17SS
Member
Atorvastatin makes me ache all over. Not sure about Rosuvastatin side effects but it has to be safer long term vs atorvastatin.
MESO-Rx
Anabolic Steroids
Update on statins
- Thread starter 120nmol
- Start date
egruberman
Well-known Member
Rosuvastatin tends to cause myalgia less often (2-3%) than atorvastatin (3-5%) in clinical trials. Myalgia is associated with higher doses, 20-40mg for Rosuvastatin, 40-80mg with atorvastatin. Not also can cause some insulin resistance at those doses.
Rosuvastatin is more efficacious at lower doses relative to atorvastatin. 10mg of Rosuvastatin will get 85% of the total efficacy of the max dose. 5mg per day or every other day will also lower lipids a great deal.
Those that do experience myalgia with one can generally tolerate the other as they are metabolized differently. Supplementing with CoQ10 may prevent myalgia from occurring in folks that high intensity exercise.
I wouldn’t avoid statins entirely if I wanted to manage lipids. They work really well. I’d try different combos and doses before giving go up on them.
Any idea how to convince my doctor to prescribe me both rous and ezetimibe while having quite a very very good lipids panel results?
I'm not in the USA so to get the meds for free I need my doctor to write me a prescription, thing is... I need to give him/her a good reason lol
Vanargandar
Well-known Member
Family history of high cholesterol, uncle/dad currently taking that medication combo and it works really well for them. Just say you want to be proactive about your health.
egruberman
Well-known Member
If you have a very good lipid panel, I wouldn't worry about taking a statin. What is "very good"?
It's a little bit hard I guess to justify any of those meds with this kind of lipids panel isn't it? I'm not boosting I'm just trying to reduce as much as possible any possible harm coming from AAS use
MA11
Member
Wait, you have LDL 50 and you do not take any statins?
Yes and I'm on cycle
As you can clearly tell from the HDL
MA11
Member
Wow. If I'd have the lipid profile of a virgin mermaid, a statin would be the last thing on my mind.
Any CVD in your family or what is your concern?
I just hoped I could raise the HDL and I need to recheck the apoB because the one I posted was on less AAS then now so I'm not sure I still have an ApoB of 22.
Not that I know, I just hoped I could keep these level low and maybe optimize it even further?
Maybe only ezetimibe 10mg?
Or maybe I'll just keep checking the lipids and wait for it to get worse before starting to use any lipid meds.
MA11
Member
I might be prejudiced because 10 mg rosuvastatin gave me quad and knee pain. Also statins can cause insulin resistance (unlikely with low dose) and why would you risk that?
Yeah that makes sense, even so I wasn't planning on taking more than 5mg of rosuvastatin.
I'll probably put the idea on hold and keep checking my lipids and see If they get worse.
I take 10mg rosuvastatin daily, but my lipids are still borderline out-of-range. My doctor doesn't seem to want to do anything more, but I've got a supply of ezetimibe and fenofibrate ready to go if/when the numbers change due to cycle. I figure it's better to be prepared and not need it than need it and not have it, and the only way to really know you need it is regular testing.
I think 10mg Ezetimibe should be the first line of defense, followed by 5mg Rosuvastatin. My LDL was 25 most recently on this combo.
egruberman
Well-known Member
This.
Tom Dayspring suggests that those that are at high risk keep their ApoB under 60mg/dL and those that aren’t under 80mg/dL.
You’re fine.
10mg of Lipitor took my ApoB from 130 to 83. I wonder what tacking on 10mg of Zetia would do...
I would highly recommend adding that, to get it even lower.
egruberman
Well-known Member
Likely drop it another 10-15mg/dL. If you can add in bempedoic acid as well, you’ll likely be well under 60mg/dL.
MA11
Member
So I took 10 mg rosuvastatin for approx 3 months. That gave me knee and quad pain. No bloods unfortunately.
Then I got prescribed 10 mg Atorvastatin and that improved the pain but not how it should. Meanwhile I started coq10 supplementation.
LDL went from 150 to 90. Meh
Now I got nustendi which a a ezetimib/bempedoic acid mix. I will report how that helped but this probably won't be as effective as a statin anyway.
Here's the plan:
I'll take the nustendi and will reintroduce 5 mg of a statin while supplementing coq10.
I'll go from 3x30 min cardio a week to 180 min a week. My diet is fairly good already anyway.
I'll report back.
Then I got prescribed 10 mg Atorvastatin and that improved the pain but not how it should. Meanwhile I started coq10 supplementation.
LDL went from 150 to 90. Meh
Now I got nustendi which a a ezetimib/bempedoic acid mix. I will report how that helped but this probably won't be as effective as a statin anyway.
Here's the plan:
I'll take the nustendi and will reintroduce 5 mg of a statin while supplementing coq10.
I'll go from 3x30 min cardio a week to 180 min a week. My diet is fairly good already anyway.
I'll report back.
egruberman
Well-known Member
You could try to get Praluent or Repatha. Both are available in Europe. Also maybe try pravastatin. It has the least reported side effects of any statin. It’s not used frequently because it’s not as strong as either Rosuvastatin or Atorvastatin, making it less appropriate for most of the people getting treatment for ASCVD 8’ the US, ie folks that have had or are about to have an MI.
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