New member here, first post.
About a month ago, I began using it solo in lieu of TRT. It has advantages over testosterone - basically for a dose similarly androgenic to test, it is about 3x as anabolic. It converts via multiple pathways into estrogen, via aromatase as well as through an estrone intermediary, but is not subject to 5a-reductase so cannot convert to DHT. It also does not raise hematocrit and is more selective than test, at least at lower dosages, so is less likely to cause hair loss and BPH. It's also an ideal compound to 'blast and cruise' on... cruise <5mg/day, increasing up to 50mg/day for a blast.
The 7a-methylestradiol activates ER similarly to regular estradiol, but it is eliminated from the body more slowly so can accumulate resulting in estrogenic effects. So AI and/or SERM can be useful - particularly at higher dosages, in those also using test, or those with genetically high aromatase activity. It also activates progesterone receptors and therefore should be expected to increase prolactin in a dose-dependent manner; at all but high dosages, this is probably insignificant although I am taking Inhibit-P/P5P; at very high dosages, something stronger i.e. cabergoline or praxiprexole might be needed for some.
I'm currently injecting 20mg/day subQ (completely painless) in divided doses for a mini-blast. My adjuncts are Raloxifene 30mg/day for gyno prophylaxis, since 7a-methylestradiol cannot be measured via blood, and Aromasin 12.5mg EOD. I have neither excess water retention or elevation of BP, nor have I had any low E2 symptoms. My joints feel great and libido is improving. Over the past few weeks I have noticed a significant increase in muscle mass (+1 inch on my arms) and strength, with my weight remaining stable @ 200lbs... so it is working well, as intended, for body recomposition purposes.
Btw I'm a 54 year old physician (MD/radiologist) and have done extensive research on this compound.