IGF, in my experience(which is quite significant) can be a finicky thing. In my experience in a perfect world, someone who converts as expected will get 100iu points per IU of injected GH. However, some people, for whatever reason, just don't convert well. I have seen this in people who were running pretty heavy cycles including hepatoxic compounds(orals, tren, etc) many times deep into a prep, etc, and I have seen it in guys running NOTHING. I have seen guys who had pulled these shitty numbers, come off these heavy cycles, and IGF comes back up, and on the other hand, I have seen people who just never convert well.
This is why I maintain that IGF isn't a great test for GH verification. It relies on conversion. It is not a "if you take this, this WILL happen" scenario. It would be like trying to quantify if testosterone is real, or how it is dosed, by using estrogen levels. Well shit, some peoples E2 levels don't rise much. It can be a good test if we have a known good responder, or for ones on peace of mind, but at the end of the day, the fact is, I have seen people who are known good responders go through bouts of lower IGF. And it isn't always as simple as going "or you are running tren" or an oral, or whatever.
I will give you an example, myself. No matter what I take, I can not get my IGF-1 over 200. I have yet to figure out why. This is off everything, on nothing more than a TRT dose of test, no signs of insulin resistance, etc. This goes back YEARS, and on all pharma GH(huma,nordi, geno, sero, doesn't matter). 10iu? Doesn't matter.
On the flip side, the positive effects of GH are undeniable. So I don't really even know what to make of it anymore. I will say, naturally, my liver enzymes, and billirubin, are on the higher side of normal. I am wondering if I have some sort of condition that prevents proper conversion to IGF. I have played around with so many variables over the years, but just never been able to isolate it. So all I can do is chalk it up to, that is my body.
S-