@Type-IIx
I've done some experimenting with Primo and tend to like it. It has a low side effect profile, but it does have a tendency to drop my estrogen levels, so running it at a proper ratio to Test is key for me.
Too much primo relative to test tanks my estrogen, followed by my lipids, and causes many low estrogen side effects for me.
Ex:
I was running
70mg Test E
200iu HCG / day
75iu HMG 2 x week
My E2 levels were staying in mid 50s with my total testosterone around 650. I was doing a fertility protocol. Adding in 170mg of primo dropped my Total estrogen (Not E2, but total) to 16 pg/mL (ref range 31-167). This was a significant drop since my E2 was on the higher end before adding primo.
I adjusted my protocol:
Test to 87.5mg / week
Primo to 70mg / week.
Total E2 increased to 90 pg/mL
E2 ultrasensitive was 29
After further experimentation I'm currently running Test about 25-30% higher than my Primo and this has been working great at TRT+ dosages.
How people respond will vary and the best thing to do is start with a comfortable Testosterone dosage and slowly add in primo....allow 4-8 weeks for your body to stabilize and then do bloodwork and adjust from there. (Same with any compound)