Hgh length?

Using GH lowers T4 typically. It’s not broscience. Many people have bloodwork showing this. I have to use it when I run GH to keep my levels normal, without it my levels are low, and it is essential to have optimal T4 levels all the time. So supplementing with T4 isn’t just adding more drugs that aren’t essential.

And having low T4 levels means what exactly bro (in health terms) and please do explain how supplementing with thyroid meds is essential when using GH.

I never used any thyroid meds in 10 years of GH use....and 5 out of those 10 years were constant daily GH use.

I'm all ears....
 
And having low T4 levels means what exactly bro (in health terms) and please do explain how supplementing with thyroid meds is essential when using GH.

I never used any thyroid meds in 10 years of GH use....and 5 out of those 10 years were constant daily GH use.

I'm all ears....
 

Spurious and inconclusive but keep popping T4 and/or T3 (or whatever else) if it makes sense in your own head bro.
 
Spurious and inconclusive but keep popping T4 and/or T3 (or whatever else) if it makes sense in your own head bro.
Thats your response? My lab work reflects deficiency in t4 and increase of t3.

The whole thread discusses it. You said you are all ears but you arent looking at people's rationale for it nor are you doing any reading on it.
 
And having low T4 levels means what exactly bro (in health terms) and please do explain how supplementing with thyroid meds is essential when using GH.

I never used any thyroid meds in 10 years of GH use....and 5 out of those 10 years were constant daily GH use.

I'm all ears....
Means you will have trouble burning body fat
 
Thats your response? My lab work reflects deficiency in t4 and increase of t3.

The whole thread discusses it. You said you are all ears but you arent looking at people's rationale for it nor are you doing any reading on it.
At what point did you start the T4?

Could you add the right T3 values?
 
Exogenous T4 is not necessary with rhGH unless one has pre-existing central hypothyroidism (rhGH can reveal central hypothyroidism, but not cause it). The decrement in serum T4 (within physiological ranges) is due to increased peripheral conversion of T4 to T3 (responsible for some but not all of rhGH's increase to RMR).
 
I mean, you have a log of the compounds being used in your bloodworks in your excel but cannot see the T4 on it, what date did you introduce your T4 in?
After I read the thyroid results. I had it on hand and made that call when I saw it. It was probably a day after the first time it was low and added 100mcg at the time
 
After I read the thyroid results. I had it on hand and made that call when I saw it. It was probably a day after the first time it was low and added 100mcg at the time
So after the last bloodwork, after 14th Feb?
When are you planning to retest? 4-5 weeks after introducing the T4 you can test your TSH and TT4/FT4 values.
 
So after the last bloodwork, after 14th Feb?
When are you planning to retest? 4-5 weeks after introducing the T4 you can test your TSH and TT4/FT4 values.
oh woops. it didnt show the date. I introduced it in 1/25 or 1/26

1648246394853.png
 
oh woops. it didnt show the date. I introduced it in 1/25 or 1/26

View attachment 162367
Oh ok, that is what I wanted you to confirm lol.

3 weeks is probably is the limit to start getting real info when introducing the T4, but it seems your free T4 is over the limit, do you have the right total T3 values for the last bloodwork?
Total T4 is even lower but I noticed you also increased the HGH to 7 IU from 4 IU, so you might needed some extra weeks.
Are you retesting soon? After 5-6 weeks from your last bloodwork is enough time to see what your thyroid looks after increasing the HGH.
 
Exogenous T4 is not necessary with rhGH unless one has pre-existing central hypothyroidism (rhGH can reveal central hypothyroidism, but not cause it). The decrement in serum T4 (within physiological ranges) is due to increased peripheral conversion of T4 to T3 (responsible for some but not all of rhGH's increase to RMR).
but isn't it better to use T4 so you get more conversion from T4 to T3 which releases D1 &D2 and lowers D3 which reduces body fat burning?
 
but isn't it better to use T4 so you get more conversion from T4 to T3 which releases D1 &D2 and lowers D3 which reduces body fat burning?
I've commented on the 2006 Anthony Roberts article before making these claims based on rodent data (note that rat GH is a different compound altogether from 22-K hGH).

The crux of that article is that:
GH is HIGHLY synergistic with T3 in the body, and as a mater of fact, if you’ve been paying any attention up until this point, you’ll note that the limiting factor on GH’s ability to exert many of it’s effects, is mediated by the amount of T3 in the body.

As noted before, T3 enhances many effects of GH by several mechanisms, including (but not limited to): increasing IGF-1 levels, IGF-1 mRNA levels, and finally by actually mediating the control of the growth hormone gene transcription process as seen below:

Comparison of the kinetics of L-T3-receptor binding abundance to changes in the rate of transcription of the GH gene.(3)

As you can see, T3 levels are directly correlative to GH gene transcription. The scientists who conducted the study which provided the graph above concluded that the amount of T3 present is a regulatory factor on how much GH gene transcription actually occurs. And gene transcription is what actually gives us the effects from GH. This last fact really seems to shed some light on why we need T3 levels to be supraphysiological if we’re going to be using supraphysiological levels of GH, right?
There's rodent data that intramuscular IGF-I is related to replacement doses of rat GH+T3 (remember different GH molecule) in rats whose thyroid was removed. There's some statistical evidence suggesting similarilities in gene transcription between rat GH & T3 binding... This is such tangential, unrelated minutae to supraphysiological rhGH use that it's baffling. I have not seen evidence of tethering between thyroid function & growth hormone function in human genomic work.

Frankly, I don't really know what AR was thinking. But this was never supported in human data & is a wild outlier (it's bro science with a very convoluted pseudoscientific spin). This article is the only source that has ever existed that makes these claims regarding hGH. They have not withstood the test of time well (except being raised as support for the notion that T4+rhGH is a good idea on bodybuilding forums).

T3 increases with exogenous rhGH administration due to peripheral conversion of T4 to T3. Great. The increase in T3 contributes about 50% to GH's increase in REE. GH's primary lipolytic mechanisms have nothing to do with REE nor thyroid. That alone should tell you the unbelievable irrelevance of this 2006 article today.

If you want to keep taking T4 with your rhGH, by all means! It's just unnecessary.
 
I've commented on the 2006 Anthony Roberts article before making these claims based on rodent data (note that rat GH is a different compound altogether from 22-K hGH).

The crux of that article is that:

There's rodent data that intramuscular IGF-I is related to replacement doses of rat GH+T3 (remember different GH molecule) in rats whose thyroid was removed. There's some statistical evidence suggesting similarilities in gene transcription between rat GH & T3 binding... This is such tangential, unrelated minutae to supraphysiological rhGH use that it's baffling. I have not seen evidence of tethering between thyroid function & growth hormone function in human genomic work.

Frankly, I don't really know what AR was thinking. But this was never supported in human data & is a wild outlier (it's bro science with a very convoluted pseudoscientific spin). This article is the only source that has ever existed that makes these claims regarding hGH. They have not withstood the test of time well (except being raised as support for the notion that T4+rhGH is a good idea on bodybuilding forums).

T3 increases with exogenous rhGH administration due to peripheral conversion of T4 to T3. Great. The increase in T3 contributes about 50% to GH's increase in REE. GH's primary lipolytic mechanisms have nothing to do with REE nor thyroid. That alone should tell you the unbelievable irrelevance of this 2006 article today.

If you want to keep taking T4 with your rhGH, by all means! It's just unnecessary.
Thanks. I'll stop it to see how I feel. I don't know if I feel any different than the start. I'll continue my regimen until Monday. Grab some lab work. Stop the t4 and see how I feel on out.
Monday is lab work day
 
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