin vial.

Maybe Marcus could lower the dose at 4Ius (one dose) and re-test.....just to see

I agree it is not the best to quantify what's in the vial, however I am comparing it to another brand that I took the same dose of and got a score 70% higher just 10 days prior. And while it may not be best to quantify this way, it does help me as a consumer decide what route I'm gonna to go.

The bloods were pulled for my own knowledge but I post them here for others to utilize as they see fit. That's all

Edit: as far as lowering the dose to 4iu, I just am not willing to waste any more time with GT's stuff especially with possibility of underdosing, and then another $60 on IGF test but most importantly finding the time to get to labcorp. I understand things are left open-ended for some, and if that's the case then say "fuck you" to me and discount my bloods, it's really no skin off my back and I understand this mentality. Just run bloods yourselves and see what you like and what works for you (the royal "you," not you professor X)

 

[Marcus]

@mands i have 3 vials of GT left... same ones I tested. I don't trust too many guys here but if you want em, I'll send to you to pin and Test IGF.

 

[ProfessorX]

I agree it is not the best to quantify what's in the vial, however I am comparing it to another brand that I took the same dose of and got a score 70% higher just 10 days prior. And while it may not be best to quantify this way, it does help me as a consumer decide what route I'm gonna to go.

The bloods were pulled for my own knowledge but I post them here for others to utilize as they see fit. That's all

Edit: as far as lowering the dose to 4iu, I just am not willing to waste any more time with GT's stuff especially with possibility of underdosing, and then another $60 on IGF test but most importantly finding the time to get to labcorp. I understand things are left open-ended for some, and if that's the case then say "fuck you" to me and discount my bloods, it's really no skin off my back and I understand this mentality. Just run bloods yourselves and see what you like and what works for you (the royal "you," not you professor X)

Yep

I agree. Lotta time and money for multiple Serum testing

In comparison with the other brand.....it does seem to be a potential issue

I've run comparison IGF1s on different brands myself

Over time....I started seeing some other members not seeing the same results on known legit PHARMA brands and tested Generics.

So....sometimes the IGF1 serums can "range" in results for different individual as @Dr JIM mentioned

But...blood results are appreciated Marcus. I don't blame you about no further testing

It can become an endless black hole

 

[janoshik]

I usually don't start witch hunts and I certainly wouldn't without gathering enough information to back my claims. I didn't start a witch hunt on you. I was the one that actually was glad to have someone with some other testing abilities if you remember. You broke my trust when you gave me some elaborate story when I sent you vials for testing. We are past that.

Not you mands, I never accused you of doing that.

JIM did that and I asked if you approve of that kind of behavior.

Can you explain to me why AAA cannot be used to test HGH please?

I never had such a claim, Mands.

My claim is that such analysis CANNOT be carried out in accurate manner.

I also, DO NOT like your condescending tone jano. I would ask you to watch that for the sake of discussion. I know you are a HOT head and I don't think it's needed here.

He didn't know the exact page... Just to start on page 3 of another thread that he didn't link. You know how many GT threads there are? Again, I didn't make the claim so you are correct. Burden of proof is on you and I am not calling you a liar.

mands

I don't like the very suggestive questions that you ask me as well, but trust me, I'm not condescending at all - just pointing out my observations.

If you don't agree with my observations I'll be happy to hear counter arguments, mands.

I, instead, think, that I'm adhering to factual and very rational line of discussion today right now. Where did I post something that would suggest otherwise?


I think Mr. Doug had now clarified.

Thank you for this reply. It answered all my questions that I needed to know.

...
mands

I'm glad. Thank you for the civil discussion, although I don't think my arguments made an impact.

 

[janoshik]

I thought the same thing. I believe the testing did not show any impurities. I could be wrong though. I was thinking along the lines of the welts and if this had any correlation with it behaving differently. I really can't say.

I do remember high amount of GLY being in those GT samples tested. I wouldn't think this would cause any issues like welts at all. Maybe some nausea or stomach pain if anything I'm guessing?

mands

Glycine would have no effect.

Minute impurities from foreign bodies or endotoxin are NOT detected or picked up by HPLC or MALDI unless the assay is focused on them specifically, though.


