Date_Mike
Subscriber
im aware of the negative effects on cholesterol. Can you ELI5.So, bit of a difference between your "hepatotoxic" and my "stresses the liver". Typical liver stress indicators will be AST aka SGOT, ALT aka SGPT, HDL, and LDL. Oxandrolone is known to make these all worse.
Overall, you'll want your liver functioning at its best to help keep your HDL high, and LDL low ... and while generally we like to keep our AST and ALT low as well, it's worth noting that elevated levels don't always mean there's anything wrong with the liver -- it's possible to have elevated AST and ALT but actual liver functioning to be normal.
More if you want to find and click through a few yourself : Google Scholar -- (can use Sci-Hub: emancipation and democratisation of knowledge to access most paywalled papers)
A few additional selected resources:
("oxandrolone markedly increases hepatic lipase activity" ... seems consistent with "stresses the liver")
"Cholestatic jaundice with, rarely, hepatic necrosis and death; hepatocellular neoplasms and peliosis hepatis with long-term therapy; reversible changes in liver function tests also occur including increased bromsulfophthalein (BSP) retention, changes in alkaline phosphatase and increases in serum bilirubin, aspartate aminotransferase (AST, SGOT) and alanine aminotransferase (ALT, SGPT)."
Oxandrolone Side Effects: Common, Severe, Long Term
Learn about the side effects of oxandrolone, from common to rare, for consumers and healthcare professionals.www.drugs.com
https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/013718s023lbl.pdf (big ass giant warning in all caps on first page about liver cysts, liver failure, and liver cancer)
As for:
I don't know much about internal medicine. But I have noticed that Doxycycline (the current recommended treatment for chlamydia) is also not processed by the liver (it is primarily excreted by the gut and kidneys) but is also known to cause liver stress and in some cases, hepatotoxicity. Its half-life is also significantly increased in people who have a low-functioning or damaged liver. So, this logic about where something is processed vs. what it affects is definitely not always a clear-cut relationship.
Basic question - 6 week cycle at 60mg a day. Bloods prior are healthy on almost all accounts. Only abnormality was elevated CRP. Would I be fucked permanently from this cycle?
