Oral Suspensions WITHOUT Alcohol/Ethanol - What Can I Use?

[WeaponPharma]

Hi everyone

Firstly - please forgive my name “WeaponPharma” which probably implies I know something about brewing. I unfortunately don’t and chose my name for shits n giggles

I’ve got a bunch of raw powders which I would like to turn into usable oral suspensions.

Winstrol
Oxandrolone
Viagra
Cialis
Turinabol
Superdrol
Anadrol
Aromasin
DNP

I have PEG300

I also have ethanol

Many of the oral suspension recipes I have seen rely on ethanol/alcohol and often in significant amounts. Anavar for example, if I make 10 mg/ml I need to consume 4 or 5 ml of pure alcohol.

Surely there is another way?

I would be INCREDIBLY GRATEFUL if someone could provide me with advice on how to create oral suspension without ethanol which result in a proper suspension. That is, NOT a solution which calls on the user to shake a bottle (which is pretty unsatisfactory I think)

Thanks very much in advance everyone!

 

[Deskoze38192]

I would be INCREDIBLY GRATEFUL if someone could provide me with advice on how to create oral suspension without ethanol which result in a proper suspension. That is, NOT a solution which calls on the user to shake a bottle (which is pretty unsatisfactory I think)

Its the other way around
Oral suspension is when you have to shake the bottle for even distribution and the raw is suspended in the liquid vehicle.
You are actually looking for solution recipes, When the raw and the liquid are brought into a humongous mixture

 

[WeaponPharma]

Its the other way around
Oral suspension is when you have to shake the bottle for even distribution and the raw is suspended in the liquid vehicle.
You are actually looking for solution recipes, When the raw and the liquid are brought into a humongous mixture

this is gold - thank you brother. I should have known this, since i understand i am looking for liquids in which the raw powders are "soluble"

thank you again mate

anyone with a link or anything would be most appreciated

I have had a decent look around - I swear. This is not someone wanting to be spoon fed. By way of example, there is a great amount of pharmacological info on caymanchem.com about the pharmacokinetics of raw powders. Even so, I cannot find a satisfactory answer to creating a solution that does not involve ethanol. Please assist bros!

PS has anyone here tried a DNP solution? I know there is the issue with everything being dyed yellow, but i like the greater certainty the user can achieve in terms of dosage. the compound freaks me out for obvious reasons and I think capping present too much risk

 

[Deskoze38192]

Glad to help. Right now with certain raws I only do oral suspensions because they are easy so I can’t help with the solutions but I’m in to see what others might have to add with oral solutions as well. I am several years sober and consuming alcohol to take an oral is not something I want to do either.

 

[WeaponPharma]

Glad to help. Right now with certain raws I only do oral suspensions because they are easy so I can’t help with the solutions but I’m in to see what others might have to add with oral solutions as well. I am several years sober and consuming alcohol to take an oral is not something I want to do either.

then you are in precisely the same boat as me brother - I sacked alcohol more than a decade ago and dont want to go near the stuff!

for those with knowledge - please help a couple of recovering booze hounds avoid the bottle - give us your advice!!

 

[AlexDavis43]

Hi everyone

Firstly - please forgive my name “WeaponPharma” which probably implies I know something about brewing. I unfortunately don’t and chose my name for shits n giggles

I’ve got a bunch of raw powders which I would like to turn into usable oral suspensions.

Winstrol
Oxandrolone
Viagra
Cialis
Turinabol
Superdrol
Anadrol
Aromasin
DNP

I have PEG300

I also have ethanol

Many of the oral suspension recipes I have seen rely on ethanol/alcohol and often in significant amounts. Anavar for example, if I make 10 mg/ml I need to consume 4 or 5 ml of pure alcohol.

Surely there is another way?

I would be INCREDIBLY GRATEFUL if someone could provide me with advice on how to create oral suspension without ethanol which result in a proper suspension. That is, NOT a solution which calls on the user to shake a bottle (which is pretty unsatisfactory I think)

Thanks very much in advance everyone!

