"To be completely safe, dimers, polymers, aggregates, improper folding, glycosylation, broken cross-linkages, pyrogens, and contaminants must be strictly controlled during manufacture and packaging. This molecule is fragile and the freeze drying and packaging process can further alter its structure. Such abnormalities may not block hormone activity, and the product may seem to work quite well in many cases, but the altered molecules may stimulate immune reactions and cause allergy and desensitization to HGH, with subsequent and permanent decrease in hormone response. Such autoimmunity has been reported with as little as one percent of the injected HGH in an altered form, causing the body to neutralize internally produced as well as injected HGH. Adverse reactions may also include anaphylactic shock."