//EDIT: just now seen the post of @ProfessorX regarding endotoxin.

Endotoxin is tested for either by LC/MS/MS or with blood of horseshoe crab.

The latter method being significantly cheaper, but way more sensitive to contamination.

 

[janoshik]

Analyzer testing showed dimer @ 15% did it not? Was that a different batch?

That test was conducted 2 weeks (!!) after reconstituting the hormone.

Such reading cannot be considered reliable due to that.

 

[janoshik]

Nope... same one. But the batch number was provided by GT. He sent a vial to each Analyzer and Jano and then said what batch it's from, so hard to say for certain

Correct.

 

[Marcus]

Yep

I agree. Lotta time and money for multiple Serum testing

In comparison with the other brand.....it does seem to be a potential issue

I've run comparison IGF1s on different brands myself

Over time....I started seeing some other members not seeing the same results on known legit PHARMA brands and tested Generics.

So....sometimes the IGF1 serums can "range" in results for different individual as @Dr JIM mentioned

But...blood results are appreciated Marcus. I don't blame you about no further testing

It can become an endless black hole

Yes sir... that was my 3rd one in like 6 weeks on GH, plus another on MK, plus my own on test. 5 blood test in a couple months all for the sake of comparison gets tiresome.

Pharma next though... I am looking forward to that one

 

[janoshik]

Yes sir... that was my 3rd one in like 6 weeks on GH, plus another on MK, plus my own on test. 5 blood test in a couple months all for the sake of comparison gets tiresome.

Pharma next though... I am looking forward to that one

I think you might consider checking out the work of Mr. Racepicks and Mr. Buck1973 over at ProfessionalMuscle if you hadn't already - especially if you are going to do a research of sorts, regarding blood tests.

 

[Marcus]

I think you might consider checking out the work of Mr. Racepicks and Mr. Buck1973 over at ProfessionalMuscle if you hadn't already - especially if you are going to do a research of sorts, regarding blood tests.

I'll check it out tonight. Thanks Jano

 

[mands]

It's a different test Mands

ENDOTOXINS: (possible red welt reaction - immune response - could effect IGF1)

Bacteria pyrogen such as endotoxins, also called lipopolysaccharides (LPS), are major contaminants found in commercially available proteins or biologically active substances. This bacterial endotoxin is a potent stimulator of the mammalian immune system in vivo, and it may decrease tissue culture cell viability and inhibit transfection efficiency in vitro. This often complicates the study of the biological effects of the main ingredient. Even low levels of endotoxins can be toxic to cells or organisms and must be removed before biological samples can be introduced.

Link:

Endotoxin Testing Analysis and Removal - Bio-Synthesis, Inc.

Maybe @jano or @Analyzer could look into this testing method for the samples they have of this batch

The standard is:

Endotoxin levels to 0.5 EU/µg or less


Also.....IGF1 serums aren't always the best comparison to "quantify" what's in the GodTropin vial.

Maybe Marcus could lower the dose at 4Ius (one dose) and re-test.....just to see

Yes sir! I'm seeing that now. I believe other tests have to be made to find Endotoxins other than MALDI.

You are correct IGF-1 serums aren't good for comparison from person to person. I do believe testing different GH sources within oneself is IMO.

Thanks for the post.

mands

 

[mands]

@mands i have 3 vials of GT left... same ones I tested. I don't trust too many guys here but if you want em, I'll send to you to pin and Test IGF.

I believe person to person isn't really a good testing method. I think your testing with the blacks compared to the GT shows that your IGF-1 levels should reach 700 on that dosing.

I'll PM you.

mands

 

[mands]

Glycine would have no effect.

Minute impurities from foreign bodies or endotoxin are NOT detected or picked up by HPLC or MALDI unless the assay is focused on them specifically, though.


//EDIT: just now seen the post of @ProfessorX regarding endotoxin.

Endotoxin is tested for either by LC/MS/MS or with blood of horseshoe crab.

The latter method being significantly cheaper, but way more sensitive to contamination.

I agree thanks for validating on the GLY.

Yes I just saw this and Prof X after posting as well.

mands