Jacob Ladder
New Member
What about newbie cycling dbol for a first cycle? Anybody recommend this?
MESO-Rx
Anabolic Steroids
Anabolic Steroids & Liver [GI]
- Thread starter Michael Scally MD
- Start date
MoriorInvictus
New Member
I used Dbol orals for about 6 weeks once! I was experiencing head aches and weird body aches. Went to the doctor and she ordered blood work done. My liver values were through the roof. I had to come clean and tell the Doc what was going on, after a good mother son talk (my doctor is like a mom to me) I quit the Dbol and haven't touched orals since. I was taking Milk Thistle before, during and Post cycle but it definitely didn't help during. I went back to the Doc 4 months later and my blood work showed normal liver function. Was some seriously scary shit!!
Jacob Ladder
New Member
What's yo recommendation for a newbie cycle then? Just running some test? From what I've read-using a needle seems like the safer route.
so kind and thoughtful of you
MoriorInvictus
New Member
I'm still a little naive to the AAS scene. I know a little but probably only enough to be dangerous. If I were you I would either start a new thread or look to see if there is an existing thread with recommendations from some of the senior members here, there are some very knowledgeable guys on here. But personally I like Sustanon and Test Prop.
Khurana A, Dasanu CA. Hepatitis associated aplastic anemia: case report and discussion. Conn Med 2014;78(8):493-5. http://connmed.csms.org/i/368197
Aplastic anemia (AA) is thought to represent an autoimmune disorder leading to generation of activated CD8+ T-cells that target the bone marrow precursors. Hepatitis associated aplastic anemia (HAAA) is a subtype of aplastic anemia that develops within several months ofan episode of acute hepatitis. Etiologic agents include hepatitis viruses (A-E and G), Epstein-Bar virus, cytomegalovirus, HIV, parvovirus B19, and echoviruses amongst others. However, most HAAA cases are labeled "idiopathic" as the inciting agent cannot be identified. Drugs and/or toxins are rarely causal factors. We describe herein a unique case of HAAA linked with the anabolic steroid methasterone that caused a transient cholestatic hepatitis and, subsequently, a severe aplastic anemia in a young man.
Aplastic anemia (AA) is thought to represent an autoimmune disorder leading to generation of activated CD8+ T-cells that target the bone marrow precursors. Hepatitis associated aplastic anemia (HAAA) is a subtype of aplastic anemia that develops within several months ofan episode of acute hepatitis. Etiologic agents include hepatitis viruses (A-E and G), Epstein-Bar virus, cytomegalovirus, HIV, parvovirus B19, and echoviruses amongst others. However, most HAAA cases are labeled "idiopathic" as the inciting agent cannot be identified. Drugs and/or toxins are rarely causal factors. We describe herein a unique case of HAAA linked with the anabolic steroid methasterone that caused a transient cholestatic hepatitis and, subsequently, a severe aplastic anemia in a young man.
Luciano RL, Castano E, Moeckel G, Perazella MA. Bile acid nephropathy in a bodybuilder abusing an anabolic androgenic steroid. Am J Kidney Dis 2014;64(3):473-6. http://www.ajkd.org/article/S0272-6386(14)00883-X/abstract
Bile acid nephropathy, also known as cholemic nephrosis or nephropathy, is an entity that can be seen in patients with severe cholestatic liver disease. It typically is associated with acute kidney injury (AKI) with various forms of hepatic disease. Most often, patients with severe obstructive jaundice develop this lesion, which is thought to occur due to direct bile acid injury to tubular cells, as well as obstructing bile acid casts. Patients with end-stage liver disease also can develop AKI, in which case a more heterogeneous lesion occurs that includes hepatorenal syndrome and acute tubular injury/necrosis. In this circumstance, acute tubular injury develops from a combination of hemodynamic changes with some contribution from direct bile acid-related tubular toxicity and obstructive bile casts. We present a case of AKI due to bile acid nephropathy in a bodybuilder who developed severe cholestatic liver disease in the setting of anabolic androgenic steroid use.
