Janoshik Analytical laboratory testing services

[Sampei]

I don't have any dog in this fight but this was just a few months ago .Actually Jano results came in even higher than Analizia t

It's one year ago almost lol

 

[Lovegod82]

Hahaha I knew you was going to say that .But facts are fact with this test results..For the most part you can find the test results in his web page for the current batches.

 

[MyNameIsJeff]

I don't have any dog in this fight but this was just a few months ago .Actually Jano results came in even higher than Analizia t

Wait, so even with Janoshik's new testing method, TP's Black Tops have 98% purity and no dimer content? That's better than the competition, no?

 

[bigboy420]

Are 3 tests any cheaper? And bundles here?

 

[Lovegod82]

Wait, so even with Janoshik's new testing method, TP's Black Tops have 98% purity and no dimer content? That's better than the competition, no?

That is correct Jeff, now that was for batch 126. According to both test done on this batch by different facility I don't have any reason to doubt that any of his stuff has been tested by Analiza bialek are faulty. Yes better than any any competitors as of late.

 

[MyNameIsJeff]

That is correct Jeff, now that was for batch 126. According to both test done on this batch by different facility I don't have any reason to doubt that any of his stuff has been tested by Analiza bialek are faulty. Yes better than any any competitors as of late.

A surprise, but a welcome one. Do you know who published this test? In any case, thanks for sharing it.

 

[Lovegod82]

No problem man .Here is the link

Thread 'TP HGH Black Tops Janoshik Test results' TP HGH Black Tops Janoshik Test results

 

[RintintinRedRocket]

How long does it take for Jano to send shipping instructions after notice of payment? I requested a test and within a few minutes I received an email for payment. Made payment, notified Jano but still waiting for shipping instructions. Has only been a day but thought it would be right away after the prompt response to the testing request.

 

[SpicyMeatball]

How long does it take for Jano to send shipping instructions after notice of payment? I requested a test and within a few minutes I received an email for payment. Made payment, notified Jano but still waiting for shipping instructions. Has only been a day but thought it would be right away after the prompt response to the shipping request.

Wait 7 days then ask for a tracking number.

 

[janoshik]

How long does it take for Jano to send shipping instructions after notice of payment? I requested a test and within a few minutes I received an email for payment. Made payment, notified Jano but still waiting for shipping instructions. Has only been a day but thought it would be right away after the prompt response to the testing request.

It's Saturday, my email team doesn't work weekends. Possible you've mailed us at the end on their Friday shift.

 

[janoshik]

I checked and the team forgot to turn on the weekend autoreply informing clients about the fact we don't reply on the weekends - my apologies about that.

 

[RintintinRedRocket]

It's Saturday, my email team doesn't work weekends. Possible you've mailed us at the end on their Friday shift.

Thank you for the response

 

[Ghoul]

@janoshik

-Have you ever been asked to measure dimer in a peptide other than HGH? I was looking for a peptide analysis result with dimer, other than HGH, but couldn't find one.

-Do aggregates larger than dimer (oligimers through visible >100um) get included in the dimer measurement, or do aggregates larger than dimer subtract from purity?

-Are samples filtered post reconstitution, prior to, what I assume(forgive me if this is wrong) is Size Exclusion Chromatography for dimer measurement?

Thanks in advance!

 

[janoshik]

@janoshik

-Have you ever been asked to measure dimer in a peptide other than HGH? I was looking for a peptide analysis result with dimer, other than HGH, but couldn't find one.

no

@janoshik


-Do aggregates larger than dimer (oligimers through visible >100um) get included in the dimer measurement,

yes, but I scratched what I don't really understand/doesn't make sense

-Are samples filtered post reconstitution, prior to, what I assume(forgive me if this is wrong) is Size Exclusion Chromatography for dimer measurement?

only those that exhibit anything worrying such as turbidity etc


cheers

 

[Ghoul]

no


yes, but I scratched what I don't really understand/doesn't make sense



only those that exhibit anything worrying such as turbidity etc


cheers

Thanks for the answers. I ask, in my clumsy layman's way, because I've been reading about the increasing focus of pharma manufacturers on aggregates, particularly in the context of immunogenicity developing, making peptide based therapies less effective, and in some cases causing side effects of varying degrees.

Larger aggregates appear to develop well after manufacture, as a result of packaging (the presence of silicone in auto injectors for instance) and handling (poor temperature control and shear stresses from significant agitation).

The studies looking into this either used "aged" retail, non-lypholized peptides or simulate the conditions described, allowing times of 5+ days to "incubate" for these larger aggregates to develop. So a lot of the effort to prevent aggregation has been on packaging.

Here's an illustration regarding the size classification of aggregates I was referring to:






Thanks again for indulging me, you are a unique, irreplaceable asset to this community.

 

[Ghoul]

For completeness and context, here's an example of "abused" GLP-1 forming large, therapeutically inactive aggregates.

https://royalsocietypublishing.org/doi/10.1098/rsfs.2017.0030

 

[SpicyMeatball]

Wait 7 days then ask for a tracking number.

Sorry I thought I was in the qsc thread when i said this, please ignore it. Jano’s service level is different.