Ah yes pussysomnia. What a terrible condition
MESO-Rx
Anabolic Steroids
Trenbolone & Testosterone
- Thread starter Michael Scally MD
- Start date
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- testosterone trenbolone
Worst fucking side EVER!!Ah yes pussysomnia. What a terrible condition
TESTOSTERONE
In-order to understand exactly how Testosterone Enanthate (commonly referred to as "test-e") builds muscle and burns fat, first well take a look at androgens and what they do in the body. You see, hormones are substances secreted by one cell that has an effect on the functions of another cell. Testosterone is manufactured in the Leydigs cells of the testes (in men) and the adult male produces between 2.5 and 11mgs of Test per day.
Testosterone induces changes in shape, size and also can change the appearance and the number of muscle fibers(7). Androgens like testosterone, which is exactly what Testosterone Enanthate is can protect your hard earned muscle from the catabolic (muscle wasting) glucocorticoid hormones(8), thus inhibiting their ability to send a message to muscle cells to release stored protein. Remember, testosterone sends a message to muscle cells to store more contractile protein (called actin and myosin); glucocorticoid hormones send the opposite message. In addition, Testosterone Enanthate has the ability to increase erythropoiesis (red blood cell production) in your kidneys(9), and a higher Red Blood Cell (RBC) count will improve endurance via better oxygenated blood. More RBCs can also improve recovery from strenuous physical activity. Of course, aggression levels can rise dramatically with the use of exogenous testosterone (15); however, its important to remember aggression in of itself is not a bad thing; what we do with it is what makes it right or wrong. At any rate, Testosterone Enanthate holds no mind altering traits or nature whatsoever.
All of these great benefits are to be had with the use of Testosterone Enanthate alone, but realistically, it will in most cases be part of a cycle containing one or more other steroids. People who are bulking will probably choose Deca Durabolin or Trenbolone compounds, and of course the possibility of powerful oral steroids like Anadrol or Dianabol. Then we have those who are cutting, and they will probably steer towards Equipoise and once again Trenbolone, along side compounds such as Anavar, Masteron, Winstrol and perhaps Primobolan; all are solid options. Very often users will administer Testosterone Enanthate once or twice a week, but blood levels are still above baseline with this steroid at around day eight (16).Common wisdom holds that the testosterone portion of any such cycle should be equal to or greater than any other injectable steroids portion (on a mg basis); however, this isnt always needed, but its a good rule of thumb to ensure no low testosterone condition exists.
As you may have suspected, Testosterone Enanthates anabolic/androgenic effects are dose dependent; the higher the dose the higher the muscle building effect(10). Lets take a look at exactly what kind of results we can expect from administration of Testosterone Enanthate:
Effects of 20 weeks of GnRH agonist plus Testosterone Enanthate administration on relative changes (mean SEM) in total LBM (A), appendicular LBM (B), and trunk LBM (C) (percent change from baseline) measured by DEXA. P values are results for ANOVA: *, P < 0.05 vs. all other dose groups for the multiple comparison tests using Student-Newman-Keuls; a, P < 0.05 vs. zero change.(11)
This chart shows that the subjects in this test made a roughly 15% gain in Lean Body Mass from 20 weeks of 600mgs/week of Testosterone Enanthate. That's pretty impressive, but the following set of charts is even more telling:
Change in fat-free mass (A), fat mass (B), leg press strength (C), thigh muscle volume (D), quadriceps muscle volume (E), sexual function (F), insulin-like growth factor I (G), and prostate-specific antigen (H). Data are means SE. *Significant differences from all other groups (P < 0.05); significant difference from 25-, 50-, and 125-mg doses (P < 0.05); +significant difference from 25- and 50-mg doses (P < 0.05); and significant difference from 25-mg dose (P < 0.05). (14)
Now this is very interesting. You'll note that the most fat was lost by the group in this study who used the highest dose of Testosterone Enanthate (600mgs/week), and the most Fat Free mass, Strength and Muscle Volume was gained, when compared to any of the lower doses studied (14). Basically, the more Testosterone Enanthate you use (and this holds true for almost all steroids), the more gains you'll get! Of course, that the previous statement will ruffle some feathers in the "less is more" club, but that's simply too bad; more Testosterone Enanthate = more muscle, more strength, more size, and less fat.