Bile acid nephropathy, also known as cholemic nephrosis or nephropathy, is an entity that can be seen in patients with severe cholestatic liver disease. It typically is associated with acute kidney injury (AKI) with various forms of hepatic disease. Most often, patients with severe obstructive jaundice develop this lesion, which is thought to occur due to direct bile acid injury to tubular cells, as well as obstructing bile acid casts. Patients with end-stage liver disease also can develop AKI, in which case a more heterogeneous lesion occurs that includes hepatorenal syndrome and acute tubular injury/necrosis. In this circumstance, acute tubular injury develops from a combination of hemodynamic changes with some contribution from direct bile acid-related tubular toxicity and obstructive bile casts. We present a case of AKI due to bile acid nephropathy in a bodybuilder who developed severe cholestatic liver disease in the setting of anabolic androgenic steroid use.
Interesting, the authors state HRS is, at least in part, the consequence of Bile Acid precipitation.
Yet when considering the potential for low flow hemodynamic states in those with ESLD it's really not to surprising the overabundance of bile is one reason these patients are a prime setup for not only additional hepatic injury buy also for the development of AKI.
Yet when considering the potential for low flow hemodynamic states in those with ESLD it's really not to surprising the overabundance of bile is one reason these patients are a prime setup for not only additional hepatic injury buy also for the development of AKI.
“His medication regimen included nandrolone injection, 400 mg, twice per week; testosterone injection, 400 mg, once per week; oral methandrostenolone, 60 mg, daily; occasional ibuprofen, 200 mg, approximately 1-2 times per month; supplements (details of which were not known); and protein shakes.”
Do they comment on his age, duration of Oral D-Bol use, or any other RF for the development of hepatic injury?
underarock24
New Member
Even running injectable should you take a lI've support? If so how long should you preload it before strating a cycle?
First - the use of AAS wo the addition of a 17Alkyl group are infinitely LESS HEPATOXIC
and the includes essentially ALL injectable AAS.
Second - the 17 Alkyl group is necessary for the oral ABSORPTION OF ANY AAS. For example, Proviron does NOT include a 17 Alkyl group AND as a result it's oral bioavailability approximates ONE PERCENT!
Third - First time cyclers should only be using Test with perhaps the addition of an AI. I have found for many an AI alone is more than adequate for first time runners.
Fourth - As in this study it's really difficult to KNOW for sure what "AAS" is actually present in those "anabolics" received from UGLs
Fifth - Because of number 4 it would not be at all unusual to note the presence of "designer agent" some of which are believed to be even MORE HEPATOTOXIC than their parent compounds.
Sixth - I honestly suspect what you were using was more likely to be a designer AAS bc unless you have some unknown predisposition to hepatic injury even ORAL agents cause much more than a doubling of at most a tripling of LFT's IMO.
FINALLY NOOBS should always err on the side of caution and use those PEDs which are the safest and most reliable based on existing evidence, IMO
Absolutely NOT!
They (liver support compounds) are worthless, save your money for PCT fella.
(That's exclusive of the fact hepatic injury from injectables is VERY hard to document IN ISOLATION)
Yea I've heard it all before but for completeness sake, which study are you referring to?
The one done on rats or another performed of patients with end stage liver disease there are several more but they are ALL COMPARING APPLES to ORANGES from an evidence based perspective.
The one done on rats or another performed of patients with end stage liver disease there are several more but they are ALL COMPARING APPLES to ORANGES from an evidence based perspective.
underarock24
New Member
Sorry about the grammar. My phone can be a pin in the ass lol.
BYE CONTAGION!!!
underarock24
New Member
Lol the movie? Lol
Any alcohol mixed with the dbol? I've only run one cycle before and it included dbol.... thinking of running dbol again, liver issues scare me although I don't drink.
Look the problem with any ORAL is KNOWING WTF they contain, bc many don't contain jack shit, let alone an anabolic agent!!
Don't believe me? HAVE THEM TESTED !!!
FYI - define SCARE!
Don't believe me? HAVE THEM TESTED !!!
FYI - define SCARE!
Scare as in don't want any part of liver problems or any organ problems in general!
Similar threads
