HCG degradation testing after 30, 45, 60 days

[pengpent]

@Qingdao Sigma Chemicals are all your products rhCG or just the last batch (with 15000iu)?

 

[Qingdao Sigma Chemicals]

@Qingdao Sigma Chemicals are all your products rhCG or just the last batch (with 15000iu)?

We had 2500IU, 3500IU, 5000IU, 10kIU and 15kIU

Now we have 2500IU in EU warehouse, 3500IU in US warehouse, and 15kIU in US and China warehouse

 

[pengpent]

Thanks @Qingdao Sigma Chemicals
Is only 15000 rhCG and the others are uhCG?

 

[Qingdao Sigma Chemicals]

Thanks @Qingdao Sigma Chemicals
Is only 15000 rhCG and the others are uhCG?

All UGL chinese HCG, is rHCG

 

[lift4lyfe]

All UGL chinese HCG, is rHCG

XCE (rest in peace) confirmed their UGL chinese HCG was urine derived. Was XCE the only UGL chinese lab with urine derived HCG?

 

[lift4lyfe]

All UGL chinese HCG, is rHCG

Is there a way that we can test/confirm that QSC's HCG is recombinant?

@janoshik can you chime in on whether there's a way to confirm with >95% certainty whether a vial of HCG is recombinant or not?

 

[Qingdao Sigma Chemicals]

XCE (rest in peace) confirmed their UGL chinese HCG was urine derived. Was XCE the only UGL chinese lab with urine derived HCG?

I believe he was wrong about the assumption.

 

[janoshik]

Is there a way that we can test/confirm that QSC's HCG is recombinant?

@janoshik can you chime in on whether there's a way to confirm with >95% certainty whether a vial of HCG is recombinant or not?

There's certainly a way but I don't know it... However, I feel we might be past the point when recombinant is cheaper and that's pretty bulletproof indicator for what manufacturers are going to use.

 

[Type-IIx]

There's certainly a way but I don't know it... However, I feel we might be past the point when recombinant is cheaper and that's pretty bulletproof indicator for what manufacturers are going to use.

I want mine to come from urine, or I'm not interested. Same with my GH, I get better pumps and vascularity when I know that a corpse was sliced open for my sake to extract its pituitary gland.

 

[UncleBuns]

I want mine to come from urine, or I'm not interested. Same with my GH, I get better pumps and vascularity when I know that a corpse was sliced open for my sake to extract its pituitary gland.

Lady piss is good for cutting. Hard and veiny guaranteed.

 

[Spaceman Spiff]

Lady piss is good for cutting. Hard and veiny guaranteed.

Keep justifying your golden shower play, you disgusting human being.

 

[UncleBuns]

Keep justifying your golden shower play, you disgusting human being.

Doctors orders. It's just for fertility. Not weird at all. That's what I tell my wife.

 

[ohio117]

XCE (rest in peace) confirmed their UGL chinese HCG was urine derived. Was XCE the only UGL chinese lab with urine derived HCG?

Interesting. When was this? I have XCE HCG that I will probably not use if true

 

[Qingdao Sigma Chemicals]

After 30 days of reconstitution in bacteriostatic water, 0.8% BA, in fridge, almost zero degradation:



After 30 days:

 

[MyNameIsJeff]

We have 2 data points:


Sample...Manufacturer....Excipients.....Reconstitution....30-day degradation
1................Liska.................?................Sterile water.............18.1%
2................QSC..................?.................BAC water................0.9%


Now the question is: Does the BAC water lead to reduced degradation, or the presence of (PH-stabilizing) excipients that may or may not be in the QSC product?

For those who think it's the BAC water: What's the mechanism here? The BAC water prevents the growth of airborne bacteria that otherwise would eat up the peptide hormone? @janoshik, what's your preferred explanation?

 

[Qingdao Sigma Chemicals]

We have 2 data points:


Sample Manufacturer Excipients Reconstitution 30-day degradation
1 Liska ? Sterile water 18.1%
2 QSC ? BAC water 0.9%


Now the question is: Does the BAC water lead to reduced degradation, or the presence of (PH-stabilizing) excipients that may or may not be in the QSC product?

For those who think it's the BAC water: What's the mechanism here? The BAC water prevents the growth of airborne bacteria that otherwise would eat up the peptide hormone? @janoshik, what's your preferred explanation?

I believe the bacteriostatic water reduce degradation, because the product do not have any pH-stabilizing excipients. Only mannitol filler.

 

[Xiaoxiong]

I believe the bacteriostatic water reduce degradation, because the product do not have any pH-stabilizing excipients. Only mannitol filler.

Or could it be the difference between Urine purified and Recombinant HcG?

 

[MyNameIsJeff]

We have 2 data points:


Sample...Manufacturer....Excipients.....Reconstitution....30-day degradation
1................Liska.................?................Sterile water.............18.1%
2................QSC..................?.................BAC water................0.9%


Now the question is: Does the BAC water lead to reduced degradation, or the presence of (PH-stabilizing) excipients that may or may not be in the QSC product?

For those who think it's the BAC water: What's the mechanism here? The BAC water prevents the growth of airborne bacteria that otherwise would eat up the peptide hormone? @janoshik, what's your preferred explanation?

There is actually one more data point from this study I mentioned earlier: The influence of different excipients and storage procedures on hCG (human Corionic Gonadotropin) as evidenced by spectrophotometry - Nature Precedings

Sample...Manufacturer........Excipients........Reconstitution....30-day degrad.
1................Liska.....................?..................Sterile water.............18.1%
2................QSC......................?...................BAC water................0.9%
3................Pharma.......phosphoric acid.....Sterile water.............~0%
......................................&sodium hydroxide.........................................
......................................&Mannitol.......................................................

 

[janoshik]

We have 2 data points:


Sample...Manufacturer....Excipients.....Reconstitution....30-day degradation
1................Liska.................?................Sterile water.............18.1%
2................QSC..................?.................BAC water................0.9%


Now the question is: Does the BAC water lead to reduced degradation, or the presence of (PH-stabilizing) excipients that may or may not be in the QSC product?

For those who think it's the BAC water: What's the mechanism here? The BAC water prevents the growth of airborne bacteria that otherwise would eat up the peptide hormone? @janoshik, what's your preferred explanation?

I honestly don't know, but my wild guess would be living organism induced degradation - while usually insignificant, with Hcg dosed in microgram range it could have more impact relatively.

 

[hungryalways]

There is actually one more data point from this study I mentioned earlier: The influence of different excipients and storage procedures on hCG (human Corionic Gonadotropin) as evidenced by spectrophotometry - Nature Precedings

Sample...Manufacturer........Excipients........Reconstitution....30-day degrad.
1................Liska.....................?..................Sterile water.............18.1%
2................QSC......................?...................BAC water................0.9%
3................Pharma.......phosphoric acid.....Sterile water.............~0%
......................................&sodium hydroxide.........................................
......................................&Mannitol.......................................................

Surprising results in the full text even though it is not relating to BAC water. Zero degradation between 4 and 25ºC. If this is accurate, then traveling with HCG would be MUCH easier.