how to make transdermal testosterone?

[hijoshiki]

99.9% ethanol only has a dissolving power of 166mg/ml.
So imagine how weak 95% ethanol is...

Compared to 580mg/ml for benzyl alcohol, two different leagues.
Even DMSO has more dissolving power than ethanol, so you'll only be diluting the solution.

How much BA do you think you're getting in one dose. Does it irritate the skin, does it cause side effects like headache?

 

[BigOldBastard]

99.9% ethanol only has a dissolving power of 166mg/ml.
So imagine how weak 95% ethanol is...

Compared to 580mg/ml for benzyl alcohol, two different leagues.
Even DMSO has more dissolving power than ethanol, so you'll only be diluting the solution.

Is that from personal experience? What's the highest mg/ml you can get with DMSO?

 

[Deleted member 59947]

Is that from personal experience?

No:

https://purehost.bath.ac.uk/ws/portalfiles/portal/187942283/Dermatopharmacokinetics_as_a_tool_to_characterise_the_performance_of_testosterone_transdermal_formulations

 

[Deleted member 59947]

What's the highest mg/ml you can get with DMSO?

With test base it starts to crash above 100mg/ml

With DHT it starts to crash above 50mg/ml

 

[BigOldBastard]

Quick update: Success! I just got 400ml/mg test base to hold in 100% DMSO. Has not crashed and is crazy powerful. I plan on testing 500mg/ml to see if that hold as well.

 

[OneStrongMutha]

Quick update: Success! I just got 400ml/mg test base to hold in 100% DMSO. Has not crashed and is crazy powerful. I plan on testing 500mg/ml to see if that hold as well.

Wow, what are you going to do with it at that strength?

 

[BigOldBastard]

Wow, what are you going to do with it at that strength?

Making Meso Great Again

 

[BigOldBastard]

Making Meso Great Again

Apply it in the morning, check levels mid-day. Give you an update when I get blood work done

 

[OneStrongMutha]

Apply it in the morning, check levels mid-day. Give you an update when I get blood work done

How many mgs a day are you going to run?

 

[BigOldBastard]

How many mgs a day are you going to run?

800

 

[hijoshiki]

800mg/day.

You'll need to keep us informed how that goes and you'd better put in another order for raws if your burning through it that fast.

 

[OneStrongMutha]

800mg/day.

You'll need to keep us informed how that goes and you'd better put in another order for raws if your burning through it that fast.

I feel like he might have misread my question. At least I hope so.

 

[BigOldBastard]

I feel like he might have misread my question. At least I hope so.

2 ml per day

 

[Deleted member 59947]

Quick update: Success! I just got 400ml/mg test base to hold in 100% DMSO. Has not crashed and is crazy powerful. I plan on testing 500mg/ml to see if that hold as well.

That's amazing! With no benzyl alcohol?
At 100mg/ml the solution is clear and doesn't crash but it leaves testosterone white residue on the skin.
Do you have residue after application?

 

[BigOldBastard]

That's amazing! With no benzyl alcohol?
At 100mg/ml the solution is clear and doesn't crash but it leaves testosterone white residue on the skin.
Do you have residue after application?

A little white residue, but not much

 

[Deleted member 59947]

A little white residue, but not much

That's unreal.
I'll try doubling my concentration to 200mg/ml and see if it crashes again.
Maybe my first test base batch when I tried those high concentrations was either not micronized or not pure.

If I can get away with not adding benzyl alcohol to the DMSO and not get headaches and blurry vision, I'd rather.

 

[Deleted member 59947]

Quick update: Success! I just got 400ml/mg test base to hold in 100% DMSO. Has not crashed and is crazy powerful. I plan on testing 500mg/ml to see if that hold as well.

Are you sure about your math?
I just intented 200mg/ml and the last bits barely dissolve even after a few hours.

Can you break down how many grams of test you put in how many ml of DMSO?

 

[BigOldBastard]

Are you sure about your math?
I just intented 200mg/ml and the last bits barely dissolve even after a few hours.

Can you break down how many grams of test you put in how many ml of DMSO?

4 grams in 10 ml of DMSO. Let it sit overnight.

 

[Deleted member 59947]

4 grams in 10 ml of DMSO. Let it sit overnight.

Impressive.
Eagerly waiting for bloodwork.
Ideally you want to draw at trough for it to be representative, ie right before next application.
There is a trend to draw bloods 5 hours after application in test cream users, which makes no sense at all.

You apply once or twice a day?

 

[BigOldBastard]

Impressive.
Eagerly waiting for bloodwork.
Ideally you want to draw at trough for it to be representative, ie right before next application.
There is a trend to draw bloods 5 hours after application in test cream users, which makes no sense at all.

You apply once or twice a day?

Twice a day