temptation and striving for more.... but health should be the main goal in life

[newbie23]

I do get sick more on TRT and it bugs me. I dont know why this is.

estrogen maybe?

To make this discovery, Gronert and colleagues administered a mild abrasion injury to the front of the eye of genetically similar male and female mice, and analyzed wound healing by image analysis. To test the role of estrogen, they gave male mice estrogen eye drops and/or drugs that activate specific estrogen receptors. Gene expression of essential enzymes was quantified for the formation of protective lipid signals, specific receptors that mediate their bioactivity, as well as estrogen receptors in mouse corneas and human/mouse epithelial cell cultures. The formation of protective lipid signals was analyzed by a mass-spectrometry based lipidomic method. They found that estrogen negatively affects a highly evolved protective lipid circuit, called "15-lipoxygenase-Lipoxin A4" that has recently emerged as an important protective pathway in many diseases. This pathway balances the activity of pro-inflammatory signals to promote wound healing and to keep inflammation within safe ranges.

Estrogen is responsible for slow wound healing in women, study finds

I know this is a study on mice and wound healing, but most sickness comes from some sort of inflammation. This I am sure is what attributes to cystic acne in men on TRT and why sometimes an AI will help to alleviate some of it.

 

[foreveryoung]

who knows, it seems like it's more an immune system that is confused, like it isn't sure whether to get sick or not all the time, any time someone sniffles or sneezes anywhere near you you almost get a feeling like you are going to be sick again

 

[newbie23]

who knows, it seems like it's more an immune system that is confused, like it isn't sure whether to get sick or not all the time, any time someone sniffles or sneezes anywhere near you you almost get a feeling like you are going to be sick again

I agree on immune system, estrogen plays a role in its response.

 

[foreveryoung]

I agree on immune system, estrogen plays a role in its response.

could be estrogen or a number of other hormones that are affected and which levels are rising and falling at unnatural times compared to a purely natural pulsatile system. I don't think science will have this figured out for a long long time unfortunately, but the reality is that it is what it is

 

[foreveryoung]

just did a second cyp injection, was going to wait until tomorrow, but thought it over and in the spirit of frontloading and trying to get levels to overlap and stabilize out the valleys I did it today

all this talk in the thread about sickness has got me a bit paranoid hypochondriac and thinking I feel a scratchy throat, really hope it's just in my head because I can't afford to get sick right now (some people around town I have heard sneezing so it gets you thinking on the subject)

mood today was a little bit on the grouchy side, nothing like tren but I was not as easy going as I usually am about things today

workout recovery was good, exercised hard and feel the urge to go for more

libido shows no real urge increase when not directly involved in the act, maybe just a little tiny bit more of an urge, but unsure

 

[1erCru]

Are you trying to convince everybody else TRT is a failed concept or are you trying to convince yourself?

 

[foreveryoung]

Are you trying to convince everybody else TRT is a failed concept or are you trying to convince yourself?

not trying to convince anyone anything, just relating my experiences and theories. I was asked specific questions about a statement I made while describing my situation earlier in the thread.

the thread itself is more an all-containing journal of my path hormonally and the day to day thoughts and experiences as I go through them, for my own benefit and also for anyone else that might find it interesting or of value to read as I detail my experiments and experiences

 

[foreveryoung]

libido has definitely dropped late this evening, maybe the arimidex, not sure, feel ok though, just pretty flaccid and uninterested in getting erect for anything, in noticeable contrast to other recent evenings

testicle size still seems normal, will try to keep on top of noticing any changes

not sure if I will take another proviron tonight, I'm thinking it might be an idea to "bridge" with those until the testosterone levels start to level out with the benefit of a few shots

shoulder is still very achy sore



*disclaimer: all of my posts and descriptions on this website are not to be taken as any advice or taken as based on any reality, and are posted as fantasy roleplay only

 

[foreveryoung]

libido better, a bit of spontaneous libido this evening

took a 25mg proviron today

 

[foreveryoung]

knees and elbows seem a little achy, I wonder if the arimidex might not have been a good idea at this point, feel a little too fatigued too

 

[foreveryoung]

strong wood this morning

little stuffy nose and scratchy throat, please go away any sickness..some dude that was sneezing was at the next table while I was eating lunch yesterday...hate when that happens


skin still ok, thought maybe my face felt a tiny bit oilier than usual, I think I might go tanning today

 

[foreveryoung]

feel good this afternoon, no cold or anything
500mg cyp so far and so far so good, not sure about continuing the proviron but took 25mg this morning

 

[foreveryoung]

already noticing an improvement in muscle flexibility,not sure if its the test or the proviron, or both. in the past I noticed this same thing quite rapidly with masteron, but I think low normal test seems to cause less flexibility with me that is remedied with test or androgens

 

[foreveryoung]

strong libido this evening

 

[foreveryoung]

well on the libido subject, I definitely notice an increase in my finding more girls more attractive, some not as attractive girls that I see often have me thinking sexual thoughts about them today, so that is a sign that my brain is getting more desire, but it hasn't really translated at all to a blood flow in the penis, nothing like in younger days where a stroke or two was enough to get an erection, or random hot girls throughout the day used to cause the beginnings of involuntary erections

my function is good when I do get into it with visual and manual stimulation at the same time, so that is good.... still hoping for more, recapturing the extreme libido of my youth is still elusive and still something I am searching for

 

[foreveryoung]

testicle shrinkage finally noticeable today

concerned about some lack of function this evening too, was able to orgasm and ejaculate but my penis stayed somewhat soft throughout

I don't "feel" what I would think is high estrogen, but not sure, I haven't taken any arimidex for awhile, and felt lousy after the last time, which may not be related

 

[foreveryoung]

just took 1/2 mg arimidex

 

[foreveryoung]

just woke up, zero morning wood, limp, didn't expect this already, a little concerned

 

[foreveryoung]

hmm, 20 minutes later lying down here with the laptop checking around some sites and all of the sudden strong wood, strange, I was questioning my decision to go back on strongly and playing out in my mind whether quitting and the possible stresses of recovery already, but then this wood came on strong, confusing.... all a guy wants is reliability....

 

[foreveryoung]

feel pretty good this afternoon

balls are small