Did the men in this study experience side effects at the 600mg dose? Well, HDL cholesterol was lowered (but not total cholesterol or triglyceride levels), and two guys got Acne. Not exactly cause for a Senate Investigation. (14)
Of course, the usual nasty side effects you can get from any form of injectable testosterone are possible with Testosterone Enanthate; gynecomastia, water retention and high blood pressure are all possible, but they are very overstated or controllable in many instances.
A large percentage of those side effects occur from the body's ability to turn Testosterone Enanthate, which is again simply a testosterone hormone into estrogen via a ********* pathway mediated by the aromatase enzyme. This process, known as aromatization causes a portion of testosterone to be converted to estrogen. Aromatase Inhibitors, Anastrozole (Arimidex) and Letrozole (Femara) can combat this very effectively, and are usually necessary with doses over a gram per week, and often recommended with lower performance doses.
TRENBOLONE
The drug Trenbolone is, without a doubt, the most powerful injectable anabolic steroid used by athletes an weight lifters to gain muscle. However the full properties of the drug are not always fully understood. This profile will separate fact from fiction and help everyone decide if Trenbolone is right for them.
Trenbolone is similar to the highly popular steroid Nandrolone, in that they are both 19-nor steroids, meaning that a testosterone molecule has been altered at the 19th position to give us a new compound. Unlike Nandrolone however Trenbolone is an excellent mass and hardening drug with the majority of gains being muscle fiber, with minimal water retention (1) It has an unbelievable anabolic (muscle building) score of 500. When you compare that to Testosterone, which itself is a powerful mass builder, and has an anabolic score of 100 you can begin to fathom the muscle building potential of Trenbolone. What makes Trenbolone so anabolic? Numerous factors come into play. Trenbolone greatly increases the level of the extremely anabolic hormone IGF-1 within muscle tissue (2). And, its worth noting that not only does it increase the levels of IGF-1 in muscle over two fold, it also causes muscle satellite cells (cells that repair damaged muscle) to be more sensitive to IGF-1 and other growth factors(3). The amount of DNA per muscle cell may also be significantly increased (3).
Trenbolone also has a very strong binding affinity to the androgen receptor (A.R), binding much more strongly than testosterone (4). This is important, because the stronger a steroid binds to the androgen receptor the better that steroid works at activating A.R dependent mechanisms of muscle growth. There is also strong supporting evidence that compounds which bind very tightly to the androgen receptor also aid in fat loss. Think as the receptors as locks and androgen's as different keys, with some keys (androgen's) opening (binding) the locks (receptors) much better than others. This is not to say that AR-binding is the final word on a steroids effectiveness. Anadrol doesnt have any measurable binding to the AR& and we all know how potent Anadrol is for mass-building.
Trenbolone increases nitrogen retention in muscle tissue (5). This is of note because nitrogen retention is a strong indicator of how anabolic a substance is. However, it's incredible mass building effects do not end there. Trenbolone has the ability to bind with the receptors of the anti-anabolic (muscle destroying) glucocorticoid hormones (6). This may also has the effect of inhibiting the catabolic (muscle destroying) hormone cortisol (7).
Yet another amazing trait that must be noted is its ability to improve feed efficiency and mineral absorption in animals given the drug (8). To help you understand what this means for you, feed efficiency is a measurement of how much of an animals diet is converted into meat, and the more food it takes to produce this meat, the lower the efficiency. Conversely, the less food it takes to produce meat the, higher the efficiency& well you get the idea. Animals given Trenbolone gained high quality weight without having their diet adjusted, thus improving feed efficiency. Finding new compounds which can improve feed efficiency is a billion dollar industry, and has spawned many nutritional advances in the bodybuilding world over the last few decades (CLA, Whey Protein, and HMB are compounds which spring to mind as having first been introduced by the livestock industry). What does this translate to for the hard training athlete? The food you eat will be better utilized for building lean muscle, and vitamins and minerals are also better absorbed which may keep you healthier during cycle.
