Yes,
Alot of literature coming out with guys switching to Eod or Ed on smaller frequent injections..... Definitely better estrogen control. I believe what my doctor told me, is if you have a higher SHBG, more frequent injections are better. We found e5d works best for me.
I would not be so concerned about estrogen, my doctor explained that even on TRT its okay to have a slightly higher estrogen, what he watches for is symptoms such as gynocamastia, but he explained again that is how your body is utilizing the hormone. A couple years back, I kept my estrogen in the low 30s, high 20s and I always felt flat and my joints were killing me. Now my estradiol is around 60+ and I feel awesome. Alot of doctors are switching their methods.
Plus, longterm AI's are very bad for your arteries, lipids, and joints.