Its the other way around
Oral suspension is when you have to shake the bottle for even distribution and the raw is suspended in the liquid vehicle.
You are actually looking for solution recipes, When the raw and the liquid are brought into a humongous mixture

Whatever you choose, get one of these to make the most homogeneous possible. Can get used on eBay for like $50.

Way more efficient than getting a forearm workout by shaking the shit out of your liquid raws or doing whatever @Stanfordpharma1 does.

 

[AlexDavis43]

then you are in precisely the same boat as me brother - I sacked alcohol more than a decade ago and dont want to go near the stuff!

for those with knowledge - please help a couple of recovering booze hounds avoid the bottle - give us your advice!!

I stopped adding gin to my tonic years ago, but never even considered this. Totally different context so not a trigger?

I never once thought about drinking the alcohol I use to sterilize stoppers, injection sites, et cetera

 

[GreenAmine]

It's a bit viscous, but propylene glycol can be used instead of ethanol. The solubility of essentially anything with the basic cholesterol molecular skeleton is incredibly soluble in PG.

You could even play around with how much water you can add to decrease the viscosity but still maintain solubility.

 

[patriotmuscle1]

I use Humco flavor plus oral suspension. I don't know why it's not more common. Maybe there's something I don't know about it. I simply measure the raw powder into 30ml of solution and stir and then put into 30ml dropper vial. I can make the concentration whatever I want.. 5mg-100mg per ml. I've never done anything less then 1mg per ml.
I then shake the bottle well before each dose.
Can add Humco sweet like 50/50 mix for a sweet flavor.
I've used this for 3 compounds for myself and seemed fine.
Maybe someone has more experience and can give more input on this method I use, if it's good or bad?
Humco 009116001 Flavor Plus Compounding Oral Suspension, 16oz Amazon.com

 

[patriotmuscle1]

I use Humco flavor plus oral suspension. I don't know why it's not more common. Maybe there's something I don't know about it. I simply measure the raw powder into 30ml of solution and stir and then put into 30ml dropper vial. I can make the concentration whatever I want.. 5mg-100mg per ml. I've never done anything less then 1mg per ml.
I then shake the bottle well before each dose.
Can add Humco sweet like 50/50 mix for a sweet flavor.
I've used this for 3 compounds for myself and seemed fine.
Maybe someone has more experience and can give more input on this method I use, if it's good or bad?
Humco 009116001 Flavor Plus Compounding Oral Suspension, 16oz Amazon.com

There is also ora plus its a different brand with same options of flavors and sugar free versions..
Both the ora plus and humco are used by pharmacies to make oral solutions for example to make oral Adderall at 1mg per ml/100ml .. 100mg of Adderall or 10-10mg tabs and 100ml of humco or ora plus. Crush in mortar and pestle the tabs or raws.. slowly add solution to make paste ..then continue to add remaining solution and blend. Then dispense into container.
I assumed if was good enough for pharmacies to get dosing accurate for children and adults it would work fine for me with AAS. Note I add %5 over dose with my aas solutions. Hope this helps. Has worked well for me so far

 

[Deskoze38192]

I use Humco flavor plus oral suspension. I don't know why it's not more common. Maybe there's something I don't know about it. I simply measure the raw powder into 30ml of solution and stir and then put into 30ml dropper vial. I can make the concentration whatever I want.. 5mg-100mg per ml. I've never done anything less then 1mg per ml.
I then shake the bottle well before each dose.
Can add Humco sweet like 50/50 mix for a sweet flavor.
I've used this for 3 compounds for myself and seemed fine.
Maybe someone has more experience and can give more input on this method I use, if it's good or bad?
Humco 009116001 Flavor Plus Compounding Oral Suspension, 16oz Amazon.com

Yes this is exactly what I do as well. Whet you are doing is just fine. I make all my oral suspensions in Humco. There is a raw that I use that Humco cannot be used, Telmisartan. It affects the PH too much and Telmisatan needs to be in a certain range. Other than that Humco for a vehicle in oral suspensions is excellent imho.
But the OP is asking about recipes to make oral solutions. And specifically oral
solutions without the use of alcohol as a solvent.