Trenbolone is also a highly androgenic hormone, when compared with Testosterone, which has an androgenic ratio of 100; Trenbolone's androgenic ratio is an astonishing 500. Highly androgenic steroids are appreciated for the effects they have on strength as well as changing the estrogen/androgen ratio, thus reducing water and under the skin. As if the report on Trenbolone was not good enough, it gets better; Trenbolone is extraordinarily good as a fat loss agent. One reason for this is its powerful effect on nutrient partitioning (9). It is a little known fact is that androgen receptors are found in fat cells as well as muscle cells(10), androgens act directly on the A.R in fat cells to affect fat burning.(11) the stronger the androgen binds to the A.R, the higher the lipolytic (fat burning) effect on adipose tissue (fat)(11). Since some steroids even increase the numbers of A.R in muscle and fat (11, 12) this fat loss effect would be amplified with the concurrent use of other compounds, such as Testosterone.
Trenbolone promotes red blood cell production and increases the rate of glycogen replenishment, significantly improving recovery (13). Like almost all steroids, it's effects are dose dependant with higher dosages having the greatest effects on body composition and strength. Mental changes are a notorious side effect of Trenbolone use (15), androgens increase chemicals in the brain that promote aggressive behavior(16), which can be beneficial for some athletes wanting to improve speed and power.
Trenbolone's chemical structure makes it resistant to the aromatize enzyme (conversion to estrogen) thus absolutely no percentage of Trenbolone will convert to estrogen. Trenbolone administration would not promote estrogenic side effects such as breast tissue growth in men (gynecomastia, bitch tits) accelerated fat gain, decline in fat break down and water retention. Trenbolone is also resistant to the 5- alpha-reductase enzyme, this enzyme reduces some steroid hormones into a more androgenic form, in this case however this does not matter. Trenbolone boasts an androgenic ratio of 500. It can easily cause adverse androgenic side effects in people who are prone to hair loss, prostate enlargement, oily skin and acne. Unfortunately Trenbolone's potential negative side effects do not end there. Trenbolone is also a noted progestin: it binds to the receptor of the female sex hormone progesterone (with about 60% of the actual strength progesterone) (17). In sensitive people this can lead to bloat and breast growth worse still, Trenbolone's active metabolite 17beta-trenbolone has a binding affinity to the progesterone receptor (PgR) that is actually greater than progesterone itself (18). No need to panic though, the anti-estrogens letrzole or fulvestrant can lower progesterone levels, and combat any progestenic sides. The use of a 19-nor compound like trenbolone also increases prolactin & . bromocriptine or cabergoline are often recommended to lower prolatin levels (20). Testicular atrophy (shrunken balls) may also occur; Human Chorionic Gonadotropin (HCG) used intermittently throughout a cycle can prevent this. (21) It is also wise for Tren users to closely monitor their cholesterol levels, as well as kidney function and liver enzymes, as Tren has the potential to negatively affect all of those functions. Finaplix, being a powerful progestin, will also shut down natural testosterone production which even a relatively small dose and keep the testosterone level suppressed for an extended period of time, this can lower libido and cause erectile dysfunction (fina dick). It is essential that you always stack Finaplix with testosterone.
The acetate ester is a very short-chain ester attached to the Finaplix molecule. It has an active life of 2-3 days but to keep blood levels of trenbolone elevated and steady, daily injections are often recommended. The acetate ester provides a rapid and high concentration of the hormone which is beneficial to those seeking quick gains, coupled with a rapid clearing time the acetate ester can be discontinued on the onset of adverse side effects.
Now that the properties of Trenbolone Acetate have been explained we can better understand how to use it in order to maximize its advantages. Evidence suggests that Finaplix when stacked with estrogen promotes more weight gain that Trenbolone alone(22), now Im not telling you to go pop some birth control with your Tren but the addition of aromatizing orals such as Dianabol and a long estered testosterone such as Cypionate or Enanthate would produce great gains in a bulking cycle. For a cutting cycle Finaplix is the best choice you have; Trenbolone's powerful effect on nutrient shuttling allows a user to restrict calories and remain in a state of positive nitrogen balance (remember what that means?). The cortisol reducing effect and binding to the glucocorticoid receptor will greatly reduce the catabolic effects of harsh dieting and excessive amounts of cardio and not to mention that Finaplix itself may burn fat (due to its strong AR-binding). A good choice to stack with Tren in a cutting cycle is Winstrol. Winstrol has a low binding affinity to the AR and thus will act in your body in vastly different ways than the Tren (i.e. in non-receptor mediated action). In addition, Winstrol is a DHT-based drug and Tren is a 19-nor& throw in some Testosterone (prop), and you'll have a cutting cycle which takes advantage of all 3 major families of Anabolic Steroids (Testosterone, 19-nor, and DHT), as well as vastly different AR-binding affinities and mechanisms of action.
