Wife needs a boost pt141 vs oxtocin?

[narta]

I am seriously being pushed to finalise having a lobotomy, stop being a retard and start auditioning for victims, aka volunteers, for my PT141 initiation.

LOL

 

[readalot]

Any feedback on pt-141 potential effect on prolactin release after orgasm? Still aroused or same typical moment of clarity / disgust?

 

[narta]

Any feedback on pt-141 potential effect on prolactin release after orgasm? Still aroused or same typical moment of clarity / disgust?

The refractory period is significantly shorten. Not caber recovery, but better than nothing.

What I don't understand is the clarity/disgust. I never felt disgusted after the deed. Less horny yes, but disgusted? (even with the kinks I have)

 

[readalot]

The refractory period is significantly shorten. Not caber recovery, but better than nothing.

What I don't understand is the clarity/disgust. I never felt disgusted after the deed. Less horny yes, but disgusted? (even with the kinks I have)

Just trying to "cover a broad cross section of potential readers" lol.
Thanks for the feedback. Glad your kinks aren't too bad.

 

[Grey Spartan]

(even with the kinks I have)

If you post a picture with nipple clamps, @iris is going to blow a gasket.

 

[narta]

If you post a picture with nipple clamps, @iris is going to blow a gasket.

Nah, that's for the really kinky ones, I am much more reserved. Just "plain" maledom stuff.

As for @iris she is probably has a spreadsheet inputting Limeys/candidates as we speak

 

[cmK9s33]

That's a significant dose to illicit such little effect and low sides. MT2 I great so defiantly try that, but I wonder if your PT is good. Maybe try 3.5. That's my usual dose.

Well damn. You were definitely right about threshold dose. As mentioned, 3mg provided little effect. Tried 3.67mg (0.55 ml of a 1.5ml solution) and yep that did the trick. Felt the “nausea” just afterwards for about 10-15 minutes and then nothing. I mean absolutely nothing and thought “I guess I really am a non-responder.” Then about 6 hours later, it finally took effect.
Didn’t quite send my libido into the stratosphere, but it definitely elicited a very positive and noticeable effect on libido and overall sensation. Thank you for the advice.

 

[sushak]

Well damn. You were definitely right about threshold dose. As mentioned, 3mg provided little effect. Tried 3.67mg (0.55 ml of a 1.5ml solution) and yep that did the trick. Felt the “nausea” just afterwards for about 10-15 minutes and then nothing. I mean absolutely nothing and thought “I guess I really am a non-responder.” Then about 6 hours later, it finally took effect.
Didn’t quite send my libido into the stratosphere, but it definitely elicited a very positive and noticeable effect on libido and overall sensation. Thank you for the advice.

I've felt like shit all day after dosing 2.5mg last night, flu like, lethargic aching joints and a bit depressed. 2nd time this has happened after pt141. Didn't even get any ass either last night

 

[narta]

I've felt like shit all day after dosing 2.5mg last night, flu like, lethargic aching joints and a bit depressed. 2nd time this has happened after pt141. Didn't even get any ass either last night

depression is most likely from not getting any ass

 

[Ghoul]

I've felt like shit all day after dosing 2.5mg last night, flu like, lethargic aching joints and a bit depressed. 2nd time this has happened after pt141. Didn't even get any ass either last night

Filter it and try one last time. You're describing the effects of a cytokine storm, an immune response. Or you may want to wait, as your immune system may already sensitized, antibodies present, and react to even unaggregated PT-141 and react the same way.

 

[Ghoul]

Here's the report I referred to earlier and a detailed post on protein aggregation I dropped in Mesa's cesspool thread:

Aggregation of protein therapeutics enhances their immunogenicity: causes and mitigation strategies

Protein aggregation in biotherapeutics has been identified to increase immunogenicity, leading to immune-mediated adverse effects, such as severe allergic responses including anaphylaxis. The induction of anti-drug antibodies (ADAs) moreover enhances drug clearance rates, and can directly block...

pubs.rsc.org

Post in thread 'Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic'

Sep 28, 2024

I appreciate the thorough response! Bought some sterile vials and syringe filters. Is it a good idea to filter most of the peptides into new vials or is it just a big thing with Tesamorelin? Thanks!

I'm filtering all my peptides now, based on what I've learned. This is an increasing concern with commercial pharma producers as peptides become more widespread therapeutics. Most of the aggregation appears to happen in the final product container once it's in the hands of the user.

I ended up going down this rabbit hole for a few reasons, and a "cloudy" batch of PIP inducing Tesa...

• Ghoul

• 
• 

 

[sushak]

Filter it and try one last time. You're describing the effects of a cytokine storm, an immune response. Or you may want to wait, as your immune system may already sensitized, antibodies present, and react to even unaggregated PT-141 and react the same way.

It is plausible, and this vial has been reconstituted for ages tbh, probably 3 month. Lazy and irresponsible of me, especially given how cheap it is. Will chuck it and try again with a new vial and use a filter in the name of science! But not this weekend lol

 

[Ghoul]

It is plausible, and this vial has been reconstituted for ages tbh, probably 3 month. Lazy and irresponsible of me, especially given how cheap it is. Will chuck it and try again with a new vial and use a filter in the name of science! But not this weekend lol

For whatever reason, I've had more issues with cheap PT than other peptides. Not lately, but a few years ago there was a big difference between the no name stuff and Peptide Sciences, which cost a fortune. They be all been fine in recent years though. Maybe it's just more unstable than others.

 

[iris]

Nah, that's for the really kinky ones, I am much more reserved. Just "plain" maledom stuff.

As for @iris she is probably has a spreadsheet inputting Limeys/candidates as we speak

Not yet. I am currently spending the day arguing with my mother, so no spreadsheet available, but you can get one ready for me, if you deem it necessary.

What is maledom?
Like, Marquis de Sade stuff?

 

[narta]

you can get one ready for me, if you deem it necessary.

I ain't touching that

Mama didn't raise no dummy.

Google the other thing lol

 

[iris]

If you post a picture with nipple clamps, @iris is going to blow a gasket.

Yes, reactionary nun-like, right here.

I was thinking that I really have to keep in mind the initial nausea/projectile vomiting phase and make sure it's fully completed, otherwise instead of a great shag the only thing I will get is his dry cleaning bill, lol.

Good job Ghoul is here with comprehensive instructions, because left to my own devices something like that would be on the cards.

Those clamps sound nasty....
Ouch. U like that?

 

[iris]

I ain't touching that

Mama didn't raise no dummy.

OK, pen and paper it is

 

[iris]

For whatever reason, I've had more issues with cheap PT than other peptides. Not lately, but a few years ago there was a big difference between the no name stuff and Peptide Sciences, which cost a fortune. They be all been fine in recent years though. Maybe it's just more unstable than others.

Where are you getting it from?
Yeah, OK, no sources discussion, etc.
But is it Tracy's?
Lol

Is it as vintage as the tesa?
I want some

 

[narta]

OK, pen and paper it is

Still no. Even if it was in inscriptions like I am used to.

 

[iris]

Still no. Even if it was in inscriptions like I am used to.

Oh no, I meant I will use pen and paper, not you.
I wouldn't ask you to be my PA for this project, you got better things to do Marquis de Sade style.
I got nothing on that.