Fat Loss via other mechinisms

[MFAAS]

Can you post links to the studies you’ve read? The 4 studies I’ve read in support of albuterol use were pretty disappointing.

It is never gonna be a impressive as clen. But the fact that it has the effects it has with essentially zero sides for most people is why alot of people like it, including myself.

So I looked again and there's really not much impressive research around salbutamol for fat loss. In my experience, anecdotally, it has significantly helped my cuts before, but it certainly is no clen. I've never done clen either so yeah. There are a few studies that show salbutamol to have fairly impressive activity on hypertrophy and muscle mass. So perhaps in a cut it is simply surpassing appetite and possibly helping to maintain muscle to some degree, especiallywhen paired with anabolics. I don't have a solid answer. anyway, links below.

Hypertrophy/power output/strength:

Effect of salbutamol on innervated and denervated rat soleus muscle - PubMed

The objective of the present investigation was to perform a 14-day time-course study of treatment with salbutamol, a beta2 adrenoceptor agonist, on rat soleus muscle in order to assess fiber type selectivity in the hypertrophic response and fiber type composition. Male Wistar rats were divided...

pubmed.ncbi.nlm.nih.gov

Beta2 -adrenoceptor agonist salbutamol increases protein turnover rates and alters signalling in skeletal muscle after resistance exercise in young men - PubMed

The effect of beta₂ -adrenoceptor stimulation on skeletal muscle protein turnover and intracellular signalling is insufficiently explored in humans, particularly in association with exercise. In a randomized, placebo-controlled, cross-over study investigating 12 trained men, the...

pubmed.ncbi.nlm.nih.gov

β2-Adrenergic agonist salbutamol augments hypertrophy in MHCIIa fibers and sprint mean power output but not muscle force during 11 weeks of resistance training in young men - PubMed

In this study, we examined the effect of β₂-agonist salbutamol at oral doses during a period of resistance training on sprint performance, quadriceps contractile function, skeletal muscle hypertrophy, fiber type composition, maximal activity of enzymes of importance for anaerobic...

pubmed.ncbi.nlm.nih.gov

Metabolism and fat loss:

The effect of caffeine and albuterol on body composition and metabolic rate - PubMed

In rats, albuterol with caffeine produced significantly greater increases in lean body mass and reductions in fat mass without changes in food intake after 4-8 weeks of treatment. Since caffeine and albuterol are approved for the treatment of asthma in children and adolescents at the doses...

pubmed.ncbi.nlm.nih.gov

 

[Euricomiranda]

Can you post links to the studies you’ve read? The 4 studies I’ve read in support of albuterol use were pretty disappointing.

Was it disappointing compared to ephedrine?

 

[cmK9s33]

Was it disappointing compared to ephedrine?

I’ve never read any studies on ephedrine nor have I tried searching for any. And what praytell would you be implying with the question?

 

[cmK9s33]

It is never gonna be a impressive as clen. But the fact that it has the effects it has with essentially zero sides for most people is why alot of people like it, including myself.

So I looked again and there's really not much impressive research around salbutamol for fat loss. In my experience, anecdotally, it has significantly helped my cuts before, but it certainly is no clen. I've never done clen either so yeah. There are a few studies that show salbutamol to have fairly impressive activity on hypertrophy and muscle mass. So perhaps in a cut it is simply surpassing appetite and possibly helping to maintain muscle to some degree, especiallywhen paired with anabolics. I don't have a solid answer. anyway, links below.

Hypertrophy/power output/strength:

Effect of salbutamol on innervated and denervated rat soleus muscle - PubMed

The objective of the present investigation was to perform a 14-day time-course study of treatment with salbutamol, a beta2 adrenoceptor agonist, on rat soleus muscle in order to assess fiber type selectivity in the hypertrophic response and fiber type composition. Male Wistar rats were divided...

pubmed.ncbi.nlm.nih.gov

Beta2 -adrenoceptor agonist salbutamol increases protein turnover rates and alters signalling in skeletal muscle after resistance exercise in young men - PubMed

The effect of beta₂ -adrenoceptor stimulation on skeletal muscle protein turnover and intracellular signalling is insufficiently explored in humans, particularly in association with exercise. In a randomized, placebo-controlled, cross-over study investigating 12 trained men, the...

pubmed.ncbi.nlm.nih.gov

β2-Adrenergic agonist salbutamol augments hypertrophy in MHCIIa fibers and sprint mean power output but not muscle force during 11 weeks of resistance training in young men - PubMed

In this study, we examined the effect of β₂-agonist salbutamol at oral doses during a period of resistance training on sprint performance, quadriceps contractile function, skeletal muscle hypertrophy, fiber type composition, maximal activity of enzymes of importance for anaerobic...

pubmed.ncbi.nlm.nih.gov

Metabolism and fat loss:

The effect of caffeine and albuterol on body composition and metabolic rate - PubMed

In rats, albuterol with caffeine produced significantly greater increases in lean body mass and reductions in fat mass without changes in food intake after 4-8 weeks of treatment. Since caffeine and albuterol are approved for the treatment of asthma in children and adolescents at the doses...

pubmed.ncbi.nlm.nih.gov

Thank you mate. I’ll give them a read tomorrow.