Ironically, even though Trenbolone ( Tren ) is an excellent contest prep drug, it lowers your thyroid level(23), and this raises prolactin. I recommend taking T3 (25mcgs/day) along with your Tren to avoid elevating your prolactin too high via this route.
Also, this drug is a poor choice for athletes who rely on cardiovascular fitness to play a sport. Trenbolone ( Tren ), anecdotally at least, reduces many athletes ability to sustain high levels of endurance. Unfortunately, this makes Tren a poor choice for many.
As of now the main source of Trenbolone is from implants for cattle being converted into an injectable or transdermal compound, from powder, and of course Underground Labs. "Home brewing" powder or cattle implants seems to be the preferred method of obtaining injectable Trenbolone Acetate, because the user would have much more control over the potency and sterility of the drug. Trenbolone is much more expensive than other anabolic steroids ranging from 15 U.S dollars per gram of powder or 150 U.S for a single 10 ml bottle. The cost of Trenbolone should not matter, it is worth every penny.
In-order to understand exactly how Testosterone Enanthate (commonly referred to as "test-e") builds muscle and burns fat, first well take a look at androgens and what they do in the body. You see, hormones are substances secreted by one cell that has an effect on the functions of another cell. Testosterone is manufactured in the Leydigs cells of the testes (in men) and the adult male produces between 2.5 and 11mgs of Test per day.
Testosterone induces changes in shape, size and also can change the appearance and the number of muscle fibers(7). Androgens like testosterone, which is exactly what Testosterone Enanthate is can protect your hard earned muscle from the catabolic (muscle wasting) glucocorticoid hormones(8), thus inhibiting their ability to send a message to muscle cells to release stored protein. Remember, testosterone sends a message to muscle cells to store more contractile protein (called actin and myosin); glucocorticoid hormones send the opposite message. In addition, Testosterone Enanthate has the ability to increase erythropoiesis (red blood cell production) in your kidneys(9), and a higher Red Blood Cell (RBC) count will improve endurance via better oxygenated blood. More RBCs can also improve recovery from strenuous physical activity. Of course, aggression levels can rise dramatically with the use of exogenous testosterone (15); however, its important to remember aggression in of itself is not a bad thing; what we do with it is what makes it right or wrong. At any rate, Testosterone Enanthate holds no mind altering traits or nature whatsoever.
All of these great benefits are to be had with the use of Testosterone Enanthate alone, but realistically, it will in most cases be part of a cycle containing one or more other steroids. People who are bulking will probably choose Deca Durabolin or Trenbolone compounds, and of course the possibility of powerful oral steroids like Anadrol or Dianabol. Then we have those who are cutting, and they will probably steer towards Equipoise and once again Trenbolone, along side compounds such as Anavar, Masteron, Winstrol and perhaps Primobolan; all are solid options. Very often users will administer Testosterone Enanthate once or twice a week, but blood levels are still above baseline with this steroid at around day eight (16).Common wisdom holds that the testosterone portion of any such cycle should be equal to or greater than any other injectable steroids portion (on a mg basis); however, this isnt always needed, but its a good rule of thumb to ensure no low testosterone condition exists.
