Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic

I jumped from 3mg (5mg watered down by a compounding pharma) to 7.5mg from QSC about 3 months into my GLP regimen. I got violently ill. Violently violently ill for a full day. Projectile Vomiting, water shits, pancreas attack. I was fine eventually, but I absolutley did not vomit because I 'overate'. I vomited because I overdosed.
My understanding is that GLP-1 interacts with the stretch sensors in your stomach. Just like your muscles have sensors that detect that they are being stretched too far. Your natural defense to keeping from damaging your stomach is to empty it. While you might not have actually over eaten, your brain thought that you did.
 
I was really about to stir the pot and say that 300 lbs of solid muscle is harder on the heart than being 300 lbs of a fat body.

That wouldn’t stir the pot. Doesn’t take a rocket scientist to know the 300lb fatty has arteries pathways the diameter of their 29g needles they pin their semaglutide with.
 
That wouldn’t stir the pot. Doesn’t take a rocket scientist to know the 300lb fatty has arteries pathways the diameter of their 29g needles they pin their semaglutide with.
But if your max heart rate is your resting heart rate at 110 bpm, you don’t need clean duct work. On the other hand having to feed nutrients and oxygen to 300 lbs of sex appeal through those same small arteries because of AAS abuse is taxing.
 
I jumped from 3mg (5mg watered down by a compounding pharma) to 7.5mg from QSC about 3 months into my GLP regimen. I got violently ill. Violently violently ill for a full day. Projectile Vomiting, water shits, pancreas attack. I was fine eventually, but I absolutley did not vomit because I 'overate'. I vomited because I overdosed.

Of which drug?
 
All this discussion about GLP drugs, yet no one talks about how, even on GLP drugs, people still need to want to lose weight. There's countless cases of people who do bariatric surgery and still get fat. It doesn't matter what you do, what drugs you take, if you don't want to actually lose weight, you won't.

I'm on them, I started taking them for both the insuline sensitivity benefits, as well as the appetite suppression. I still lift 6 times a week and track every single calorie I eat, having done so for more than a year now. I'm down over 70kg. If taking GLP drugs means I'm a lazy piece of shit, so be it, at least I'm getting results, forming better habits and getting healthier.
 
But if your max heart rate is your resting heart rate at 110 bpm, you don’t need clean duct work. On the other hand having to feed nutrients and oxygen to 300 lbs of sex appeal through those same small arteries because of AAS abuse is taxing.

Okay now you’re trying to stir the pot lol.

“Fat people don’t excercise so they don’t need a healthy heart”
- @LGOP528

Pure genius. The next type II
 
All this discussion about GLP drugs, yet no one talks about how, even on GLP drugs, people still need to want to lose weight. There's countless cases of people who do bariatric surgery and still get fat. It doesn't matter what you do, what drugs you take, if you don't want to actually lose weight, you won't.

I'm on them, I started taking them for both the insuline sensitivity benefits, as well as the appetite suppression. I still lift 6 times a week and track every single calorie I eat, having done so for more than a year now. I'm down over 70kg. If taking GLP drugs means I'm a lazy piece of shit, so be it, at least I'm getting results, forming better habits and getting healthier.
I don’t think anyone is against using glp1s to lose weight, same thing as people here shouldn’t be judging gear heads of steroid use in a forum dedicated to bodybuilding.

However , just like how sane members remind other members to keep their dosages in mild, have blood work done regularly and not perma blast; it is also advised to use these drugs as tools and learn how to keep the weight off when you take a break when you stop responding to these glp1 drugs.

Just like how they discourage newbies to jump on cycle without dialing their eating habits and lifting lifestyle, they encourage you to at least learn a way to keep the fat off even without the drugs.

Btw, good job on the fat loss, this place might look like everyone is on each other’s neck but reality we are rooting for each other and just display our passion in a weird manner lol.
 
All this discussion about GLP drugs, yet no one talks about how, even on GLP drugs, people still need to want to lose weight. There's countless cases of people who do bariatric surgery and still get fat. It doesn't matter what you do, what drugs you take, if you don't want to actually lose weight, you won't.

I'm on them, I started taking them for both the insuline sensitivity benefits, as well as the appetite suppression. I still lift 6 times a week and track every single calorie I eat, having done so for more than a year now. I'm down over 70kg. If taking GLP drugs means I'm a lazy piece of shit, so be it, at least I'm getting results, forming better habits and getting healthier.

I do agree somewhat. I have friends who are not diciplined about their GLP's, and are not diciplined about losing weight, and they suffer.