 

[Type-IIx]

Isn’t that what Helios is? Some have claimed great success with it and claim you can target specific areas for fat loss with it.

Yes it is, and don't get me wrong, they are synergistic by acting at different receptors. What I don't like about it is both increase sympathetic drive, increasing risk or severity of hypertension.

 

[Type-IIx]

Thanks! I have always been super sensitive to stims.


He was still referring to salbutamol--so 6-8 mg per day. No sides.

I'm curious why you think Salbutamol is worthless? Just not strong enough? The research I've read was pretty good regarding both far loss and mass gaining.

I simply think clen is much more effective and has a very favorable risk-reward profile.

 

[Euricomiranda]

I’ve never read any studies on ephedrine nor have I tried searching for any. And what praytell would you be implying with the question?

comparing the two with fat burning, would salbutamol be more effective?

 

[Canknucklehead]

Everything effective has been mentioned already.

I will add that green tea is a great natural fat burner with a plethora of health benefits.

 

[Someguy22]

Following this thread. Yohimbe has always interested me, but apparently it can cause pretty awful anxiety, which has prevented me from trying it. Paradoxically though I think there is research showing dosing yohimbe before exposure to a fear inducing thing (exposure therapy for phobias) caused people to lose fear of it faster. It is a very interesting substance.

I tried yohimbe and hated the way it make me feel. Upon doing some reading Rauwolscine / alpha-yohimbe was recommended with similar or better efficiency. Most stims give me horrible insomnia and a crash later in the day, I find no crash with Rauwolscine and it doesn't effect my sleep.

You can order the stuff on amazon for like $15 so not a very expensive product to try.

 

[Canknucklehead]

Yohimbine hcl is what you want

 

[Type-IIx]

@MFAAS @jJjburton I like albuterol a bit more than I thought after reading a bit more on it. It is a real weakness how short its half life is, though. I prefer clen greatly, but definitely do not think albuterol is worthless. Would you guys be interested in my writing something up about clen with mention of other B2AR agonists?

 

[Canknucklehead]

@MFAAS @jJjburton I like albuterol a bit more than I thought after reading a bit more on it. It is a real weakness how short its half life is, though. I prefer clen greatly, but definitely do not think albuterol is worthless. Would you guys be interested in my writing something up about clen with mention of other B2AR agonists?

Yes please

 

[MFAAS]

@MFAAS @jJjburton I like albuterol a bit more than I thought after reading a bit more on it. It is a real weakness how short its half life is, though. I prefer clen greatly, but definitely do not think albuterol is worthless. Would you guys be interested in my writing something up about clen with mention of other B2AR agonists?

Absolutely!!

 

[Type-IIx]

@MFAAS @Canknucklehead new thread: Clenbuterol focus: Practical Research on Clen & Beta2- Adrenergic Compounds, Protocols

 

[GreenAmine]

@MFAAS @jJjburton I like albuterol a bit more than I thought after reading a bit more on it. It is a real weakness how short its half life is, though. I prefer clen greatly, but definitely do not think albuterol is worthless. Would you guys be interested in my writing something up about clen with mention of other B2AR agonists?

I really like albuterol, and one of its positives for me is the short half-life. It doesn't mess with my sleep after a few days of acclimation, which is the only reason I have not tried clen. I have read that it is brutal on sleep.

 

[Villain]

I really like albuterol, and one of its positives for me is the short half-life. It doesn't mess with my sleep after a few days of acclimation, which is the only reason I have not tried clen. I have read that it is brutal on sleep.

Clen is pretty harsh on the heart as well, isn’t it?

 

[VenomYo]

@Type-IIx do you know if multiple injections spots will make the compound reach a peak/saturation faster, since the ester is being cleaved and released from multiple injections site all at the same time, or not?

For instance if i inject Test into 3 different places Subq

 

[Type-IIx]

I really like albuterol, and one of its positives for me is the short half-life. It doesn't mess with my sleep after a few days of acclimation, which is the only reason I have not tried clen. I have read that it is brutal on sleep.

Yes, I respect that completely. We've had this exact conversation before.

 

[Type-IIx]

@Type-IIx do you know if multiple injections spots will make the compound reach a peak/saturation faster, since the ester is being cleaved and released from multiple injections site all at the same time, or not?

For instance if i inject Test into 3 different places Subq

Theoretically, yes, this makes sense.

 

[VenomYo]

Theoretically, yes, this makes sense.

Also lets say I inject a microdose of Test E, 10mg for instance, wont it deplete the compound way sooner and render the long ester obsolete, do smaller doses(microdoses) pretty much just act like an Ace/base ester?