As you may have suspected, Testosterone Enanthates anabolic/androgenic effects are dose dependent; the higher the dose the higher the muscle building effect(10). Lets take a look at exactly what kind of results we can expect from administration of Testosterone Enanthate:
Effects of 20 weeks of GnRH agonist plus Testosterone Enanthate administration on relative changes (mean SEM) in total LBM (A), appendicular LBM (B), and trunk LBM (C) (percent change from baseline) measured by DEXA. P values are results for ANOVA: *, P < 0.05 vs. all other dose groups for the multiple comparison tests using Student-Newman-Keuls; a, P < 0.05 vs. zero change.(11)
This chart shows that the subjects in this test made a roughly 15% gain in Lean Body Mass from 20 weeks of 600mgs/week of Testosterone Enanthate. That's pretty impressive, but the following set of charts is even more telling:
Change in fat-free mass (A), fat mass (B), leg press strength (C), thigh muscle volume (D), quadriceps muscle volume (E), sexual function (F), insulin-like growth factor I (G), and prostate-specific antigen (H). Data are means SE. *Significant differences from all other groups (P < 0.05); significant difference from 25-, 50-, and 125-mg doses (P < 0.05); +significant difference from 25- and 50-mg doses (P < 0.05); and significant difference from 25-mg dose (P < 0.05). (14)
Now this is very interesting. You'll note that the most fat was lost by the group in this study who used the highest dose of Testosterone Enanthate (600mgs/week), and the most Fat Free mass, Strength and Muscle Volume was gained, when compared to any of the lower doses studied (14). Basically, the more Testosterone Enanthate you use (and this holds true for almost all steroids), the more gains you'll get! Of course, that the previous statement will ruffle some feathers in the "less is more" club, but that's simply too bad; more Testosterone Enanthate = more muscle, more strength, more size, and less fat.
Did the men in this study experience side effects at the 600mg dose? Well, HDL cholesterol was lowered (but not total cholesterol or triglyceride levels), and two guys got Acne. Not exactly cause for a Senate Investigation. (14)
Of course, the usual nasty side effects you can get from any form of injectable testosterone are possible with Testosterone Enanthate; gynecomastia, water retention and high blood pressure are all possible, but they are very overstated or controllable in many instances.
A large percentage of those side effects occur from the body's ability to turn Testosterone Enanthate, which is again simply a testosterone hormone into estrogen via a ********* pathway mediated by the aromatase enzyme. This process, known as aromatization causes a portion of testosterone to be converted to estrogen. Aromatase Inhibitors, Anastrozole (Arimidex) and Letrozole (Femara) can combat this very effectively, and are usually necessary with doses over a gram per week, and often recommended with lower performance doses.
TRENBOLONE
The drug Trenbolone is, without a doubt, the most powerful injectable anabolic steroid used by athletes an weight lifters to gain muscle. However the full properties of the drug are not always fully understood. This profile will separate fact from fiction and help everyone decide if Trenbolone is right for them.
Trenbolone is similar to the highly popular steroid Nandrolone, in that they are both 19-nor steroids, meaning that a testosterone molecule has been altered at the 19th position to give us a new compound. Unlike Nandrolone however Trenbolone is an excellent mass and hardening drug with the majority of gains being muscle fiber, with minimal water retention (1) It has an unbelievable anabolic (muscle building) score of 500. When you compare that to Testosterone, which itself is a powerful mass builder, and has an anabolic score of 100 you can begin to fathom the muscle building potential of Trenbolone. What makes Trenbolone so anabolic? Numerous factors come into play. Trenbolone greatly increases the level of the extremely anabolic hormone IGF-1 within muscle tissue (2). And, its worth noting that not only does it increase the levels of IGF-1 in muscle over two fold, it also causes muscle satellite cells (cells that repair damaged muscle) to be more sensitive to IGF-1 and other growth factors(3). The amount of DNA per muscle cell may also be significantly increased (3).
Trenbolone also has a very strong binding affinity to the androgen receptor (A.R), binding much more strongly than testosterone (4). This is important, because the stronger a steroid binds to the androgen receptor the better that steroid works at activating A.R dependent mechanisms of muscle growth. There is also strong supporting evidence that compounds which bind very tightly to the androgen receptor also aid in fat loss. Think as the receptors as locks and androgen's as different keys, with some keys (androgen's) opening (binding) the locks (receptors) much better than others. This is not to say that AR-binding is the final word on a steroids effectiveness. Anadrol doesnt have any measurable binding to the AR& and we all know how potent Anadrol is for mass-building.
Trenbolone increases nitrogen retention in muscle tissue (5). This is of note because nitrogen retention is a strong indicator of how anabolic a substance is. However, it's incredible mass building effects do not end there. Trenbolone has the ability to bind with the receptors of the anti-anabolic (muscle destroying) glucocorticoid hormones (6). This may also has the effect of inhibiting the catabolic (muscle destroying) hormone cortisol (7).