But GLP's prevent backsliding when your diet fucks up unlike any other procedure, including a gastric bypass. Work stress had me give up on weight loss for about 2-3 months. I know even gastric bypass people who have gotten totally derailed. Without GLP's I would've gained 15lbs easily. With GLP's I gained only 5lbs and I'm back on track, lost it in only 10 days.

Point being, the physiological changes that are provided by a GLP are massive and show that being obese is a true medical condition IMO. But yes if you do not choose to lose weight and focus on it you can't expect results.


Of which drug?
Tirz obviously. Get it together.
 
All this discussion about GLP drugs, yet no one talks about how, even on GLP drugs, people still need to want to lose weight. There's countless cases of people who do bariatric surgery and still get fat. It doesn't matter what you do, what drugs you take, if you don't want to actually lose weight, you won't.

I'm on them, I started taking them for both the insuline sensitivity benefits, as well as the appetite suppression. I still lift 6 times a week and track every single calorie I eat, having done so for more than a year now. I'm down over 70kg. If taking GLP drugs means I'm a lazy piece of shit, so be it, at least I'm getting results, forming better habits and getting healthier.

The fact so many people decided sticking a needle into themselves was acceptable, which is a huge hurdle because most find that idea terrifying, showed the willingness to do anything to lose weight. I have a feeling that once getting over that barrier, a lot of guys decided TRT was ok too.
 
Honestly guys, whether you’re team Roids or team GLP- give it 2 months and you’ll be balls deep.

I found this forum back before or at least the genesis of GLPs, hoping to find a cheaper source for BPC & other peptides I was spending too much on with peptidesciences.

Maybe a month or two later I was on Test, Primo & HGH. 8 months later I ran Tren.

So, give it time. You stick around this forum the bug will bite you. You’ll stare at that price list and justify to yourself “man I can get a lifetime of testosterone for $200”

Then next thing you know you’re on Tren A, 8% BF with frikken abdominal veins and your girlfriend is hurting from the intensity of your libido now.
 
I do agree somewhat. I have friends who are not diciplined about their GLP's, and are not diciplined about losing weight, and they suffer.

But GLP's prevent backsliding when your diet fucks up unlike any other procedure, including a gastric bypass. Work stress had me give up on weight loss for about 2-3 months. I know even gastric bypass people who have gotten totally derailed. Without GLP's I would've gained 15lbs easily. With GLP's I gained only 5lbs and I'm back on track, lost it in only 10 days.

Point being, the physiological changes that are provided by a GLP are massive and show that being obese is a true medical condition IMO. But yes if you do not choose to lose weight and focus on it you can't expect results.



Tirz obviously. Get it together.

LOL, I'm not the one who OD'd (have in the past though) so I'm not gonna to assume anything,

Here's what I've experienced first hand and seen in others.

You know a signature effect of these drugs is eating increasingly smaller portions.

Force yourself to eat too large a portion for the dose (beyond your appetite) and throwing up is a common reaction. (often preceded by incessant hiccups for some reason). I'm not saying that's what you did.

The physical adverse reaction to too large a portion kicks in before the appetite reduction effects for that dose do.

So while you can be eating what's fine for 3mg, take a much higher dose, and if that 3mg acceptable quantity of food's still in your gut, you'll get as sick as if you ate it after you felt the 7.5mg appetite reduction and ate beyond that. Truthfully the next normal titration level will make you feel a bit ill for the same reason, but the big jump makes the differential higher and intensity of "punishment" much worse.

To make matters worse, a lot of UGL glps are overdosed by 20%-25%.

So while I advocate for a faster titration, 2 weeks per level if sides are tolerable, never skip a level, never take a "top up" midweek because you're not feeling it.

Kudos to you for not quitting after that. You do eventually reach stasis with no side effects whatsoever.
 
I'm still not clear on GLP1s main method that induces weight loss. Is it blunting of hunger, or through some sort of extra-metabolic work that bypasses traditional caloric balance like DNP's uncoupling? If it's both, which weighs heavier for results?

This is NOT to infer that taking GLP1 makes one lazy. I'm just curious as to what primarily causes the weight-loss.
 
I'm still not clear on GLP1s main method that induces weight loss. Is it blunting of hunger, or through some sort of extra-metabolic work that bypasses traditional caloric balance like DNP's uncoupling? If it's both, which weighs heavier for results?

This is NOT to infer that taking GLP1 makes one lazy. I'm just curious as to what primarily causes the weight-loss.

They make you such a whiny biotch that all the crying and typing burns an extra 500 calories a day
 
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