 

[Deskoze38192]

It's a bit viscous, but propylene glycol can be used instead of ethanol. The solubility of essentially anything with the basic cholesterol molecular skeleton is incredibly soluble in PG.

You could even play around with how much water you can add to decrease the viscosity but still maintain solubility.

Great information. Thanks. Will adding water to reduce viscosity greatly affect shelf life in your opinion? Thenks

 

[WeaponPharma]

Ok this is awesome - thanks so much you guys. This Humco product you guys talk about is not available here in Australia so far as I am aware, but I think I will try a few diff paracetamol/ibuprofen solutions to see if can achieve full solubility. It’s all trial and error I guess.

Ps adderall is the most glorious thing I have ever put in my body. Pretty sure I’d be a full blown street walking junkie if I lived in the US and had access to it on the reg

 

[patriotmuscle1]

Yes this is exactly what I do as well. Whet you are doing is just fine. I make all my oral suspensions in Humco. There is a raw that I use that Humco cannot be used, Telmisartan. It affects the PH too much and Telmisatan needs to be in a certain range. Other than that Humco for a vehicle in oral suspensions is excellent imho.
But the OP is asking about recipes to make oral solutions. And specifically oral
solutions without the use of alcohol as a solvent.

I seen that he wants solutions.. and seemed to be on the fence about suspension.. alot of people are because they think shaking it before use means the administration dosing will be off.. and I suppose it can be but from the research I've done it seems it's pretty accurate and easier to produce. My thought was this route is an alternative to solutions.
I did not know telmisartan is on the no go lost with humco..thanks for that info.. thats gonna be in my stack very soon should have been already honestly.
And I may be wrong and I'll try to find it again. I believe I found a paper where they described an additive to add to humco to alter ph for a couple medications. I will try to find it of its worth sharing.
I appreciate the feedback sir.

 

[Deskoze38192]

And I may be wrong and I'll try to find it again. I believe I found a paper where they described an additive to add to humco to alter ph for a couple medications. I will try to find it of its worth sharing.
I appreciate the feedback sir.

That’s is good to know. I’ll take a look and if you can find it I would appreciate it. Thank you

 

[GreenAmine]

Great information. Thanks. Will adding water to reduce viscosity greatly affect shelf life in your opinion? Thenks

It can at a certain point. Generally, less than 15% water content is unconducive to microbial growth.

 

[Deskoze38192]

It can at a certain point. Generally, less than 15% water content is unconducive to microbial growth.

Thank you for that info

 

[amindzeye]

Yes this is exactly what I do as well. Whet you are doing is just fine. I make all my oral suspensions in Humco. There is a raw that I use that Humco cannot be used, Telmisartan. It affects the PH too much and Telmisatan needs to be in a certain range. Other than that Humco for a vehicle in oral suspensions is excellent imho.
But the OP is asking about recipes to make oral solutions. And specifically oral
solutions without the use of alcohol as a solvent.

What were you using for telmisartan?

 

[Deskoze38192]

What were you using for telmisartan?

Didn’t feel like capping so I’m just weighing out 80mg at a time

 

[WeaponPharma]

To the OP (me!) - I discovered the answer and it was staring me in the face… everywhere I look on the internet I find recipes for creating solutions with raw powders by using PEG and then alcohol/ethanol. The raw powders are placed in the PEG, which has been preheated, and you stir it until it dissolves. Once it dissolves, you have a solution. This is the answer for many raw powders. Increase the amount of PEG to arrive at your desired mg/ml OR simply add water and save yourself some money. PEG is soluble in water. Note: the solution will lack the benefits that alcohol brings, which I seem to recall was sterility or something, but since it is only being swallowed and not injected, it shouldn’t matter much