Yet another amazing trait that must be noted is its ability to improve feed efficiency and mineral absorption in animals given the drug (8). To help you understand what this means for you, feed efficiency is a measurement of how much of an animals diet is converted into meat, and the more food it takes to produce this meat, the lower the efficiency. Conversely, the less food it takes to produce meat the, higher the efficiency& well you get the idea. Animals given Trenbolone gained high quality weight without having their diet adjusted, thus improving feed efficiency. Finding new compounds which can improve feed efficiency is a billion dollar industry, and has spawned many nutritional advances in the bodybuilding world over the last few decades (CLA, Whey Protein, and HMB are compounds which spring to mind as having first been introduced by the livestock industry). What does this translate to for the hard training athlete? The food you eat will be better utilized for building lean muscle, and vitamins and minerals are also better absorbed which may keep you healthier during cycle.
Trenbolone is also a highly androgenic hormone, when compared with Testosterone, which has an androgenic ratio of 100; Trenbolone's androgenic ratio is an astonishing 500. Highly androgenic steroids are appreciated for the effects they have on strength as well as changing the estrogen/androgen ratio, thus reducing water and under the skin. As if the report on Trenbolone was not good enough, it gets better; Trenbolone is extraordinarily good as a fat loss agent. One reason for this is its powerful effect on nutrient partitioning (9). It is a little known fact is that androgen receptors are found in fat cells as well as muscle cells(10), androgens act directly on the A.R in fat cells to affect fat burning.(11) the stronger the androgen binds to the A.R, the higher the lipolytic (fat burning) effect on adipose tissue (fat)(11). Since some steroids even increase the numbers of A.R in muscle and fat (11, 12) this fat loss effect would be amplified with the concurrent use of other compounds, such as Testosterone.
Trenbolone promotes red blood cell production and increases the rate of glycogen replenishment, significantly improving recovery (13). Like almost all steroids, it's effects are dose dependant with higher dosages having the greatest effects on body composition and strength. Mental changes are a notorious side effect of Trenbolone use (15), androgens increase chemicals in the brain that promote aggressive behavior(16), which can be beneficial for some athletes wanting to improve speed and power.
Trenbolone's chemical structure makes it resistant to the aromatize enzyme (conversion to estrogen) thus absolutely no percentage of Trenbolone will convert to estrogen. Trenbolone administration would not promote estrogenic side effects such as breast tissue growth in men (gynecomastia, bitch tits) accelerated fat gain, decline in fat break down and water retention. Trenbolone is also resistant to the 5- alpha-reductase enzyme, this enzyme reduces some steroid hormones into a more androgenic form, in this case however this does not matter. Trenbolone boasts an androgenic ratio of 500. It can easily cause adverse androgenic side effects in people who are prone to hair loss, prostate enlargement, oily skin and acne. Unfortunately Trenbolone's potential negative side effects do not end there. Trenbolone is also a noted progestin: it binds to the receptor of the female sex hormone progesterone (with about 60% of the actual strength progesterone) (17). In sensitive people this can lead to bloat and breast growth worse still, Trenbolone's active metabolite 17beta-trenbolone has a binding affinity to the progesterone receptor (PgR) that is actually greater than progesterone itself (18). No need to panic though, the anti-estrogens letrzole or fulvestrant can lower progesterone levels, and combat any progestenic sides. The use of a 19-nor compound like trenbolone also increases prolactin & . bromocriptine or cabergoline are often recommended to lower prolatin levels (20). Testicular atrophy (shrunken balls) may also occur; Human Chorionic Gonadotropin (HCG) used intermittently throughout a cycle can prevent this. (21) It is also wise for Tren users to closely monitor their cholesterol levels, as well as kidney function and liver enzymes, as Tren has the potential to negatively affect all of those functions. Finaplix, being a powerful progestin, will also shut down natural testosterone production which even a relatively small dose and keep the testosterone level suppressed for an extended period of time, this can lower libido and cause erectile dysfunction (fina dick). It is essential that you always stack Finaplix with testosterone.
The acetate ester is a very short-chain ester attached to the Finaplix molecule. It has an active life of 2-3 days but to keep blood levels of trenbolone elevated and steady, daily injections are often recommended. The acetate ester provides a rapid and high concentration of the hormone which is beneficial to those seeking quick gains, coupled with a rapid clearing time the acetate ester can be discontinued on the onset of adverse side effects.
Now that the properties of Trenbolone Acetate have been explained we can better understand how to use it in order to maximize its advantages. Evidence suggests that Finaplix when stacked with estrogen promotes more weight gain that Trenbolone alone(22), now Im not telling you to go pop some birth control with your Tren but the addition of aromatizing orals such as Dianabol and a long estered testosterone such as Cypionate or Enanthate would produce great gains in a bulking cycle. For a cutting cycle Finaplix is the best choice you have; Trenbolone's powerful effect on nutrient shuttling allows a user to restrict calories and remain in a state of positive nitrogen balance (remember what that means?). The cortisol reducing effect and binding to the glucocorticoid receptor will greatly reduce the catabolic effects of harsh dieting and excessive amounts of cardio and not to mention that Finaplix itself may burn fat (due to its strong AR-binding). A good choice to stack with Tren in a cutting cycle is Winstrol. Winstrol has a low binding affinity to the AR and thus will act in your body in vastly different ways than the Tren (i.e. in non-receptor mediated action). In addition, Winstrol is a DHT-based drug and Tren is a 19-nor& throw in some Testosterone (prop), and you'll have a cutting cycle which takes advantage of all 3 major families of Anabolic Steroids (Testosterone, 19-nor, and DHT), as well as vastly different AR-binding affinities and mechanisms of action.
Ironically, even though Trenbolone ( Tren ) is an excellent contest prep drug, it lowers your thyroid level(23), and this raises prolactin. I recommend taking T3 (25mcgs/day) along with your Tren to avoid elevating your prolactin too high via this route.
Also, this drug is a poor choice for athletes who rely on cardiovascular fitness to play a sport. Trenbolone ( Tren ), anecdotally at least, reduces many athletes ability to sustain high levels of endurance. Unfortunately, this makes Tren a poor choice for many.
As of now the main source of Trenbolone is from implants for cattle being converted into an injectable or transdermal compound, from powder, and of course Underground Labs. "Home brewing" powder or cattle implants seems to be the preferred method of obtaining injectable Trenbolone Acetate, because the user would have much more control over the potency and sterility of the drug. Trenbolone is much more expensive than other anabolic steroids ranging from 15 U.S dollars per gram of powder or 150 U.S for a single 10 ml bottle. The cost of Trenbolone should not matter, it is worth every penny.
$150 for a 10ml?! This has to have been written by an UGL.... Lol
Haha I'm sure you are more than likely right
. It deff wasn't an\or was not written by me Google is my second best friend
but you WP, along with alot of other bros here will always be my numerouno
I know a dude at my gym who gets rid of his for $120. Fuck that Shit!!!
McCoy SC, Yarrow JF, Conover CF, Borsa PA, Tillman MD, Conrad BP, et al. 17b-Hydroxyestra-4, 9, 11-trien-3-one (Trenbolone) preserves bone mineralbdensity in skeletally mature orchiectomized rats without prostate enlargement. Bone 2012. http://www.thebonejournal.com/article/S8756-3282(12)00965-9/abstract
Forty, 10 month old male F344/Brown Norway rats were randomized into
Levator Ani Bulbocavernosus Muscle:
The androgen‐sensitive LABC muscle masses were
Administration of TE and TREN resulted in a 44% increase in the LABC compared to SHAM (pb0.01).
Moreover, ORX+TE and ORX+TREN animals experienced a 126% increase in LABC mass compared to ORX animals (pb0.01).
There was no significant difference between ORX+TE and ORX+TREN groups for LABC mass (p>0.05).
Forty, 10 month old male F344/Brown Norway rats were randomized into
- SHAM,
- ORX,
- ORX+TE (7.0 mg/week), and
- ORX+TREN (1.0 mg/week) groups.
Levator Ani Bulbocavernosus Muscle:
The androgen‐sensitive LABC muscle masses were
- 1.07±0.04 g SHAM,
- 0.68±0.03 g ORX,
- 1.54±0.03 g ORX+TE, and
- 1.54±0.04 g ORX+TREN.
Administration of TE and TREN resulted in a 44% increase in the LABC compared to SHAM (pb0.01).
Moreover, ORX+TE and ORX+TREN animals experienced a 126% increase in LABC mass compared to ORX animals (pb0.01).
There was no significant difference between ORX+TE and ORX+TREN groups for LABC mass (p>0.05).
Donner DG, Elliott GE, Beck BR, et al. Trenbolone improves cardiometabolic risk factors and myocardial tolerance to ischemia-reperfusion in male rats with testosterone-deficient metabolic syndrome. Endocrinology. http://press.endocrine.org/doi/abs/10.1210/en.2015-1603
The increasing prevalence of obesity adds another dimension to the pathophysiology of testosterone deficiency (TD) and potentially impairs the therapeutic efficacy of classical testosterone replacement therapy (TRT).
We investigated the therapeutic effects of selective androgen receptor modulation with trenbolone in a model of TD with the metabolic syndrome (MetS).
Male Wistar rats (n=50) were fed either a control standard rat chow (CTRL) or a high-fat/high-sucrose diet (HF/HS). Following 8 weeks of feeding, rats underwent sham surgery or an orchiectomy (ORX). Alzet mini-osmotic pumps containing either vehicle, 2 mg/kg/day testosterone (TEST) or 2 mg/kg/day trenbolone (TREN) were implanted in HF/HS+ORX rats.
Body composition, fat distribution, lipid profile and insulin sensitivity were assessed. Infarct size was quantified to assess myocardial damage following in vivo ischaemia-reperfusion, before cardiac and prostate histology was performed.
The HF/HS+ORX animals had increased subcutaneous and visceral adiposity; circulating triglycerides, cholesterol and insulin; and myocardial damage, with low circulating testosterone compared to CTRLs.
Both TEST and TREN protected HF/HS+ORX animals against subcutaneous fat accumulation, hypercholesterolaemia and myocardial damage. However, only TREN protected against visceral fat accumulation, hypertriglyceridaemia and hyperinsulinaemia; and reduced myocardial damage relative to CTRLs. TEST caused widespread cardiac fibrosis and prostate hyperplasia, which were less pronounced with TREN.
We propose that TRT may have contraindications for males with TD and obesity-related MetS. TREN treatment may be more effective in restoring androgen status and reducing cardiovascular risk in males with TD and MetS.
The increasing prevalence of obesity adds another dimension to the pathophysiology of testosterone deficiency (TD) and potentially impairs the therapeutic efficacy of classical testosterone replacement therapy (TRT).
We investigated the therapeutic effects of selective androgen receptor modulation with trenbolone in a model of TD with the metabolic syndrome (MetS).
Male Wistar rats (n=50) were fed either a control standard rat chow (CTRL) or a high-fat/high-sucrose diet (HF/HS). Following 8 weeks of feeding, rats underwent sham surgery or an orchiectomy (ORX). Alzet mini-osmotic pumps containing either vehicle, 2 mg/kg/day testosterone (TEST) or 2 mg/kg/day trenbolone (TREN) were implanted in HF/HS+ORX rats.
Body composition, fat distribution, lipid profile and insulin sensitivity were assessed. Infarct size was quantified to assess myocardial damage following in vivo ischaemia-reperfusion, before cardiac and prostate histology was performed.
The HF/HS+ORX animals had increased subcutaneous and visceral adiposity; circulating triglycerides, cholesterol and insulin; and myocardial damage, with low circulating testosterone compared to CTRLs.
Both TEST and TREN protected HF/HS+ORX animals against subcutaneous fat accumulation, hypercholesterolaemia and myocardial damage. However, only TREN protected against visceral fat accumulation, hypertriglyceridaemia and hyperinsulinaemia; and reduced myocardial damage relative to CTRLs. TEST caused widespread cardiac fibrosis and prostate hyperplasia, which were less pronounced with TREN.
We propose that TRT may have contraindications for males with TD and obesity-related MetS. TREN treatment may be more effective in restoring androgen status and reducing cardiovascular risk in males with TD and MetS.
Mayne
Well-known Member
Good read doc but let's see how many "Opinions on trt with tren" posts are we gonna see in the future
engman
New Member
"yea" to what the doc just said
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